Alpha-ketoglutarate-magnesium, izwi kandi ku izina rya AKG-Mg, ni uruganda rukomeye, kandi uku guhuza kudasanzwe kwa Alpha-Ketoglutarate na Magnesium byagaragaye ko bifite inyungu nyinshi zishobora guteza ubuzima bwiza muri rusange. Alpha-ketoglutarate nigice cyingenzi cyinzira ya Krebs, uburyo bwibanze bwumubiri bwo kubyara ingufu. Iyo uhujwe na magnesium, AKG-Mg ifasha kongera urwego rwingufu. Abantu benshi bafata Alpha-ketoglutarate-magnesiumas ibiryo byongera ibiryo bitandukanye byubuzima.
Magnesium Alpha-Ketoglutarate, izwi kandi ku izina rya AKG-Magnesium, ni ibintu bisanzwe bibaho bigira uruhare runini mu kubyara ingufu na metabolism mu mubiri.
α-Ketoglutarate ni urufunguzo rwagati muri tricarboxylic aside (TCA), inzira ya metabolike itanga ingufu binyuze mu okiside ya karubone, amavuta, na proteyine. Ku rundi ruhande, magnesium ni imyunyu ngugu ikomeye igira uruhare mu mikorere myinshi ya physiologiya mu mubiri, harimo no gukora sisitemu zitandukanye za enzyme, kandi ikagira uruhare muri poroteyine na metabolism. Iyo ibyo bice byombi bihujwe, bikora magnesium alpha-ketoglutarate, byagaragaye ko bifite akamaro kanini mubuzima.
Alpha-ketoglutarate-magnesium ishyigikira ubushobozi bwumubiri bwo kubyara ingufu. Nkumukinyi wingenzi muri cycle ya TCA, Alpha-ketoglutarate-magnesium ifasha guhindura intungamubiri ziva mubiryo muri adenosine triphosphate (ATP), ifaranga ryibanze ryingirabuzimafatizo. Ibi bifasha kongera ingufu muri rusange kandi birashobora kugirira akamaro cyane abantu bakora imyitozo ikomeye.
Usibye uruhare rwayo mu gutanga ingufu, Alpha-ketoglutarate-magnesium ifite kandi antioxydants ifasha kurinda umubiri imbaraga za okiside ndetse n’ibyangizwa na radicals yubuntu.
Muri rusange, Alpha-ketoglutarate-magnesium ni ibintu bisanzwe bibaho byakozweho ubushakashatsi ku nyungu zishobora kugira ku buzima, harimo uruhare rwayo mu gutanga ingufu, ibikorwa bya antioxydeant, gukira imitsi, ndetse n’ubuzima bw’umutima.
Ketoglutarate, izwi kandi ku izina rya alpha-ketoglutarate, ni ikintu cy'ingenzi muri cycle citricike, inzira yo hagati yo guhinduranya ingufu mu ngirabuzimafatizo. Nibintu byingenzi muguhindura ibiryo imbaraga kandi bigakorwa ningirangingo z'umubiri. Usibye uruhare rwayo mukubyara ingufu, ketoglutarate yasanze ifite indi mirimo myinshi yingenzi mumubiri.
Bumwe mu buryo bukoreshwa bwa ketoglutarate ni uruhare rwayo muri metabolism aside amine. Ifite uruhare mubikorwa byo kwanduza, aribyo kwimura itsinda rya amino kuva aside amine kuri acide ya keto. Iyi nzira ningirakamaro muguhuza andi acide amine no kubyara ibintu bitandukanye byingenzi mumubiri. Ketoglutarate ni integuza ya synthesis ya glutamate, urufunguzo rwa neurotransmitter muri sisitemu yo hagati yo hagati. Ifite kandi uruhare muri synthesis ya proline na arginine, acide ebyiri zingenzi za amino zifite uruhare runini mumubiri.
Ketoglutarate nayo igira uruhare mukugenzura sisitemu yumubiri. Byagaragaye guhindura imikorere yingirabuzimafatizo kandi bifite ingaruka zo kurwanya inflammatory. Ubushakashatsi bwerekanye ko ketoglutarate ishobora kubuza umusaruro wa cytokine ikwirakwiza no guteza imbere umusaruro wa selile T igabanya ubukana.
Ubundi buryo bukoreshwa bwa ketoglutarate nubushobozi bwayo bwo gushyigikira imikorere ya siporo no gukira. Byagaragaye ko byongera ingufu mu gihe cyimyitozo ngororamubiri no kongera kwihangana. Byongeye kandi, byagaragaye ko bigabanya kwangirika kwimitsi no guteza imbere gukira vuba nyuma yimyitozo ikaze.
Usibye ingaruka zacyo zo guhindura no kongera imikorere, ketoglutarate yanakozweho ubushakashatsi ku ruhare rushoboka mu kuvura indwara zimwe na zimwe. Ubushakashatsi bwerekana ko bushobora kugira ingaruka nziza mubihe nka syndrome de fatigue idakira na fibromyalgia, aho umusaruro w'ingufu n'imikorere ya mito-iyonona. Kuzuza ketoglutarate birashobora gushyigikira imikorere ya mito-iyambere kandi bigateza imbere ingufu muri ibi bihe.
Alpha-ketoglutarate ni urugingo ngengabuzima rufite uruhare runini mu guhinduranya ingufu. Nibintu byingenzi hagati ya acide citricike, inzira ingirabuzimafatizo zitanga ingufu binyuze muri okiside ya karubone, amavuta, na proteyine.
Ku rundi ruhande, Magnesium, ni imyunyu ngugu ya ngombwa igira uruhare mu myitwarire irenga 300 mu mubiri. Ifite uruhare mu kubyara ingufu, imikorere yimitsi, hamwe na ADN na synthesis. Magnesium izwi kandi ku bushobozi bwo gushyigikira ubuzima bw'umutima, kunoza umutima, no kugabanya imitsi n'imitsi.
Iyo alpha-ketoglutarate na magnesium bihujwe, ingaruka zazo zishobora kugira ingaruka zikomeye kubuzima muri rusange. Inyungu zingenzi zuruvange ni uko alpha-ketoglutarate na magnesium byombi bigira uruhare mungufu za metabolism no mumikorere yimitsi, bigatuma biba byiza mukuzamura kwihangana, imbaraga no gukira. Byongeye kandi, alpha-ketoglutarate byagaragaye ko byongera umusaruro wa nitric oxyde, utezimbere amaraso kandi bikongerera ogisijeni imitsi.
Byongeye kandi, guhuza alpha-ketoglutarate na magnesium bishobora gufasha gusaza neza. Mugihe tugenda dusaza, imibiri yacu ntigikora neza kubyara ingufu no gusana ingirangingo zangiritse. Alpha-ketoglutarate na magnesium birashobora gufasha kugabanya izo ngaruka mugushigikira imikorere ya mito-iyambere, ifite akamaro kanini mugukora ingufu no gusana selile. Na none, ibi birashobora kugabanya ibyago byindwara ziterwa nimyaka no kuzamura imibereho muri rusange.
Byongeye kandi, ingaruka ziterwa na alpha-ketoglutarate na magnesium zishobora kugera kubuzima bwo mumutwe. Ubushakashatsi bwerekana ko magnesium ifite ubushobozi bwo kugabanya imihangayiko, guhangayika, no kwiheba, mugihe alpha-ketoglutarate yerekanwe gushyigikira imikorere yubwenge. Iyo uhujwe, ibyo bice byombi bishobora kugira ingaruka zuzuzanya kumyumvire nubuzima bwubwenge, bityo bikazamura ubuzima bwo mumutwe nubuzima bwiza muri rusange.
Alpha-ketoglutarate-magnesium ni ihuriro ryibintu bibiri, muri byo alpha-ketoglutarate ni intera hagati ya cycle ya Krebs, igice cyingenzi cyubuhumekero. Ifite uruhare runini mu kubyara ingufu kandi igira uruhare muburyo butandukanye bwo guhinduranya. Magnesium ni minerval yingenzi igira uruhare mubikorwa byinshi bya physiologique, harimo kugabanya imitsi no kuruhuka. Ihuriro ryibi bice byombi byagaragaye ko bifite ingaruka nziza kumikorere ya myocardial contractile.
Ubushakashatsi bwasohotse mu kinyamakuru Cardiovascular Therapy bwakoze iperereza ku ngaruka za alpha-ketoglutarate-magnesium ku mikorere ya myocardial contractile imbeba. Abashakashatsi basanze inyongera ya alpha-ketoglutarate-magnesium yazamuye imikorere ya myocardial kwandura imbeba. Ihuriro ryibi bikoresho byabonetse kugirango byongere ubushobozi bwumutima bwo kwandura no kuruhuka, bityo bitezimbere imikorere yumutima muri rusange.
Abashakashatsi bavuze kandi ko inyongera ya alpha-ketoglutarate-magnesium yatumye kwiyongera kwa adenosine triphosphate (ATP) mu mitsi y'umutima. ATP nisoko yambere yingufu kubikorwa bya selile, harimo no kugabanya imitsi. Mu kongera urwego rwa ATP, Alpha-ketoglutarate-magnesium yongerera imbaraga umutima gukora kubyara ingufu zikenewe mumikorere ikwiye.
Ibisubizo by'ubu bushakashatsi byerekana ubushobozi bwa magnesium α-ketoglutarate nk'ubuvuzi butanga icyizere cyo kunoza imikorere ya myocardial. Ihuriro ryibi bikoresho byagaragaye ko byongera ingufu zingufu, kunoza imikorere ya calcium, kandi amaherezo byongera ubushobozi bwumutima bwo kwandura no kuvoma amaraso.
Byongeye kandi, imwe mu nyungu zingenzi za alpha-ketoglutarate-magnesium ni uruhare rwayo mu kubyara ingufu. AKG-Mg igira uruhare mu kuzunguruka aside aside, inzira y'ingenzi mu gukora adenosine triphosphate (ATP), isoko y'ibanze y'ingufu z'umubiri. Mugushyigikira iki gikorwa, AKG-Mg irashobora gufasha kongera ingufu zingufu, bigatuma iba amahitamo ashimishije kubantu bashaka kunoza imikorere yumubiri no kwihangana.
Usibye uruhare rwayo mu kubyaza ingufu ingufu, Alpha-ketoglutarate-magnesium yakozwe ku miterere ishobora kuba antioxydeant. Guhangayikishwa na Oxidative iterwa na radicals yubuntu irashobora gukurura ibibazo bitandukanye byubuzima, harimo gusaza imburagihe n'indwara zidakira. AKG-Mg irashobora gufasha gutesha agaciro radicals yubuntu no kugabanya kwangirika kwa okiside mumubiri, bigashyigikira ubuzima rusange nubuzima bwiza.
Birakwiye kuvuga ko alpha-ketoglutarate-magnesium yahujwe no gukira imitsi no gukora. Ubushakashatsi bumwe bwerekana ko kuzuza AKG-Mg bishobora gufasha kugabanya umunaniro wimitsi no kunoza imikorere ya siporo. Byongeye kandi, AKG-Mg irashobora gushyigikira kugarura imitsi iteza imbere poroteyine no kugabanya kwangirika kwimitsi nyuma yimyitozo ngororamubiri ikomeye.
Byongeye kandi, Alpha-ketoglutarate-magnesiumhas inyungu zishobora kumutima. Ibimenyetso bimwe byerekana ko AKG-Mg ishobora gufasha kugumana umuvuduko ukabije wamaraso no gushyigikira imikorere yumutima. Mugutezimbere umusaruro wa nitric oxyde na vasodilation, AKG-Mg irashobora gufasha kunoza amaraso nubuzima bwimitsi yumutima.
Hariho ibintu byinshi byingenzi ugomba gusuzuma muguhitamo alfa-ketoglutarate-magnesiumsupplement. Ubwa mbere, ugomba gushakisha inyongera zakozwe nibintu byiza-byiza. Ibi bivuze ko alpha-ketoglutarate na magnesium bikoreshwa mubyongeweho bigomba guturuka kubatanga isoko kandi bigakorerwa mubigo byubahiriza amahame akomeye yo kugenzura ubuziranenge. Byongeye kandi, urashobora gushaka gutekereza ku byongeweho byageragejwe nundi muntu, kuko ibi byemeza ko imbaraga nubuziranenge bwibicuruzwa byagenzuwe byigenga.
Usibye ubuziranenge bwibigize, ugomba no kwitondera urugero rwa alpha-ketoglutarate na magnesium mubyongeweho. Igipimo cyiza cyintungamubiri zirashobora gutandukana ukurikije ibyo ukeneye hamwe nintego zubuzima, bityo rero ni ngombwa kugisha inama inzobere mu buzima kugirango umenye dosiye ikwiye kuri wewe. Urashobora kandi gushaka gushakisha inyongeramusaruro zirimo ibindi bintu bihuza imbaraga, nka vitamine n'imyunyu ngugu, bishobora kurushaho kongera ingaruka za alpha-ketoglutarate na magnesium.
Suzhou Myland Pharm & Nutrition Inc. Yatangiye gukora ubucuruzi bwongera imirire kuva mu 1992. Nisosiyete ya mbere mu Bushinwa yateje imbere kandi igacuruza imbuto zinzabibu.
Hamwe nuburambe bwimyaka 30 kandi itwarwa nubuhanga buhanitse hamwe ningamba zinoze cyane R&D, isosiyete yateje imbere ibicuruzwa bitandukanye byapiganwa kandi ihinduka ubumenyi bwa siyanse yubuzima bushya, synthesis gakondo hamwe na serivise zikora inganda.
Byongeye kandi, isosiyete kandi ni uruganda rwanditswe na FDA, rwemeza ubuzima bwabantu bafite ireme rihamye kandi ryiterambere rirambye. Isosiyete R&D umutungo n'ibikoresho byo kubyaza umusaruro nibikoresho byisesengura nibigezweho kandi byinshi, kandi birashobora gukora imiti kuri miligarama kugeza kuri toni yubahiriza ibipimo bya ISO 9001 hamwe nuburyo bwo gukora GMP.
Ikibazo: Alpha-Ketoglutarate-Magnesium (AKG-Mg) ni iki?
Igisubizo: AKG-Mg nuruvange ruhuza alpha-ketoglutarate, intera hagati ya acide citricike, hamwe na magnesium, minerval yingenzi igira uruhare runini mubikorwa byinshi bya physiologiya.
Ikibazo: Ni izihe nyungu zishobora kubaho ku buzima bwa AKG-Mg?
Igisubizo: AKG-Mg yakozweho ubushakashatsi kubushobozi bwayo bwo gushyigikira ingufu, imikorere yimitsi, ubuzima bwimitsi yumutima, nibikorwa byubwenge. Irashobora kandi gufasha mubikorwa bya siporo no gukira.
Ikibazo: Nigute AKG-Mg ishyigikira umusaruro w'ingufu?
Igisubizo: AKG-Mg igira uruhare runini mukuzunguruka aside aside, niyo nzira ingirabuzimafatizo zitanga ingufu. Mugushyigikira iki gikorwa, AKG-Mg irashobora gufasha kongera ingufu ningufu.
Ikibazo: AKG-Mg irashobora gufasha mumikorere yimitsi?
Igisubizo: Ubushakashatsi bumwe bwerekana ko AKG-Mg ishobora gufasha kunoza imikorere yimikorere nimikorere, bigatuma ishobora kuba inyongera kubakinnyi nabantu bashaka gushyigikira imikorere yabo.
Inshingano: Iyi ngingo ni iyamakuru rusange gusa kandi ntigomba gusobanurwa nkinama zose zubuvuzi. Amwe muma poste yamakuru aturuka kuri enterineti kandi ntabwo ari umwuga. Uru rubuga rufite inshingano zo gutondeka, gutunganya no guhindura ingingo. Intego yo gutanga amakuru menshi ntabwo bivuze ko wemera ibitekerezo byayo cyangwa kwemeza ukuri kwibirimo. Buri gihe ujye ubaza inzobere mu buzima mbere yo gukoresha inyongeramusaruro cyangwa guhindura ibintu byubuzima bwawe.
Igihe cyo kohereza: Ukuboza-27-2023
