Gucukumbura Urolithin A na B: Kazoza ko Gutakaza Ibiro hamwe ninyongera zubuzima

Mu myaka yashize, icyerekezo cyibanze kuri urolithine, cyane cyane urolithine A na B, nkibintu bitanga ibyiringiro biva muri metabolism ya polifenol iboneka mu makomamanga nizindi mbuto. Izi metabolite zagiye zita ku nyungu zishobora kubaho ku buzima, harimo kugabanya ibiro, imiti irwanya gusaza, ndetse no kumererwa neza muri rusange.

Gusobanukirwa Urolithine: A na B.

Urolithine ni metabolite ikorwa na bagiteri yo mu nda iyo ivunaguye ellagitannine, ubwoko bwa polifenol iboneka mu mbuto zitandukanye, cyane cyane amakomamanga. Mu bwoko butandukanye bwa urolithine, urolithine A (UA) naurolithin B (UB) ni Byizwe cyane.

Urolithin A yahujwe ninyungu nyinshi zubuzima, harimo kunoza imikorere ya mitochondial, kuzamura imitsi, ningaruka zishobora kurwanya anti-inflammatory. Ubushakashatsi bwerekana ko UA ishobora kugira uruhare mu guteza imbere autofagy, inzira ifasha umubiri gukuraho ingirabuzimafatizo zangiritse no kuvugurura izindi nshya. Ubu bushobozi bwo kuvugurura burashimishije cyane cyane kubashaka kugumana imitsi nubuzima muri rusange uko basaza.

Ku rundi ruhande, Urolithin B, ntabwo yizwe cyane ariko ikekwa ko ifite inyungu zayo ku buzima. Ubushakashatsi bumwe bwerekana ko UB ishobora kandi gushyigikira imikorere ya mito-iyambere kandi ikagaragaza imiterere ya antioxydeant, nubwo ingaruka zayo zitanditse neza nkizya UA.

Urolithin A no Gutakaza ibiro

Kimwe mu bice bishimishije byubushakashatsi bukikije urolithine A ni uruhare rwayo mu kugabanya ibiro. Ubushakashatsi bwinshi bwerekanye ko UA ishobora gufasha kugenzura metabolism no guteza imbere ibinure. Kurugero, ubushakashatsi bwasohotse mu kinyamakuru * Kamere * bwabonye kourolithin A.irashobora kongera ubushobozi bwumubiri gutwika amavuta mugutezimbere imikorere ya mitochondial. Ibi ni ingenzi cyane kuko ubuzima bwa mitochondial ni ingenzi cyane kubyara ingufu na metabolism.

Byongeye kandi, urolithin A yerekanwe kugira ingaruka kuri mikorobe yo munda neza. Microbiome nzima ningirakamaro kugirango igogorwa ryiza na metabolism, kandi irashobora kugira uruhare runini mugucunga ibiro. Mugutezimbere ibidukikije byuzuye, UA irashobora gufasha abantu kugera kuntego zabo zo kugabanya ibiro neza.

Urolithin Yuzuye Inyongera

Hamwe no kwiyongera kwa urolithin A, ibigo byinshi byatangiye gutanga urolithine A yuzuye. Izi nyongera zicuruzwa nkuburyo bwo gukoresha inyungu zuru ruganda udakeneye kurya byinshi byamakomamanga cyangwa ibindi biribwa bikungahaye kuri ellagitannin.

Iyo usuzumye urolithine yuzuye Inyongera, ni ngombwa gushakisha ibicuruzwa bishyigikiwe nubushakashatsi bwa siyansi kandi byakorewe ibizamini bikomeye kugirango bisukure kandi bikore neza. Ibyongeweho byujuje ubuziranenge bigomba kuba birimo urugero rwa urolithine A kugirango barebe ko abakoresha bahabwa inyungu ziteganijwe.

Ibyiza bya Urolithin Inyongera ku Isoko

Mugihe icyifuzo cya urolithin A inyongera ziyongera, ibirango byinshi byagaragaye nkabayobozi kumasoko. Dore bimwe muribyiza urolithin A inyongera iraboneka:

1. Gukuramo amakomamanga hamwe na Urolithin A: Ibiranga bimwe bitanga inyongeramusaruro z'ikomamanga zirimo urolithine A nk'ibintu by'ingenzi. Ibicuruzwa bitanga inyungu zimbuto na metabolite zayo.

2.

Umwanzuro

Urolithin A na B byerekana ahantu hashimishije mubushakashatsi bufite ingaruka zikomeye kubuzima no kumererwa neza. Mugihe urolithine A yerekana amasezerano yo gushyigikira kugabanya ibiro nubuzima muri rusange, urolithin B nayo ishobora kugira uruhare muri izo nyungu, nubwo ku rugero ruto. Nkuko siyanse ikikije ibyo bikoresho ikomeza kugenda itera imbere, niko n'amahitamo aboneka kubaguzi bashaka kuzamura ubuzima bwabo binyuze mubyongeweho.

Kubashaka kumenya inyungu zishobora guterwa na urolithin A, ni ngombwa guhitamo inyongera zujuje ubuziranenge zishyigikiwe nubushakashatsi. Nkibisanzwe, abantu bagomba kugisha inama inzobere mu buvuzi mbere yo gutangira gahunda nshya y’inyongera, cyane cyane niba bafite ubuzima bwiza cyangwa bafata indi miti.

Muri make, urolithin A na B birenze amagambo yamagambo gusa mubikorwa byongera ubuzima; byerekana imipaka mishya mugusobanukirwa kwacu uburyo ibinyabuzima bishobora gufasha kugabanya ibiro, ubuzima bwimikorere, hamwe nubuzima bwiza muri rusange. Mugihe ubushakashatsi bukomeje kugenda bugaragara, dushobora gusanga nibindi byinshi bishimishije kuri izi metabolite zikomeye mumyaka iri imbere.