Izina ry'ubumenyi rya NAD ni nicotinamide adenine dinucleotide. NAD + ibaho muri buri selile yumubiri. Nibyingenzi metabolite na coenzyme munzira zitandukanye. Ihuza kandi ikagira uruhare mubikorwa bitandukanye byibinyabuzima. Enzymes zirenga 300 ziterwa na NAD + Gukora. Ariko, urwego rwibirimo rwa NAD + ntabwo ruhagaze. Mugihe tugenda dusaza, ibiri muri NAD + muri selile bizagabanuka. Cyane cyane nyuma yimyaka 30, urwego rwa NAD + ruzagabanuka cyane, biganisha ku kugabanuka kwimirimo myinshi bityo bikagaragaza ibimenyetso byubusaza. Nikotinamide riboside chloride ni ubwoko bwa vitamine B3. Nikotinamide riboside chloride irashobora guhinduka muri NAD + (nicotinamide adenine dinucleotide). Nimwe mubize cyane NAD + ibanziriza. Biroroshye kwinjizwa numubiri no gukoresha. Ubushakashatsi bwinshi bwerekanye ko kuzuza NRC bishobora kongera urwego rwa NAD +, ari nabwo rushobora kuzana inyungu kuri sisitemu ya metabolike, umutima-mitsi na nervice. Bikunze gukoreshwa nkibiryo byokurya kugirango biteze imbere ubuzima bwiza muri rusange.
Nikotinamide riboside chloride (NRC) ikomoka kuri vitamine B3 nibintu bishya bya bioactive. Igizwe na molekile isukari ya ribose hamwe na vitamine B3 igizwe na nikotinamide (izwi kandi nka acide nicotinike cyangwa vitamine B3). Irashobora gukoreshwa binyuze mu kurya inyama, amafi, ibinyampeke nibindi biribwa cyangwa binyuze muri NRC.
Nikotinamide ribose chloride irashobora guhinduka muri NAD + (nicotinamide adenine dinucleotide) hanyuma igakora ibikorwa byibinyabuzima muri selile. NAD + ningirakamaro ya coenzyme idasanzwe igira uruhare muburyo butandukanye bwimikorere ya selile, harimo kubyara ingufu, gusana ADN, gukwirakwiza selile, nibindi. Mugihe cyo gusaza kwumubiri wumuntu, ibirimo NAD + bigenda bigabanuka buhoro buhoro. Nicotinamide riboside ya chloride yiyongera irashobora kongera urwego rwa NAD +, bikaba biteganijwe ko bizadindiza kugaragara kwabasaza nindwara zifitanye isano.
Ubushakashatsi kuri nicotinamide riboside chloride bwerekanye ko bufite ibikorwa byinshi byibinyabuzima, nka:
Kunoza ingufu za metabolism, kongera kwihangana no gukora imyitozo;
Kunoza imikorere ya neurologiya no kwibuka;
Kunoza imikorere yumubiri.
Muri rusange, nicotinamide riboside chloride ningirakamaro cyane yintungamubiri kandi ifite ibyifuzo byinshi.
Byongeye kandi, nicotinamide ribose chloride nayo ikoreshwa cyane mubushakashatsi bwa siyansi. Nkibintu byabanjirije NAD +, birashobora gukoreshwa mukwiga biosynthesis ninzira ya metabolike ya NAD + nibindi bibazo bifitanye isano. Muri icyo gihe, nicotinamide riboside ya chloride nayo ikoreshwa nkibigize ibicuruzwa byubuzima no kwisiga kugirango biteze imbere ingirabuzimafatizo no kugabanya gusaza kwuruhu.
Gusaza ni ingingo ihoraho kubantu. Nk’uko ubushakashatsi bwakozwe n’abahanga bubitangaza, gusaza kw ingirabuzimafatizo bifitanye isano rya bugufi no kugabanya ibirimo nicotinamide adenine dinucleotide (NAD). NAD ni ihurizo ryingenzi muri metabolism no gusana ingirabuzimafatizo mumubiri wumuntu. Ntishobora kudindiza gusaza gusa, ahubwo irashobora no gukomeza ubuzima bwimikorere no gukomeza ubuzima bwumubiri nubwenge. ariko. Mugihe tugenda dusaza, urwego rwa NAD mumibiri yacu rugabanuka vuba kandi vuba, ndetse rushobora no kugabanuka kurenza kimwe cya kabiri hagati yimyaka 40 na 80.
Hariho umusemburo w'ingenzi mu mubiri wacu, akaba aribwo shingiro ry'ingirabuzimafatizo ya metabolism. Ni kangahe? Inzira hafi ya zose zigumana imikorere isanzwe yumubiri, nka metabolism, gusana, nubudahangarwa, bisaba uruhare rwiyi misemburo. Iyo urwego rwiyi misemburo rugabanutse, byinshi mubimenyetso nindwara zijyanye no gusaza birashobora gukurikiraho, nkindwara ziterwa na metabolike, intege nke zumubiri, kugabanuka kwubwenge, nibindi. Iyi misemburo yingenzi ifite izina rirerire: nicotinamide adenine dinucleotide, cyangwa NAD +.
Muri make, kugabanuka kwa NAD + mumubiri bisobanura gusaza. Noneho, dushobora kongera NAD + kumubiri kugirango dutinde gusaza? Niba wongeyeho NAD + mu buryo butaziguye, umubiri wumuntu ntushobora kuwunyunyuza, kandi bizagira ingaruka zikomeye. Kubwibyo, abantu bahanze amaso kubintu byabanjirije NAD +: nicotinamide ribose chloride (NRC).
Nikotinamide riboside chloride nuburyo bwa vitamine B3 nimwe mubushakashatsi bwakozwe na NAD + bwibanze. Biroroshye kwinjizwa no gukoreshwa numubiri. Ubushakashatsi bwinshi bwerekanye ko kuzuza NR bishobora kongera urwego rwa NAD +, ari nabwo rushobora kuzana inyungu kuri sisitemu ya metabolike, umutima-mitsi na nervice.
Ijambo "kurwanya gusaza" ribona rap mbi. Birasa nkaho tugerageza guhagarika ikintu kimaze gutera imbere, cyangwa ntidushobora kwakira ibice byacu tugomba gukunda. Ariko ikigaragara ni uko impinduka za metabolike zibaho munsi yuruhu mbere yuko tubona ingaruka zo gusaza. Guhitamo kwegera ubuzima bwacu bivuye imbere birashobora kuba aribyo dukeneye kugirango tunonosore uburyo dusaza.
Mubyukuri, kimwe mu biranga gusaza ni inzira izwi nka "imikorere mibi ya mitochondrial," ijambo ryerekeza ku gutakaza imbaraga muri rusange no gukora neza kwingirabuzimafatizo zacu mugihe runaka. Iyi ishobora kuba imwe mumpamvu zituma dusaza. Niba mitochondriya ari yo ntandaro yo gusaza kwacu, birakwiye ko dukora ubushakashatsi muburyo bwose bushoboka kugirango bakomeze gukora igihe kirekire gishoboka.
Wige ibijyanye na mitochondria.
Imbere mu ngirabuzimafatizo hafi ya zose harimo utugingo ngengabuzima duto duto, bita mitochondria - “imbaraga z'akagari.” Izi ngingo nto zifite inshingano zo gutanga 90% yingufu umubiri wacu ukeneye. Mitochondriya niyo mpamvu tubaho muri iki gihe nk'inyamaswa zigoye aho kuba bagiteri.
Ntabwo buri gihe tuzi akamaro ka mitochondriya ifite akamaro kubuzima bwacu. Inzira yingenzi kugirango mitochondriya yawe igire ubuzima bwiza ni molekile yitwa NAD + (nicotinamide adenine dinucleotide). Ingirabuzimafatizo zacu zisanzwe zitanga NAD + kandi turazikoresha umunsi wose.
Turabizi kandi ko gutanga kwa NAD + kugabanuka uko dusaza. Abashakashatsi bamaze kubona ko NAD + ishobora gufata urufunguzo rwo gukomeza ingirabuzimafatizo zacu, barihutira gushaka uburyo bwo kuyikoresha neza.
Abashakashatsi basanzwe bazi ko vitamine ebyiri zitangira inzira yimiti yo kongera NAD +: niacin na niacinamide. Ibi byavumbuwe mu 1930 kugirango bivure pellagra, vitamine B3 ishobora guhitana abantu.
Niacin kandi yakomeza kuba umuti wa cholesterol nyinshi muri 1950. Nyamara, byagaragaye ko kunywa urugero rwinshi rwa niacin bishobora rimwe na rimwe gutera uruhu rutera uruhu rutera uburakari kandi butagaragara.
Niacinamide ntabwo itera uruhu kandi rushobora gutanga inyungu nyinshi zimwe, ariko irabuza gukora proteine zingenzi zo gusana ingirabuzimafatizo zitwa sirtuins. Ari niacinamide cyangwa niacin ntabwo byagize akamaro nkuko abashakashatsi babitekerezaga.
Nubwo vitamine zombi ari NAD + ibanziriza, ntabwo ari igisubizo cyiza. Bitewe n'ingaruka mbi za niacin hamwe nikigereranyo cya nicotinamide, abashakashatsi baracyafite vitamine nziza ihagije kugirango bongere urwego rwa NAD +.
Ubuvumbuzi bwa nicotinamide riboside.
Ubundi buryo bwa vitamine B3 yitwa nicotinamide riboside yavumbuwe mu musemburo mu 1940. Ariko mu ntangiriro ya za 2000 ni bwo abahanga batangiye kubona ubushobozi bwa vitamine ya gatatu, B3, kugira ngo itongera NAD + gusa ahubwo inatezimbere ubuzima bw’abantu. Mu 2004, itsinda ry’ubushakashatsi bwa Dartmouth College ryavumbuye ko nicotinamide riboside, kimwe na murumuna wa vitamine B3, ibanziriza NAD +.
Itsinda ry’ubushakashatsi riyobowe na Dr. Charles Brenner ryasanze nicotinamide riboside yongera NAD + mu mbeba, kandi imbeba zagize inyungu nyinshi ku buzima.
Imbeba zerekanaga ibintu byose uhereye kumasukari yamaraso meza hamwe na cholesterol kugeza kugabanuka kwangirika kwimitsi no kurwanya ibiro. Muganga Charles Brenner yasanze ibisubizo bishimishije kuburyo yateye intambwe ikurikira kugirango yumve ingaruka za nicotinamide riboside ku buzima bwabantu.
Muri 2014, Dr. Brenner abaye umuntu wa mbere wafashe nikosinamide riboside nk'inyongera. Ibisubizo birashimishije. Ubu buryo butazwi bwa vitamine B3 bwongereye cyane urwego rwa NAD + umutekano, vuba, kandi nta ngaruka mbi.
Nikotinamide riboside ikoresha inzira idasanzwe yo kubyara NAD + ntayindi vitamine B3 ikoresha.
Nikotinamide riboside irashobora kandi gukora ingirabuzimafatizo zo gusana poroteyine sirtuins. Mugihe tugenda dusaza, iyi sirtuins ikora amasaha y'ikirenga kugirango ifashe selile gukomeza gukomera.
Kugumana ubuzima bwiza uko usaza ntabwo bizigera byoroha nka vitamine imwe, kabone niyo imwe itanga ikizere nka nicotinamide riboside. Hariho ubushakashatsi burenga 100 bukora iperereza kuri nicotinamide riboside, inyinshi murizo zerekana ko kwiyongera kwa NAD + bifitanye isano nubuzima bwimitsi n'imitsi mu mbeba. Ubushakashatsi bw'inyongera burakomeje kugira ngo wumve uruhare rwa NAD + mu gushyigikira izindi mbogamizi z’ubuzima zijyanye n’imyaka, harimo kugabanuka kw imikorere yumwijima, kongera ibiro, urugero rwa insuline ndetse nubwonko bwimbeba.
NAD ni iki?
NAD + ni coenzyme I, ikaba ari coenzyme yohereza proton (mubyukuri, ion hydrogène) kandi ikagira uruhare mubikorwa byinshi bya physiologique nka metabolism material selile, synthesis, hamwe no gusana ADN. NAD + ni intungamubiri zikenewe mu mikorere ya poroteyine ya Sirtuin, ibyo bita "kuramba" n'abahanga. By'umwihariko, irashobora kugumana uburebure bwa telomereri yingenzi, kugabanya umuvuduko wo gusaza no kongera igihe.
NAD + irashobora kandi guteza imbere gusana gene no gutinda gusaza kwa selile. NAD + iteza imbere ingirabuzimafatizo kandi ikarwanya indwara z'umubiri. NAD + itezimbere chromosome kandi igabanya ibyago bya kanseri.
Ninshuti nziza za enzymes, zifasha gukongeza "imashini ya selile" itanga imbaraga zikenewe mumirimo yose ikomeye mumubiri wawe kurwego rwa selire.
Kuki NAD + ari ngombwa?
Bitewe n'uruhare runini mu gutanga ingufu za selile, kubura NAD + mumubiri wawe bituma imirimo myinshi yumubiri ntacyo imaze. Hatari NAD, ibihaha byawe ntibishobora gufata ogisijeni, umutima wawe ntushobora kuvoma amaraso, kandi synapses yubwonko bwawe ntishobora gucana.
NAD + ifasha kandi guteza imbere gusana ADN no kugenzura ibikorwa by'utugari dukorana na sirtuins na poly (ADP-ribose) polymerase (PARPs), zikaba ari ingenzi mu kugenzura ibisubizo by'utugari ku bitutsi nko kurya cyane, kunywa inzoga, guhagarika ibitotsi, ndetse no kwicara. Enzymes.
NAD + no gusaza
Ubushakashatsi bwakozwe mu mwaka wa 2012 n'itsinda ryaturutse mu ishami rya Farumasi muri kaminuza ya New South Wales ryerekanye ko metabolism ya NAD ifitanye isano n'imyaka. Ubushakashatsi bwerekana ko urwego rwa NAD + mu ngingo z’uruhu rw’umuntu rugabanuka kugera kuri 50% hagati y’imyaka 40 na 60, kandi ko kugabanuka kwa NAD + bishobora kugira uruhare runini mu gusaza.
Abashakashatsi bagize bati: "Isano rikomeye ryagaragaye hagati y'urwego rwa NAD + n'imyaka ku bagabo no ku bagore."
Byongeye kandi, NAD igira uruhare mu guhumeka selile, cyane cyane muri mitochondriya, kandi ikagira uruhare mu buzima rusange bwa mito-iyambere. Hariho ubumenyi bukomeye bwa siyanse mu ruhare rwa NAD mu mikorere mibi ya mitochondrial, kimwe mu biranga gusaza.
Mu myaka yashize, ubushakashatsi bwibanze ku gusobanukirwa uruhare rwa NAD mugukemura iyi mikorere ijyanye nimyaka.
Nikotinamide Ribose Chloride yongerera NAD + urwego.
NR ibanziriza NAD, bivuze ko ari "inyubako yubaka" aho molekile ya NAD + ikorerwa. Yavumbuwe mu 2004 nka vitamine ibanziriza NAD +, bituma iba imwe mu ntambwe zigezweho mu bushakashatsi bwa NAD +.
NR ni vitamine isanzwe iboneka hamwe nuburyo bushya bwa vitamine B3, ariko kuyikoresha nk'inyongera byagize ingaruka mbi kuri vitamine "gusaza neza". Nibyiza cyane mukwongera NAD, bigatuma iba imwe mubikorwa bishimishije mubisubizo byubusaza bwiza.
NR irashobora kongera neza urwego rwa NAD +. Ikigeragezo kivura cyasohotse muri Scientific Reports cyerekanye ko cyiyongereye NAD + kugera kuri 50% nyuma yibyumweru bibiri cyo kuyifata.
Nubwo ibyongeweho bya NR byagaragaye mubuvuzi byongera urwego rwa NAD +, inyongera ya NAD + nkibigize ibintu ntabwo ari byiza.
NAD + ni molekile nini cyane kandi ntishobora kwinjira muri selile. Ahubwo, umubiri wawe ugomba kubigabanyamo ibice bito mbere yuko byambuka ingirabuzimafatizo. Ibi bice byongeye guteranyirizwa imbere muri bateri.
Nikotinamide riboside (NR) na nicotinamide riboside chloride (NRC) ni uburyo bwombi bwa vitamine B3, izwi kandi nka niacin. Vitamine B3 nintungamubiri zingenzi zigira uruhare runini mumikorere itandukanye yumubiri, harimo kubyara ingufu, gusana ADN, hamwe na metabolism selile. NR na NRC byombi nibibanziriza nicotinamide adenine dinucleotide (NAD +), coenzyme igira uruhare mubikorwa bitandukanye byibinyabuzima, nko kugenzura ingufu za selile no gushyigikira gusana ADN.
Nikotinamide riboside (NR) ni ubwoko bwa vitamine B3 imaze kwitabwaho kubera imbaraga zayo zo kurwanya gusaza no kongera ingufu. Nibisanzwe biboneka mubisanzwe biboneka mubiribwa bimwe na bimwe, ariko biranaboneka nkinyongera yimirire. NR izwiho ubushobozi bwo kongera urwego rwa NAD + mu mubiri, ari nabwo rushobora gushyigikira imikorere ya mito-iyambere, kongera ingufu za selile, kandi rushobora kurinda uburinzi bugabanuka.
Ku rundi ruhande, Nikotinamide riboside chloride (NRC), ni uburyo bw'umunyu wa NR kandi bukunze gukoreshwa mu byongera ibiryo. Kongera chloride muri NR bitanga NRC, bizera ko bizamura urwego rwimibereho hamwe na bioavailability. Ibi bivuze ko NRC ishobora kugira uburyo bwiza bwo kwinjiza no gukoresha mumubiri kuruta NR yonyine kandi ishobora kugira ingaruka zigaragara kurwego rwa NAD + n'imikorere ya selile.
Kimwe mubitandukaniro nyamukuru hagati ya NR na NRC nuburyo bwabo bwimiti. NR nuburyo bwibanze bwuru ruganda, mugihe NRC ni verisiyo yahinduwe hiyongereyeho chloride. Iri hinduka rigamije kongera imbaraga zo gukomera hamwe na bioavailable, byorohereza umubiri kubyakira no kubikoresha.
Ukurikije inyungu zabo zishobora guteza ubuzima, NR na NRC batekereza ko bifite ingaruka zisa bitewe nubushobozi bwabo bwo kwiyongeraNAD +urwego. Izi ngaruka zishobora kuba zirimo imikorere ya mito-iyambere, kongera imbaraga za metabolism, hamwe nubufasha bushobora kubaho mubuzima rusange. Ariko, gukoresha NRC mubyongeweho birashobora kuzana inyungu yinyongera yo kwinjiza neza no kuyikoresha, birashoboka ko byavamo inyungu zigaragara ugereranije no gukoresha NR wenyine.
1. Kongera ingufu zingirabuzimafatizo
Imwe mu nyungu zigaragara zanicotinamide riboside chloride ni uruhare rwayo mu kuzamura ingufu za selile. NR niyo ibanziriza nicotinamide adenine dinucleotide (NAD +), coenzyme igira uruhare mukubyara adenosine triphosphate (ATP), ifaranga ryibanze ryingirabuzimafatizo. uruhare rukomeye. Mugihe tugenda dusaza, urwego rwa NAD + rugabanuka, bigatuma ingufu za selile zigabanuka. Hiyongereyeho NR, byizerwa ko urwego rwa NAD + rushobora kuzuzwa, bityo bigashyigikira ingufu za selile nziza.
2. Imikorere ya mitochondrial nigihe cyo kubaho
Mitochondria ni imbaraga zingirabuzimafatizo, ishinzwe kubyara ingufu no kugenzura imikorere ya selile. Ubushakashatsi bwerekana ko Nikotinamide Riboside Chloride ishobora gushyigikira imikorere ya mito-iyambere mu guteza imbere biogenezi ya mitochondriya nshya no kongera imikorere yayo. Ibi bifite ingaruka mubuzima rusange no gusaza neza, kimwe na mitochondriya ikora neza ningirakamaro mukubungabunga ubuzima bwimikorere no kwihangana.
3. Ubuzima bwa metabolike no gucunga ibiro
NAD + ni coenzyme, cyangwa molekile yinyongera, igira uruhare mubitekerezo byinshi byibinyabuzima. Ubushakashatsi buherutse gukorwa bwagaragaje ko kuzuza nicotinamide ribose bishobora gutera imbaraga za metabolism NAD + kubantu bakuze bafite imyaka yo hagati ndetse nabakuze. Ntabwo inyongera za NR zihanganirwa gusa nabitabiriye amahugurwa, zishobora kuba zarafashije kugabanya umuvuduko wamaraso no gukomera kwa arterial. Kubura NAD + nimpamvu nyamukuru itera gusaza n'indwara nyinshi, kandi ubushakashatsi bwerekana ko kugarura urwego rwa NAD + bifite agaciro gakomeye ko kuvura no kurya.
Mugukomeza urwego rwa NAD +, nicotinamide ribose yunguka kugenga metabolike, kubika ingufu, synthesis ya ADN, nibindi bikorwa byumubiri.
Byongeye kandi, ubushakashatsi bwerekanye ko inyongera ya NR ishobora kunoza insuline, kugabanya umuriro, no kongera imiterere ihindagurika. Izi ngaruka zishobora kugirira akamaro cyane abantu bashaka kugenzura ibiro byabo no gushyigikira ubuzima bwimikorere.
4. Imikorere yubwenge nubuzima bwubwonko
Nkibibanziriza NAD +, nicotinamide ribose irinda ingirabuzimafatizo zubwonko guhagarika umutima, bishobora gutera indwara zubwonko ziterwa nimyaka. Mu ngirabuzimafatizo z'ubwonko, NAD + ifasha kugenzura umusaruro wa PGC-1-alpha, poroteyine igaragara ifasha kurinda ingirabuzimafatizo imbaraga za okiside ndetse n'imikorere mibi ya mito-iyambere.
Abashakashatsi basanze mu mbeba, NAD + depletion igira uruhare runini mu gutera indwara ya neuroinflammation, kwangiza ADN, no kwangirika kw'imitsi mu ndwara ya Alzheimer. Mu bushakashatsi bwakozwe na test-tube, nicotinamide riboside yazamuye urwego rwa NAD + kandi inoza imikorere ya mito-iyambere mu ngirabuzimafatizo z'abarwayi ba Parkinson.
Ubushakashatsi bugaragara kandi bwerekana inyungu zishobora guterwa na nicotinamide riboside chloride. NAD + igira uruhare mubikorwa bitandukanye bijyanye n'ubuzima bw'ubwonko, harimo ibimenyetso bya neuronal, gusana ADN, no gukuraho poroteyine zangiritse. Mugushyigikira urwego rwa NAD +, NR irashobora gufasha gukomeza imikorere yubwenge no kwirinda kugabanuka kwimyaka.
5. Imikino ngororamubiri no gukira
Ubushakashatsi bwakozwe mu mwaka wa 2019 bwasohotse mu kinyamakuru cy’iburayi cy’intungamubiri zerekanye ko gukoresha nicotinamide ribose inyongera byongera ubumenyi bw’umubiri kandi bikagabanya imbaraga za okiside ku bantu bakuze.
Abashakashatsi banzuye ko inyongera ya NR yagiriye akamaro abantu babuze NAD +, basobanura impamvu byagize ingaruka nziza kubantu bakuze kurusha abakuze bato.
Abakinnyi n’abakunzi ba fitness barashobora gushimishwa no kumenya ko nicotinamide riboside chloride ishobora kugira ingaruka nziza mubikorwa bya siporo no gukira. NAD + igira uruhare runini mugutunganya imikorere ya selile igira uruhare mukubyara ingufu n'imikorere y'imitsi. Mugushyigikira urwego rwa NAD +, NR irashobora kongera kwihangana, kunoza imitsi, no kuzamura imikorere muri rusange.
Ubwiza n'Ubuziranenge
Mugihe uguze nicotinamide riboside ya chloride ifu, ubuziranenge nubuziranenge bigomba kuba ibyawe byambere. Shakisha ibicuruzwa byakozwe namasosiyete azwi hamwe nundi muntu wageragejwe kubwera nimbaraga. Byiza, ibicuruzwa bigomba kuba bitarimo umwanda hamwe nuwuzuza kugirango umenye neza ko wongeyeho inyongera-nziza itanga inyungu ziteganijwe.
Imikoreshereze n'imikoreshereze
Mbere yo gushyiramo ifu ya nicotinamide riboside ya chloride muri gahunda yawe ya buri munsi, ni ngombwa kumva neza dosiye nubuyobozi bukoreshwa. Ni ngombwa gutangirira ku kigero cyo hasi hanyuma ukiyongera buhoro buhoro nkuko bikenewe, kuko dosiye ndende ntabwo byanze bikunze bingana ibisubizo byiza kandi bishobora gutera ingaruka mbi. Byongeye kandi, nyamuneka tekereza kugisha inama inzobere mu by'ubuzima kugirango umenye igipimo cyiza ku ntego zawe z'ubuzima n'ibikenewe.
Inyungu zishobora gutekerezwa
Ifu ya Nikotinamide Riboside Chloride Powder ikunze kuvugwa kubera inyungu zishobora kuba, harimo gushyigikira urwego rwingufu, imikorere ya mito-iyambere, hamwe nubuzima rusange. Ubushakashatsi bwerekana ko bushobora no kugira ingaruka ku gusaza n'indwara ziterwa n'imyaka.
Umutekano no kwirinda
Kimwe ninyongera iyo ari yo yose, ni ngombwa gushyira imbere umutekano no kumva ingamba zishobora kwitabwaho. Nubwo nicotinamide riboside chloride yihanganira muri rusange, abantu bamwe bashobora kugira ingaruka zoroheje, nko kubura gastrointestinal. Ikigeretse kuri ibyo, niba ufite ubuzima bwihishe inyuma cyangwa urimo gufata imiti, menya neza kubaza inzobere mu by'ubuzima mbere yo gukoresha iyi nyongera kugirango urebe ko ifite umutekano kandi ikwiranye n’ibibazo byawe bwite.
Hitamo isoko ryiza
Iyo uguze ifu ya Nicotinamide Riboside Chloride, ni ngombwa guhitamo isoko ryiza rishyira imbere ubuziranenge, gukorera mu mucyo, no guhaza abakiriya. Shakisha ibigo bitanga ibisobanuro birambuye kubikorwa byabo byo gukora, amasoko, hamwe no kwipimisha kubandi. Byongeye kandi, tekereza gusoma ibyifuzo byabakiriya no gushaka ibyifuzo biva ahantu hizewe kugirango umenye ko ugura kubitanga byizewe kandi byizewe.
Suzhou Myland Pharm & Nutrition Inc yatangiye gukora ubucuruzi bwongera imirire kuva mu 1992. Nisosiyete ya mbere mu Bushinwa yateje imbere kandi igacuruza imbuto zinzabibu.
Hamwe nuburambe bwimyaka 30 kandi itwarwa nubuhanga buhanitse hamwe ningamba zinoze cyane R&D, isosiyete yateje imbere ibicuruzwa bitandukanye byapiganwa kandi ihinduka ubumenyi bwa siyanse yubuzima bushya, synthesis gakondo hamwe na serivise zikora inganda.
Mubyongeyeho, Suzhou Myland Pharm & Nutrition Inc nayo ikora FDA yemewe. Ibikoresho bya sosiyete R&D, ibikoresho byububiko, nibikoresho byisesengura nibigezweho kandi bikora kandi birashobora gukora imiti kuva kuri miligarama kugeza kuri toni mubipimo, kandi ikubahiriza ibipimo bya ISO 9001 nibisobanuro byakozwe na GMP.
Ikibazo: Ifu ya nicotinamide riboside ya chloride ni iki?
Igisubizo: Ifu ya Nicotinamide Riboside Chloride ni ubwoko bwa vitamine B3 yakozweho ubushakashatsi kubushobozi bwayo bwo gushyigikira ingufu za selile na metabolism. Bikunze gukoreshwa nkibiryo byokurya kugirango biteze imbere ubuzima bwiza muri rusange.
Ikibazo: Ni izihe nyungu zishobora guterwa nifu ya nicotinamide riboside ya chloride?
Igisubizo: Inyungu zimwe zishobora kuba za Nikotinamide Riboside Chloride Powder zirimo gushyigikira imikorere ya mito-iyambere, guteza imbere gusaza neza, no kongera kwihangana no gukora kumubiri. Irashobora kandi gufasha gushyigikira imikorere yubwenge hamwe nubuzima rusange bwimikorere.
Ikibazo: Ni he nshobora kugura ifu ya nicotinamide riboside ya chloride?
Igisubizo: Ifu ya Nicotinamide Riboside Chloride iraboneka kubacuruzi batandukanye no mububiko bwa interineti. Mugihe uguze iyi nyongera, ni ngombwa guhitamo isoko izwi kugirango wizere ubuziranenge n'umutekano.
Inshingano: Iyi ngingo ni iyamakuru rusange gusa kandi ntigomba gusobanurwa nkinama zose zubuvuzi. Amwe muma poste yamakuru aturuka kuri enterineti kandi ntabwo ari umwuga. Uru rubuga rufite inshingano zo gutondeka, gutunganya no guhindura ingingo. Intego yo gutanga amakuru menshi ntabwo bivuze ko wemera ibitekerezo byayo cyangwa kwemeza ukuri kwibirimo. Buri gihe ujye ubaza inzobere mu buzima mbere yo gukoresha inyongeramusaruro cyangwa guhindura ibintu byubuzima bwawe.
Igihe cyo kohereza: Kanama-14-2024
