Kugeza ubu, hari inyongera zitabarika ku isoko, buriwese asezeranya kuzamura ubuzima bwawe muburyo bumwe. Hamwe namahitamo menshi yo guhitamo, kumenya inyongera nibyiza kumigambi yawe yubuzima irashobora kuba myinshi. Niba kuzamura ubuzima bwawe muri rusange aricyo kintu cyibanze cyawe, noneho urashobora gushaka gutekereza kongeramo deazaflavin kumikorere yawe ya buri munsi. Deazaflavin ni uruganda rusanzwe rwerekanwe ko rufite inyungu nyinshi mubuzima, harimo kuzamura ubuzima bwimitsi yumutima, kongera ingufu, no gushyigikira ubuzima muri rusange.
Deazaflavin, izwi kandi nka 5-deazaflavin, ifite imiterere isa na flavin, ariko imiterere yimiti yarahindutse ugereranije na flavin isanzwe. Iri hinduka ririmo kuvanaho atome ya azote mu mpeta ya flavin, bikavamo "denitrified" (bisobanura "kubura azote") molekile ya flavin. Ihinduka ritanga deazaflavin imiterere yihariye ya chimique itandukanya nizindi flavine. Ubushakashatsi bwerekanye ko 5-deazaflavin ishobora kubyara imbaraga-nke-5-deazaflavin radicals yubusa imbere yumunezero mwinshi hamwe nabaterankunga ba electron (nka alcool, amine, nibindi).
Imwe mu zizwi cyane za deazaflavin ni riboflavin (vitamine B2), intungamubiri zingenzi zigira uruhare runini mu kubyara ingufu z'umubiri no guhindagurika. Riboflavin ni yo ibanziriza coenzyme flavin mononucleotide (FMN) na flavin adenine dinucleotide (FAD), igira uruhare mu myitwarire itandukanye, cyane cyane uburyo bwo gutwara ibintu bya elegitoronike yo guhumeka. Kubwibyo, riboflavin nibiyikomokaho nibyingenzi mukubungabunga ubuzima nubuzima muri rusange.
Inyongera ya Deazaflavin ni imvange hamwe na antioxydeant na anti-inflammatory, bigatuma ishobora gutera imbaraga mubuzima rusange no kumererwa neza. Izi nyongera zitekereza ko zifasha kongera urwego rwingufu, gushyigikira metabolisme nzima, no guteza imbere ubuzima bwumutima.
Imwe mu nyungu zingenzi zinyongera za deazaflavin nubushobozi bwabo bwo kurwanya stress oxydeide mumubiri. Guhangayikishwa na Oxidative bibaho mugihe habaye ubusumbane hagati ya radicals yubusa na antioxydants mu mubiri, bigatera kwangirika kwingirabuzimafatizo.
Deazaflavins nicyiciro cyibintu byubatswe bijyanye na riboflavin (izwi kandi nka vitamine B2). Izi nteruro zigira uruhare runini mubikorwa bitandukanye byo guhinduranya, harimo no gukora adenosine triphosphate (ATP), isoko nyamukuru yingirabuzimafatizo. Byizerwa ko inyongera za deazaflavin zongera umusaruro wa ATP mugushyigikira imikorere yimisemburo yingenzi igira uruhare mu guhinduranya ingufu.
Inyongera ya Deazaflavins ifite ubushobozi bwo kuzamura imikorere ya mito-iyambere. Mitochondriya ni imbaraga z'akagari kandi ishinzwe kubyara ATP binyuze muri fosifori ya okiside. Deazaflavin yerekanwe kongera imikorere yiki gikorwa, bityo kongera ingufu zingufu no kunoza imikorere yutugari. Bivugwa ko Deazaflavin yikuramo radicals yubusa kandi ikagabanya kwangiza okiside, bityo bigatuma gusaza neza no kugabanya ibyago byindwara ziterwa nimyaka.
Byongeye kandi, inyongera za deazaflavin zabonetse kugirango zihindure ibikorwa bya sirtuins, umuryango wa poroteyine zigira uruhare mu kugenzura metabolisme selile, gusana ADN, no gukemura ibibazo. Sirtuins izwiho kugira uruhare runini mugusaza kandi ibikorwa byabo birashobora guterwa nibintu bitandukanye, harimo na deazaflavin. Mugukoresha enzymes ya sirtuin, inyongera ya deazaflavin irashobora guteza imbere kuramba nubuzima muri rusange.
Deazalavin, izwi kandi nka riboflavin 5-deazaflavin, ni ubwoko bwa vitamine B2 ari ngombwa mu kubungabunga ubuzima muri rusange. Ifite uruhare runini mukubyara ingufu, metabolism, no kubungabunga ubuzima bwuruhu, ijisho, na nervice. Deazalavin ikunze kuboneka mubiribwa nkamata, amagi, inyama, nimboga rwatsi rwatsi, kandi iraboneka muburyo bwinyongera kubantu bashobora kubura cyangwa bashaka kunoza urwego rwabo.
Ku rundi ruhande, NMN, ikomoka kuri niacine, izwi kandi nka vitamine B3, kandi ibanziriza nicotinamide adenine dinucleotide (NAD +), coenzyme igira uruhare mu ngirabuzimafatizo zitandukanye, harimo gukora ingufu, gusana ADN no kwerekana gene. NMN yitabiriwe n'abantu benshi kubera ingaruka zayo zo kurwanya gusaza, kuko byagaragaye ko yongera urugero rwa NAD + mu ngingo zitandukanye kandi ikaba yarajyanye no kunoza imikorere ya metabolike no kuzamura ubuzima mu bushakashatsi bw’inyamaswa.
None, ni irihe tandukaniro riri hagati ya Deazaflavin na NMN? Kimwe mubitandukaniro nyamukuru nukuntu bakora mumubiri. Igikorwa nyamukuru cya Deazaflavin ni nka coenzyme, ifasha mukubyara ingufu na metabolism, mugihe NMN ibanziriza NAD +, igira uruhare runini mumikorere ya selile kandi ifitanye isano no gusaza. Ikigeretse kuri ibyo, ibice byombi bifite imiterere yimiti itandukanye kandi itunganywa muburyo butandukanye mumubiri, hamwe na NMN niyo ibanziriza NAD +.
Ku bijyanye n’inyungu zishobora kubaho, Deazaflavin na NMN bombi bahujwe no kuzamura urwego rw’ingufu n’imikorere ya metabolike, ibyo bikaba bishobora kugirira akamaro cyane abantu bashaka gushyigikira ubuzima n’ubuzima muri rusange. Nyamara, ingaruka NMN ishobora kurwanya yo gusaza yatumye irushaho gukundwa, kuko ubushakashatsi bwerekana ko kongera urwego rwa NAD + bishobora gufasha kugabanya igabanuka rishingiye ku myaka no kuramba.
Guhitamo hagati ya Deazaflavin na NMN birashobora guterwa nintego zubuzima kugiti cye. Kubashaka cyane cyane gushyigikira umusaruro w’ingufu n’ubuzima muri rusange, Deazaflavin ashobora kuba amahitamo akwiye, cyane cyane kubafite inenge zizwi cyangwa inzitizi z’imirire zishobora kugira ingaruka kuri vitamine B2. Ku rundi ruhande, abantu bashishikajwe n’inyungu zishobora kurwanya gusaza no guteza imbere ubuzima bw’akagari barashobora kubona NMN ihitamo rikomeye, bitewe n’uruhare rwayo mu kongera urwego rwa NAD + n’umubano wacyo kuramba.
Ibyiza bya 5-deazaflavin hejuru ya NMN
5-Ifu ya Deazaflavin na NMN nibintu byingenzi bibanziriza NAD + kandi bigira uruhare runini muri metabolism selile. Ariko, ugereranije na NMN, 5-deazaflavin ifite ibyiza bikurikira:
1. Guhagarara: 5-deazaflavin wasangaga ihagaze neza kuruta NMN. Ibi bivuze ko ikomeza gukora neza mugihe kirekire, bigatuma iba amahitamo yizewe kubashaka kuyinjiza mubuzima bwabo bwa buri munsi. Guhagarara kwa 5-deazaflavin nabyo byoroha kubika no gutwara, bikayiha inyungu kurenza NMN muburyo bworoshye.
2. Kuboneka: Ugereranije na NMN, 5-deazaflavin yerekanwe ko ifite bioavailable yo hejuru. Ibi bivuze ko igice kinini cya 5-deazaflavin cyinjizwa numubiri, bikavamo ingaruka zigaragara. Hamwe na bioavailable nini, abantu barashobora kubona inyungu za 5-deazaflavin byihuse kandi kuri dosiye iri munsi ya NMN.
3. Redox ishobora: 5-deazaflavin ifite ubushobozi bubi bwa redox kurenza NMN, ituma ishobora kugira uruhare runini muburyo bwa biohimiki.
4. Kwuzuzanya: 5-deazaflavin yunganira izindi coenzymes, nka flavin na nicotinamide, bigatuma metabolism selile yuzuza kandi ikora neza.
5. Imiterere ya Photocatalytic: 5-deazaflavin yerekanwe ko ifite imiterere ya fotokatike kandi irashobora kuba ishobora gukoreshwa mubikorwa bitandukanye.
6.5-Deazaflavin yerekanwe gukora sirtuins, itsinda rya poroteyine zigira uruhare runini mugutunganya ubuzima bwimikorere nubuzima. Mugukoresha sirtuins, 5-deazaflavin irashobora gufasha guteza imbere gusana selile no kuzamura ubuzima muri rusange kurwego rwakagari. Ku rundi ruhande, NMN, ikora cyane cyane mu kongera urwego rwa NAD +, molekile igira uruhare mu ngirabuzimafatizo zitandukanye ariko ntabwo ikora Sirtuins mu buryo butaziguye.
Muri rusange, ifu ya 5-deazaflavin yagiye ihinduka buhoro buhoro kuri NMN kandi ifite ubushobozi bwagutse. Bitandukanye na NMN, ikora mu buryo butaziguye nka coenzyme idahinduwe kuri NAD + .Uyu mutungo udasanzwe utuma ukora neza kurusha NMN, hamwe na raporo zivuga ko ifu ya 5-deazaflavin ifite imbaraga inshuro 40 kugeza 100 kurusha NMN. Kubwibyo, bifatwa nkicyizere kizaza gisimbura NMN.
1. Shigikira umusaruro w'ingufu
Imwe mu nyungu zingenzi zinyongera za deazaflavin ninshingano zabo mugushigikira umusaruro wingufu mumubiri. Deazaflavin afite uruhare runini mu gukora ATP, ifaranga ry’ibanze ry’ingirabuzimafatizo. Mu kongera umusaruro wa ATP, inyongera ya deazaflavin irashobora gufasha kongera urwego rwingufu muri rusange no kurwanya ibyiyumvo byumunaniro nubunebwe.
2. Imiti igabanya ubukana
Antioxydants nibintu bifasha gutesha agaciro radicals yangiza mumubiri igira uruhare mubusaza n'indwara. Mugukora nka antioxydeant, inyongera ya deazaflavin irashobora gufasha kurinda umubiri guhangayika no kugabanya ibyago byindwara zidakira nkindwara z'umutima na diyabete.
3. Gushyigikira ubuzima bwa sisitemu yubuzima.
Deazaflavin afite uruhare runini mukubyara neurotransmitter, ubutumwa bwimiti ituma ingirabuzimafatizo zishyikirana. Mugushyigikira umusaruro wa neurotransmitter, inyongera ya deazaflavin irashobora gufasha kunoza imikorere yubwenge, imyumvire, nubuzima bwo mumutwe muri rusange.
4. Gushyigikira ubuzima bwumutima.
Deazaflavin yerekanwe gushyigikira amaraso meza kandi birashobora gufasha kugabanya ibyago byumuvuduko ukabije wamaraso nindwara zifata umutima. Mugutezimbere amaraso meza, inyongera ya Deazaflavin irashobora kandi gufasha kunoza imikorere yimikino no gushyigikira kwihangana kumubiri.
5. Shigikira imikorere yubudahangarwa
Ubushakashatsi bwerekana ko deazaflavin ishobora gufasha kugenzura imikorere yumubiri kandi ishobora gufasha gushyigikira ubudahangarwa bw'umubiri. Mugushyigikira imikorere yubudahangarwa, inyongera ya deazaflavin irashobora gufasha kugabanya ibyago byo kwandura no gushyigikira ubuzima muri rusange.
6. Kurwanya gusaza
Ubushakashatsi bwerekanye ko 5-deazaflavin ikora inshuro 100 kurusha NMN kandi ishobora gufasha ADN gusana no kurwanya gusaza.
Kubona inyongera ya deazaflavin ningirakamaro kugirango umenye neza ibicuruzwa byiza kandi byiza.
Icyambere, ni ngombwa gusuzuma inkomoko yinyongera ya deazaflavin. Shakisha isosiyete izwi ikoresha ibikoresho byujuje ubuziranenge kandi ikorera mu mucyo kubyerekeye amasoko yayo n'ibikorwa byayo. Soma ibisobanuro byabakiriya hanyuma ukore ubushakashatsi kuri sosiyete kugirango umenye neza ko bafite izina ryiza muruganda. Byongeye kandi, nibyiza guhitamo inyongera zageragejwe nundi muntu wageragejwe kubwera nimbaraga.
Mugihe uhisemo inyongera ya deazaflavin, ni ngombwa nanone gusuzuma imiterere yinyongera. Abantu bamwe bashobora guhitamo capsules cyangwa ibinini, mugihe abandi bashobora guhitamo ifu yifu. Mugihe uhitamo ifishi yinyongera, tekereza kubyo ukunda hamwe nubuzima bwawe. Wibuke ko uburyo butandukanye bwinyongera bushobora no kugira ibipimo bitandukanye byo kwinjiza hamwe na bioavailability.
Ikindi kintu cyingenzi ugomba gusuzuma muguhitamo inyongera ya deazaflavin ni dosiye. Igipimo gikwiye kirashobora gutandukana ukurikije ibintu nkimyaka, uburemere, nubuzima muri rusange. Nibyiza kugisha inama inzobere mubuzima cyangwa inzobere mu mirire kugirango umenye dosiye ikwiye kubyo ukeneye kugiti cyawe. Irinde gufata inyongeramusaruro nyinshi cyane kuko zidakenewe kandi zishobora gutera ingaruka mbi.
Usibye ibipimo, ni ngombwa no gushakisha inyongera ya deazaflavin itarimo inyongeramusaruro cyangwa ibyuzuye bitari ngombwa. Inyongera nyinshi kumasoko zirimo amabara yubukorikori, imiti igabanya ubukana, na allergène ishobora kwangiza ubuzima bwawe. Shakisha inyongera zifite isuku, zera, kandi zifite ibintu bike byongeweho.
Suzhou Myland Pharm & Nutrition Inc.Yatangiye gukora ubucuruzi bwongera imirire kuva mu 1992. Nisosiyete ya mbere mu Bushinwa yateje imbere kandi igacuruza imbuto zinzabibu.
Hamwe nuburambe bwimyaka 30 kandi itwarwa nubuhanga buhanitse hamwe ningamba zinoze cyane R&D, isosiyete yateje imbere ibicuruzwa bitandukanye byapiganwa kandi ihinduka ubumenyi bwa siyanse yubuzima bushya, synthesis gakondo hamwe na serivise zikora inganda.
Byongeye kandi, isosiyete kandi ni uruganda rwanditswe na FDA, rwemeza ubuzima bwabantu bafite ireme rihamye kandi ryiterambere rirambye. Isosiyete R&D umutungo n'ibikoresho byo kubyaza umusaruro nibikoresho byisesengura nibigezweho kandi byinshi, kandi birashobora gukora imiti kuri miligarama kugeza kuri toni yubahiriza ibipimo bya ISO 9001 hamwe nuburyo bwo gukora GMP.
Ikibazo: Inyongera ya deazaflavin niyihe kandi nigute ishobora kugirira akamaro intego zubuzima bwanjye?
Igisubizo: Deazaflavin nuruvange rushyigikira imirimo itandukanye ya metabolike mumubiri, harimo kubyara ingufu nubuzima bwimikorere. Irashobora gushyigikira imibereho myiza muri rusange kandi igafasha intego zubuzima zihariye nko kuzamura ingufu zingirakamaro hamwe na antioxydeant.
Ikibazo: Nigute nahitamo neza inyongera ya deazaflavin kubyo nkeneye?
Igisubizo: Mugihe uhisemo inyongera ya deazaflavin, ni ngombwa gusuzuma ibintu nkubwiza, ubuziranenge, nimbaraga. Shakisha ikirango kizwi gikoresha ibikoresho byujuje ubuziranenge kandi gifite ibizamini byabandi kugirango umenye imbaraga nubuziranenge. Byongeye kandi, tekereza ku ntego zawe zihariye z'ubuzima hanyuma ushakishe inyongera yashyizweho kugirango ishyigikire izo ntego.
Ikibazo: Bifata igihe kingana iki kugirango ubone ibisubizo bivuye mu gufata inyongera ya deazaflavin?
Igisubizo: Igihe bifata kugirango ubone ibisubizo bivuye mu gufata inyongera ya deazaflavin irashobora gutandukana bitewe nibintu bitandukanye nkubuzima rusange, imirire, nubuzima. Abantu bamwe bashobora kubona iterambere ryurwego rwingufu hamwe nubuzima bwiza muri rusange byihuse, mugihe abandi bashobora gufata igihe kirekire kugirango babone inyungu zuzuye. Ni ngombwa guhuza no gufata inyongera nkuko byateganijwe no kuyiha umwanya wo gukora.
Inshingano: Iyi ngingo ni iyamakuru rusange gusa kandi ntigomba gusobanurwa nkinama zose zubuvuzi. Amwe muma poste yamakuru aturuka kuri enterineti kandi ntabwo ari umwuga. Uru rubuga rufite inshingano zo gutondeka, gutunganya no guhindura ingingo. Intego yo gutanga amakuru menshi ntabwo bivuze ko wemera ibitekerezo byayo cyangwa kwemeza ukuri kwibirimo. Buri gihe ujye ubaza inzobere mu buzima mbere yo gukoresha inyongeramusaruro cyangwa guhindura ibintu byubuzima bwawe.
Igihe cyo kohereza: Mutarama-17-2024
