N-acetyl-L-cysteine ethyl ester (NACET) nuburyo bwahinduwe bwa sisitemu ya amino acide kandi ifite antioxydants ikomeye, hepatoprotective, neuroprotective na anti-inflammatory. Ubushobozi bwayo bwo kongera umusaruro wa glutathione, kurinda umwijima, kugenzura imiyoboro ya neurotransmitter no kugabanya gucana bituma iba urugingo rutanga ubuzima bwiza nubuvuzi. Ku rundi ruhande, NACET, ni Ethyl ester ikomoka kuri NAC, itekereza ko yongerera bioavailability hamwe nubushobozi rusange bwa NAC nkukuzamura ubwenge. Muri rusange N-acetyl-L-cysteine ethyl ester yerekana amasezerano akomeye mugutezimbere ubuzima rusange no gukemura ibibazo bitandukanye byubuzima.
N-Acetyl-L-cysteine Ethyl ester, bakunze kwita NACET cyangwa N-acetylcysteine ethyl ester, ni uburyo bwahinduwe bwa aside amine L-cysteine. Bikomoka kuri N-acetylcysteine (NAC) wongeyeho itsinda rya Ethyl ester. L-cysteine iboneka mubisanzwe mubiribwa nk'amagi, inkoko, n'ibikomoka ku mata. NACET izwiho kurwanya antioxydants ikomeye kandi ikoreshwa nk'inyongera y'ibiryo kugirango ifashe ubuzima rusange n'imibereho myiza.
NACET izwi cyane kubushobozi bwayo bwo kongera glutathione mumubiri. Glutathione ni antioxydants ikomeye na molekile ikomeye mubikorwa bitandukanye bya selile. Ifasha gutesha agaciro radicals yubusa kandi ikingira selile zacu guhagarika umutima. Mu kongera glutathione, NACET ishimangira neza sisitemu yo kwirinda antioxydeant yumubiri.
NACET yongerera glutathione urwego, ishyigikira ubuzima bwumwijima, kandi yerekanye ubushobozi bwo kuzamura imikorere yubwenge. Hamwe na bioavailable yabyo, NACET itanga amahitamo meza kubantu bashaka gushyigikira ubuzima rusange n'imibereho myiza.
Guhangayikishwa na Oxidative bibaho mugihe habaye ubusumbane hagati ya radicals yubusa na antioxydants mumubiri. Radicals yubusa ni molekile ikora cyane ishobora kwangiza selile kandi ikagira uruhare mu iterambere ryindwara zitandukanye, zirimo indwara z'umutima n'indwara zifata ubwonko. NACET ifasha kurinda umubiri guhangayika.
Glutathione ni imwe muri antioxydants ikomeye cyane isanzwe ikorwa numubiri. Agira uruhare runini mubikorwa byo kwangiza no gukora sisitemu yumubiri. NACET iteza imbere ubuzima rusange nubuzima bwiza mukongera glutathione no kongera umusaruro wa glutathione kugirango ifashe umubiri kurandura uburozi nibintu byangiza neza.
NACET irashobora gufasha kugenzura urwego rwa neurotransmitter mu bwonko, nka dopamine na glutamate, bigira uruhare runini mugutunganya imiterere no kwizizirwa.
1. Ibintu bikomeye birwanya antioxydeant
NACET ifite ubushobozi bukomeye bwa antioxydeant, kandi imiterere ya antioxydeant ituma iba inyongera nziza kubantu bashaka gukumira ibyangizwa na selile biterwa na stress ya okiside. Muri byo, antioxydants itesha agaciro radicals yangiza mu mibiri yacu, ikarinda selile zacu kwangirika no kugabanya ibyago byindwara zidakira. Mu kurwanya impagarara za okiside, NACET irashobora gufasha guteza imbere gusaza neza, gushyigikira ubuzima bwumutima, no gufasha gushimangira ubudahangarwa bw'umubiri.
2. Ubuzima bwo mu mutwe
Uruhare rwa NACET mubuzima bwo mumutwe rugenda rwitabwaho. Ubushakashatsi bwerekana ko uru ruganda rushobora kugira imiti igabanya ubukana ishobora kugira ingaruka nziza ku buzima bwubwonko. Byongeye kandi, mugutezimbere synthesis ya glutathione, antioxydeant ikomeye, NACET ifasha kugabanya kwangirika kwimitsi kandi irashobora gufasha kunoza imikorere yubwenge. Ubushakashatsi bumwe bwerekana ko NACET ishobora gufasha kuvura indwara ziterwa no kwiheba no guhangayika.
3. Inkunga yumwijima no kwangiza
Umwijima wacu ufite inshingano zo kwangiza ibintu byangiza umubiri. NACET yerekana amasezerano yo guteza imbere ubuzima bwumwijima mugushyigikira uburyo bwo kwangiza no kugabanya imbaraga za okiside mu mwijima. Mugutezimbere umusaruro wa glutathione, NACET ifasha kurandura uburozi, bushobora kurinda umwijima kwangirika no gushyigikira imikorere yabwo muri rusange.
4. Kunoza imikorere yubwenge
Ubushakashatsi bwinshi bwakoze ubushakashatsi ku ngaruka za NACET ku mikorere yubwenge, harimo kwibuka, kwitondera, n'imikorere nyobozi. Ikigeragezo cyateguwe cyakozwe nitsinda ryabashakashatsi ryerekanye ko inyongera ya NACET yazamuye imikorere yimikorere nubushobozi bwo kwibuka mubantu bakuze bazima.
Byizerwa ko ingaruka nziza za NACET kumikorere yubwenge zishobora guterwa nubushobozi bwayo bwo kugenzura urugero rwa glutamate mubwonko. Glutamate ningirakamaro ya neurotransmitter igira uruhare mukwiga no kwibuka. Mugutegeka urwego glutamate, NACET itezimbere itumanaho hagati yubwonko, bityo igateza imbere imikorere yubwenge.
Byongeye kandi, ubushakashatsi bwerekana ko NACET ishobora kuba ifite imitekerereze ya neuroprotective ishobora gufasha kunoza imikorere yubwenge. Yakozweho ubushakashatsi ku bushobozi ifite mu kuvura indwara zifata ubwonko nka Alzheimer's na Parkinson.
1. Inkomoko y'ibiryo
Mugihe amasoko y'ibiribwa asanzwe adafite urugero runini rwa N-acetyl-L-cysteine ethyl ester, irimo sisitemu, ihinduka NACET mumubiri. Ibiribwa bikungahaye kuri sisitemu birimo inkoko, amagi, ibikomoka ku mata, ibishyimbo, tungurusumu, igitunguru, broccoli na Bruxelles. Kwinjiza ibyo biryo mumirire yawe birashobora kugufasha gutanga isoko ihagije ya sisitemu, ifasha kubyara NACET mumubiri.
2. Ibiryo byongera ibiryo
Inyongera nubundi buryo bwizewe bwo kubona N-acetyl-L-cysteine ethyl ester. Urashobora kubona inyongera ya NACET muburyo bwinshi, harimo capsules, ibinini, cyangwa ifu. Ni ngombwa kumenya ko mbere yo kongeramo ibintu bishya mubikorwa byawe bya buri munsi, birasabwa kugisha inama inzobere mu by'ubuzima kugira ngo urebe ko bihuye n'ubuzima bwawe bwa none.
Wige ibya NAC
N-Acetyl Cysteine, bakunze kwita NAC, ni antioxydants ikomeye kandi ibanziriza glutathione, antioxydants y'ibanze y'umubiri. Nubushobozi bwayo bukomeye bwo gusibanganya radicals yubusa no gushyigikira umwijima, NAC irazwi cyane kubuzima bwiza. Kuva ku buzima bw'ubuhumekero kugeza kwangiza umwijima, NAC yahindutse inzira yiyongera kubantu bagamije kuzamura ubuzima bwabo muri rusange.
Kuzamuka kwa NAC ethyl ester
NAC ethyl ester ni inkomoko ya NAC kandi irimo gutezwa imbere nkibishobora kuzamurwa uhereye kubayibanjirije. Inzira ya esterification ihindura imiterere ya molekulari ya NAC, ikongerera bioavailability no guteza imbere ingirabuzimafatizo.
Bioavailability and Absorption
Ikintu cyingenzi mugereranya NAC na NAC ethyl ester ni bioavailable yabo nigipimo cyayo. NAC irashobora guhura ningorane zo kurenga inzitizi z’ibinyabuzima no kugera ku rwego rwo kuvura kugira ngo isibe neza uburozi no kurinda selile. Mugereranije, NAC ethyl ester irashobora kuboneka cyane kandi irashobora kwinjizwa neza no gukoreshwa mumubiri. Ubu buryo bunoze bwo gutanga bushobora kuganisha ku nyungu nyinshi mugihe ugamije ibibazo byubuzima byihariye.
Glutathione Kugarura neza
Intego nyamukuru yo kuzuza NAC ni uguteza imbere umusaruro wa glutathione mumubiri. Glutathione igira uruhare runini mukurinda selile kurwanya okiside kandi ishyigikira imikorere itandukanye yumubiri. Nubwo NAC izwiho ubushobozi bwo kongera glutathione, ubushakashatsi bwerekana ko estyl estyl ester ishobora kurenga NAC muriki kibazo. Kwiyongera kwinshi kwa NAC Ethyl ester irashobora gufasha kugarura urwego rwa glutathione neza, bitanga uburinzi bwingirabuzimafatizo.
Ikibazo: NACET irashobora kunoza imikorere yubwenge?
Igisubizo: Ubushakashatsi bumwe bwerekana ko inyongera ya NACET ishobora kugira ingaruka nziza mumikorere yubwenge. Yakozweho ubushakashatsi nk'indwara ya Alzheimer, indwara ya Parkinson, na schizofrenia, yerekana iterambere rishobora kuba mu kwibuka, kwitabwaho, no mu mirimo nyobozi. Nyamara, ubushakashatsi burakenewe kugirango hamenyekane imikorere yabwo na dosiye nziza yo kongera ubwenge.
Ikibazo: Ni he nshobora kugura NACET?
Igisubizo: NACET iraboneka cyane nkinyongera-ya-farumasi muri farumasi, mububiko bwibiryo byubuzima, no kubicuruza kumurongo. Ni ngombwa kugura ahantu hizewe kugirango hamenyekane ubuziranenge n'umutekano.
Inshingano: Iyi ngingo ni iyamakuru rusange gusa kandi ntigomba gusobanurwa nkinama zose zubuvuzi. Amwe muma poste yamakuru aturuka kuri enterineti kandi ntabwo ari umwuga. Uru rubuga rufite inshingano zo gutondeka, gutunganya no guhindura ingingo. Intego yo gutanga amakuru menshi ntabwo bivuze ko wemera ibitekerezo byayo cyangwa kwemeza ukuri kwibirimo. Buri gihe ujye ubaza inzobere mu buzima mbere yo gukoresha inyongeramusaruro cyangwa guhindura ibintu byubuzima bwawe.
Igihe cyo kohereza: Nzeri-27-2023
