Spermidine Irwanya Gusaza-Ibyo Ukeneye Kumenya

Spermidine ni ibisanzwe bisanzwe bya polyamine biboneka mu ngirabuzimafatizo zose. Ifite uruhare runini mumikorere ya selile, harimo gukura kwakagari, gukwirakwizwa, no gutandukana. Spermidine ikomatanyirizwa mu mubiri ivuye muyindi polyamine yitwa putrescine, igira uruhare mu binyabuzima bitandukanye, birimo ADN itajegajega, imiterere ya gene, na metabolism selile.

Ni izihe nyungu zaspermidine?

①Spermidine irashobora kwigana intungamubiri za caloric kandi igatanga inyungu zo kwiyiriza ubusa;

②Spermidine irashobora kongera autophagy, ikagira uruhare muri "disoxification" ya selile, kandi igakora imiyoboro myinshi irwanya gusaza - kubuza mTOR no gukora AMPK, bityo bikarwanya gusaza;

③Kwongera gufata intanga ngabo birashobora gufasha kurwanya kanseri, diyabete, indwara z'umutima n'imitsi ndetse na neurodegeneration;

StudiesUbushakashatsi bumwe na bumwe bwerekana ko spermidine ishobora gutera umusatsi.

Sub-gusohora & autophagy

Ibyiza byubuzima no kuramba byo kubuza kalori kubwo kwiyiriza ubusa birazwi, ariko kubera ko abantu bake cyane bashoboye kubahiriza igisibo gihoraho, inyungu zabo zose zubuzima zirashobora gutakara.

Cyangwa kwigana kaloriki yigana nka spermidine irashobora gukoreshwa mukwigana leta yisonzesha no kubona inyungu zubuzima zidafite ingaruka mbi ziterwa ninzara igihe kirekire.

Mu kwihutisha autophagy, spermidine irashobora kugira akamaro kanini mubuzima.

Urugero, Autophagy, itekereza gukumira uburibwe no guhagarika umutima, bityo bikagabanya ibyago byindwara ziterwa nimyaka (harimo kanseri, indwara ziterwa na metabolike, indwara z'umutima, n'indwara zifata ubwonko) n'urupfu.

Usibye gukumira indwara ziterwa nimyaka, spermidine irashobora kunoza ibintu byinshi byumubiri byo gusaza, hamwe nikimwe mubimenyetso bigaragara byubusaza bituruka kuminkanyari hamwe nibibara mumaso yacu.

Uruhu ni urugingo runini rwumubiri wumuntu kandi rugizwe nubwoko butandukanye bwingirabuzimafatizo, harimo lipide, keratin, na sebum, zikora nkinzitizi yo kwirinda ibidukikije bikabije.

Ubushakashatsi bwakorewe mu bantu ku miterere y'uruhu rw'umuntu n'imikorere ya barrière bwerekanye ingaruka zo kurwanya gusaza kwa spermidine ku ruhu.

Spermidine ituruka he?

Mu mubiri w'umuntu, hari amasoko 3 y'ingenzi ya spermidine:

TIshushanya n'umubiri w'umuntu ubwawo

Irashobora kuva kuri arginine kugeza kuri ornithine kugeza putrescine kuri spermidine, cyangwa irashobora guhinduka kuva muri spermine

TBiva mu biryo

Omes Amafaranga ava muri synthesis ya flora yo munda

Nigute ushobora kongera urugero rwa spermidine

01. Gutera intangangore za spermidine

Kwinjiza intanga za spermidine birashobora kongera intanga ngabo, kandi arginine na spermine byombi bishobora kugira ingaruka.

Ibiryo bikungahaye kuri Arginine ni imbuto, imbuto n'ibinyamisogwe, na turukiya, mu gihe ibiryo bikungahaye ku ntanga zirimo mikorobe y'ingano, umwijima w'inkoko, imitima y'inkoko, n'amara y'inka.

Komeza methylation nziza

Ikigaragara ni uko kubungabunga methylation nzima ningirakamaro kuri synthesis ya spermidine.

Synthesis ya spermidine isaba uruhare rwa dcSAMe, ikomoka kuri SAMe.

SAMe ni coenzyme yingenzi cyane muri methylation yabantu, kandi urwego rwayo rugira ingaruka kuri methylation cycle.

33. Kubona ibiryo

Birumvikana ko inzira itaziguye ari ukubona spermidine mu biryo. Ibiribwa bikungahaye kuri spermidine ahanini ni ishingiro ryinyamaswa n'ibimera, nka mikorobe y'ingano, ibishyimbo, imbuto, ibisimba n'umwijima w'inyamaswa (birumvikana ko mikorobe y'ingano irimo gluten) ya).

44. Inyongera za spermidine

Mugihe imibiri yacu ishobora kubyara spermidine, iboneka no mubiribwa bimwe na bimwe, bigatuma gufata indyo yingenzi muburyo bwo gukomeza urwego rukwiye. Ibiryo bikungahaye kuri spermidine birimo foromaje ishaje, ibihumyo, ibikomoka kuri soya, ibinyamisogwe, ibinyampeke, n'imbuto n'imboga zimwe. Nyamara, kwibumbira hamwe kwa spermidine muri ibyo biryo birashobora gutandukana, bigatuma abantu benshi bafata inyongera nkuburyo bwo kongera ibyo bafata.

Ni he ushobora kubona spermidine nziza

Muri iki gihe inganda z’ibinyabuzima n’inganda zikora imiti, spermidine (spermidine), nka amine yingenzi ya biogenic, yakunze kwitabwaho cyane kubera uruhare runini mu mikurire y’utugingo, ikwirakwizwa no gusaza. Mu gihe ubushakashatsi ku buzima no kuramba bukomeje, icyifuzo cya spermidine gikomeje kwiyongera. Nyamara, ubwiza bwa spermidine ku isoko ntiburinganiye, kandi nuburyo bwo kubona spermidine yo mu rwego rwo hejuru byabaye intumbero y’abashakashatsi n’amasosiyete benshi.

Spermidine amakuru yibanze

Imiterere yimiti ya spermidine iroroshye, hamwe numero CAS ya 124-20-9. Imikorere myinshi yibinyabuzima mu ngirabuzimafatizo bituma iba molekile ikomeye mu gusaza, autofagy na antioxydeant. Ubushakashatsi bwerekana ko spermidine ishobora guteza imbere autofagy selile, gutinda gusaza, no kunoza ubushobozi bwa antioxydeant ya selile kurwego runaka. Kubwibyo, kubona spermidine-yera cyane ningirakamaro mubushakashatsi bwa siyansi no kuyishyira mu bikorwa.

Ibyiza bya Suzhou Myland

Mu batanga intanga nyinshi, Suzhou Myland yihagararaho kubera ibicuruzwa byiza na serivisi zumwuga. Intanga ngabo yatanzwe naSuzhou MylandifiteCAS numero 124-20-9 hamwe nubuziranenge burenga 98%. Ibicuruzwa bifite isuku nyinshi ntabwo byujuje ubuziranenge mpuzamahanga gusa, ahubwo binakorerwa ibizamini byujuje ubuziranenge kugirango buri cyiciro cyibicuruzwa bishobore gukenera ubushakashatsi bwa siyansi no gukoresha inganda.

1. Ubwishingizi bufite ireme

Suzhou Myland azi ko ubuziranenge bwibicuruzwa aribwo shingiro ryimishinga yo kubaho no kwiteza imbere. Isosiyete ifite ibikoresho bigezweho byo gukora hamwe na sisitemu ihamye yo gucunga neza kugirango spermidine ikore igeragezwa kandi igenzurwe. Yaba amasoko y'ibikoresho fatizo cyangwa buri kintu cyose cyakozwe, Suzhou Myland yihatira kugera ku ntera nziza no kwemeza isuku n’ibicuruzwa byiza.

2. Inkunga yumwuga

Usibye gutanga spermidine yo mu rwego rwo hejuru, Suzhou Myland inaha abakiriya inkunga yubuhanga. Yaba ikoreshwa ryibicuruzwa, imiterere yububiko, cyangwa igishushanyo mbonera kijyanye nubushakashatsi, itsinda rya tekinike ryisosiyete irashobora guha abakiriya ubuyobozi nibisobanuro birambuye. Iyi serivisi yitonze ntabwo itezimbere abakiriya gusa, ahubwo inongerera abakiriya ikizere kubicuruzwa.

3. Igiciro cyo guhatanira

Mu rwego rwo kwemeza ubuziranenge bwibicuruzwa, Suzhou Myland yiyemeje kandi guha abakiriya ibiciro byapiganwa. Muguhindura uburyo bwo gukora no gucunga amasoko, isosiyete irashobora kugabanya neza ibiciro, bityo igasubiza ibiciro byoroheje kubakiriya. Ibi bifasha ibigo byinshi byubushakashatsi nubumenyi kubona spermidine yo mu rwego rwo hejuru ku giciro cyiza kandi igateza imbere ubushakashatsi bujyanye.

Kugura

Niba ushaka spermidine yo mu rwego rwo hejuru,Suzhou Mylandnta gushidikanya ni amahitamo yizewe. Urashobora kubona amakuru menshi ukoresheje urubuga rwemewe rwisosiyete cyangwa ukabaza itsinda ryabacuruzi mu buryo butaziguye. Yaba ari ntoya yubushakashatsi bukenewe cyangwa ninganda nini zinganda, Suzhou Myland irashobora gutanga ibisubizo byoroshye ukurikije ibyo abakiriya bakeneye.