Waba uri munzira nziza kandi ushakisha inyongera kugirango uzamure ubuzima bwumubiri nubwenge? Reba ibirenze 7,8-dihydroxyflavone inyongera. 7,8-Dihydroxyflavone ni flavonoide iboneka mu bimera bimwe na bimwe kandi yakozweho ubushakashatsi ku nyungu zayo ku buzima. Ubushakashatsi bwerekana ko 7,8-dihydroxyflavone ifite neuroprotective, anti-inflammatory, na antioxydeant, bigatuma iba inyongera yubuzima muri rusange. Niba ushaka gufata urugendo rwubuzima bwawe kurwego rukurikira, tekereza kwinjiza 7,8-dihydroxyflavone inyongera mubikorwa byawe bya buri munsi.
Noneho mubyukuri7,8-dihydroxyflavone? 7,8-DHF ni flavonoide iboneka mu bimera n'imboga zimwe. Yavumbuwe mugihe cyo gushakisha molekile yigana imikorere yikintu gikomoka mu bwonko gikomoka ku bwonko (BDNF), molekile ntoya ikora reseptor yihariye yitwa tropomyosine ifitanye isano na kinase B (TrkB) kubera ko peptide ikora kuri iyi reseptor, yitwa ubwonko- bikomoka kuri neurotrophique (BDNF), ntibishobora gukoreshwa kubera malabsorption n'ubwonko.
7,8-DHF wasangaga yigana imbaraga za BDNF, ikora muburyo busa kuri TrkB. Ibi bivuze ko 7,8-DHF ishobora kubyara ingaruka nkubwonko nka BDNF, kandi ishobora kuba ingirakamaro mubuvuzi bitewe no kuyifata neza hamwe nubushobozi bwo kurenga inzitizi yubwonko bwamaraso.
Bitewe nubushobozi bwayo bwo gukurura reseptor ya TrkB, reseptor ya TrkB igira uruhare runini mugukura no kubaho kwa neurone mubwonko. Iyo reseptor ya TrkB ikora, neuron ikunda gukura no gukingirwa. Iri terambere rikunze kugira ingaruka kuri dendrite ya neuron, igera muri synaps kugirango ivugane na neurone yakurikiyeho, kandi 7,8-DHF yerekanwe guteza imbere imikurire ya dendrite muri synaps, ifasha kugarura inyamaswa Itumanaho hagati ya neuron muburyo bwo kumenya kugabanuka.
Ubushakashatsi bwinshi bwerekana ko 7,8-DHF ishobora kuba ifite ubushobozi bwo kunoza imyigire no kwibuka, kwirinda indwara zifata ubwonko, ndetse no gushyigikira ubuzima nubuzima bwamarangamutima. Ibyavuye mu bushakashatsi byatumye abantu bashishikazwa n’inyongeramusaruro 7,8-dihydroxyflavone nkuburyo busanzwe bwo gushyigikira ubuzima bwubwonko.
Abantu benshi bahindukirira 7,8-dihydroxyflavone yinyongera kugirango bashyigikire imikorere yabo yubwenge, cyane cyane uko basaza cyangwa bahura nibibazo bijyanye no kwibuka no kwibanda. Igitekerezo cyaGukoresha ibinyabuzima bisanzwe kugirango ushyigikire ubuzima bwubwonko birashimishije cyane cyane kubantu bakunda uburyo busanzwe, bwuzuye kubuzima.
Bumwe mu buryo bwibanze bwibikorwa bya 7,8-dihydroxyflavone nubushobozi bwayo bwo gukora tropomyosine reseptor kinase B (TrkB) yerekana inzira. TrkB niyakira kubintu bya neurotrophique yibintu bikomoka mu bwonko bikomoka ku bwonko (BDNF) kandi bigira uruhare runini mu mikurire, kubaho, n'imikorere ya neurone muri sisitemu yo hagati na peripheri. Gukora reseptor ya TrkB na 7,8-dihydroxyflavone biganisha kuri fosifora yumutungo wacyo, bikurura urukurikirane rwibintu byerekana ibimenyetso, amaherezo bigatera ubuzima bwa neuronal kubaho, gukura no gutandukana.
Ubushakashatsi bwerekanye ko 7,8-dihydroxyflavone yerekana ingaruka za neuroprotective mu buryo butandukanye bw’indwara zifata ubwonko, nk'indwara ya Alzheimer n'indwara ya Parkinson. Mugukoresha inzira yerekana inzira ya TrkB, 7,8-dihydroxyflavone yongerera ubuzima bwa neuron, ikabarinda guhagarika umutima no gutwika, kandi igateza imbere gushiraho imiyoboro mishya ya synaptic, ishobora gutinda cyangwa no guhindura ibyo kugabanuka. iterambere ry'indwara.
Usibye ingaruka za neuroprotective, 7,8-dihydroxyflavone byagaragaye ko ifite ingaruka za anxiolytike. Izi ngaruka zitekereza ko zahujwe nubushobozi bwazo bwo kongera ingaruka za BDNF mubwonko, bityo bikazamura plastike ya neuronal no kwihangana mugihe cyo guhangayika no guhungabana. Byongeye kandi, ubushakashatsi bwibanze bwerekanye ko 7,8-dihydroxyflavone ishobora kongera imyigire no kwibuka, bigatuma bishoboka ko ikoreshwa mu kuvura ubumuga bwo mu mutwe bujyanye n’ibibazo nko guta umutwe no gukomeretsa ubwonko.
Ibimenyetso bishya byerekana ko bishobora no kugira ingaruka nziza ku zindi ngingo n'ingingo. Kurugero, 7,8-dihydroxyflavone yerekanwe ko ifite imiti igabanya ubukana, antioxydeant muburyo butandukanye bwimikorere yinyamanswa ninyamaswa, byerekana ko ishobora kuvura indwara zidakira.
Kimwe mu bimera bifite 7-8 dihydroxyflavonoide ni Tridax procumbens, bakunze kwita daisy cyangwa Tridax daisy. Iki gihingwa kavukire mu turere dushyuha kandi gisanzwe gikoreshwa mu buvuzi bwa Ayurvedic kubera imiti myinshi y’imiti. Abashakashatsi basanze Tridax procumbens irimo dihydroxyflavonoide 7 kugeza kuri 8, bikurura inyungu mu gucukumbura inyungu zabyo ku buzima.
Ikindi gihingwa kirimo 7-8 dihydroxyflavone ni igihingwa cya Godmania aesculifolia, kavukire cya Mexico. Iki gihingwa gikoreshwa mubuvuzi gakondo bwa Mexico kugirango kirwanya inflammatory na analgesic. Ubushakashatsi bwerekana ko Godmania aesculifolia irimo 7-8 dihydroxyflavone, yatumye hakorwa ubundi bushakashatsi mubishobora gukoreshwa mu kuvura.
Usibye Tridax procumbens na Godmania aesculifolia, ibindi bimera byinshi bikekwa kuba birimo 7-8 dihydroxyflavonoide, nubwo hakenewe ubushakashatsi bwinshi kugirango hemezwe ko muri ibyo bimera. Harimo fisetin na acacia shrub.
1. Ubushakashatsi bwerekana ko 7,8-DHF ifasha kunoza kwibuka, kwiga, hamwe nibikorwa byubwonko muri rusange. Mugutezimbere gukura kwingirabuzimafatizo nshya no gushimangira isano iri hagati ya neurone zihari, 7,8-dihydroxyflavone inyongera irashobora gufasha mubuzima bwubwonko bwawe nubushobozi bwubwenge.
2.Inkunga Nziza: Usibye inyungu zubwenge, 7,8-dihydroxyflavone inyongera byagaragaye ko igira ingaruka nziza kumyumvire. Ubushakashatsi bwerekana ko 7,8-DHF ishobora gufasha kugenzura imiterere ya neurotransmitter ijyanye nubwonko, nka dopamine na serotonine, bigira uruhare runini mugutunganya imyumvire. Mugushyigikira izo neurotransmitter, 7,8-dihydroxyflavone inyongera zishobora gufasha kunoza imyumvire nubuzima bwamarangamutima muri rusange.
3. Ingaruka za Neuroprotective: 7,8-dihydroxyflavone inyongera nazo wasangaga zifite imiterere ya neuroprotective. Ibi bivuze ko zishobora gufasha kurinda ubwonko na sisitemu sisitemu ibyangiritse biterwa na stress ya okiside, gutwika nibindi bikorwa byangiza. Mugushyigikira ubuzima n'imikorere y'uturemangingo twubwonko, 7,8-dihydroxyflavone inyongera irashobora gufasha kwirinda indwara zifata ubwonko ndetse no kugabanuka kwubwenge.
4. Inkunga ya Antioxydeant: Iyindi nyungu nini yinyongera 7,8-dihydroxyflavone ninyongera ya antioxydeant. Antioxydants ni ibintu bifasha kurinda umubiri kwangirika gukabije, bikaba molekile yangiza ishobora kugira uruhare mu ndwara zitandukanye zidakira no gusaza. Mugukuraho radicals yubusa no kugabanya imbaraga za okiside, 7,8-DHF irashobora gufasha mubuzima rusange nubuzima bwiza.
5.Ingaruka zo kurwanya inflammatory: Gutwika ni inzira karemano ifasha umubiri kurwanya kwandura no gukiza ibyangiritse. Nyamara, gutwika karande bishobora gutera ibibazo bitandukanye byubuzima, harimo indwara z'umutima, diyabete, na kanseri. 7,8-Inyongera ya Dihydroxyflavone byagaragaye ko ifite ingaruka zo kurwanya inflammatory, ifasha kugabanya ibyago byo gutwika indwara zidakira ndetse n’ingaruka ziterwa n’ubuzima.
Kimwe mu bintu byambere ugomba gusuzuma muguhitamo inyongera ya 7.8-dihydroxyflavone nubwiza bwibigize. Shakisha inyongeramusaruro zirimo ubuziranenge, bwiza-7,8-DHF nta byongeweho byuzuzanya cyangwa ibihimbano. Ni ngombwa kandi gusuzuma inkomoko yawe 7,8-DHF - reba inyongera zageragejwe kubwera nimbaraga.
Usibye ubuziranenge bwibigize, ni ngombwa no gusuzuma igipimo nuburyo bwinyongera. 7,8-Dihydroxyflavone iraboneka muburyo bwa capsule na poro, kandi dosiye irashobora gutandukana mubicuruzwa. Nyamuneka suzuma ibyo ukunda kandi ukeneye mugihe uhisemo ifishi na dosiye nziza kuri wewe. Birashobora kandi kuba byiza kugisha inama inzobere mubuzima kugirango umenye dosiye ijyanye nibyo ukeneye kugiti cyawe.
Ikindi kintu cyingenzi ugomba gusuzuma muguhitamo 7,8-dihydroxyflavone inyongera ni izina ryuwabikoze. Shakisha inyongera zakozwe nisosiyete izwi ifite amateka yo gukora ibicuruzwa byiza-byiza, byizewe. Reba ibyemezo nkibikorwa byiza byo gukora (GMP) hamwe nugupima kwabandi bantu kugirango urebe ko inyongera zawe zujuje ubuziranenge n’umutekano.
Nibyiza kandi gusoma ibisobanuro nubuhamya bwabandi bakoresha kugirango ubone igitekerezo cyingirakamaro nubwiza bwinyongera. Shakisha ibitekerezo kubantu bakoresheje iki gicuruzwa mugushigikira ubwenge hamwe nubuzima bwubwonko muri rusange kugirango wumve neza uburyo iyi nyongera igukorera.
Hanyuma, tekereza ikiguzi nagaciro kinyongera. Mugihe ari ngombwa guhitamo ibicuruzwa byujuje ubuziranenge, ni ngombwa nanone gusuzuma igiciro nagaciro kinyongera. Gereranya ibiciro hanyuma urebe ikiguzi kuri buri serivisi kugirango umenye neza ko amafaranga yawe afite agaciro.
Suzhou Myland Pharm & Nutrition Inc. Yatangiye gukora ubucuruzi bwongera imirire kuva mu 1992. Nisosiyete ya mbere mu Bushinwa yateje imbere kandi igacuruza imbuto zinzabibu.
Hamwe nuburambe bwimyaka 30 kandi itwarwa nubuhanga buhanitse hamwe ningamba zinoze cyane R&D, isosiyete yateje imbere ibicuruzwa bitandukanye byapiganwa kandi ihinduka ubumenyi bwa siyanse yubuzima bushya, synthesis gakondo hamwe na serivise zikora inganda.
Byongeye kandi, isosiyete kandi ni uruganda rwanditswe na FDA, rwemeza ubuzima bwabantu bafite ireme rihamye kandi ryiterambere rirambye. Isosiyete R&D umutungo n'ibikoresho byo kubyaza umusaruro nibikoresho byisesengura nibigezweho kandi byinshi, kandi birashobora gukora imiti kuri miligarama kugeza kuri toni yubahiriza ibipimo bya ISO 9001 hamwe nuburyo bwo gukora GMP.
Ikibazo: 7,8-Dihydroxyflavone ni iki?
Igisubizo: 7,8-Dihydroxyflavone ni flavonoide isanzwe ibaho yakozweho ubushakashatsi kubwinyungu zishobora kuba nziza, harimo n'ingaruka zayo mumikorere yubwenge no kumererwa neza muri rusange.
Ikibazo: Nigute inyongera 7,8-Dihydroxyflavone ikora?
Igisubizo: 7,8-Dihydroxyflavone inyongera zizera ko zikora mugushigikira imikorere ya proteine yingenzi mubwonko bwitwa TrkB, igira uruhare mukuzamuka no kubaho kwa neuron. Iyi nkunga irashobora kugira uruhare mu kunoza imikorere yubwenge no kumererwa neza mumutwe.
Ikibazo: Ni izihe nyungu zishobora guterwa no gufata 7,8-Dihydroxyflavone?
Igisubizo: Inyungu zimwe zishobora gufata 7,8-Dihydroxyflavone yinyongera zishobora kuba zirimo kwibuka cyane hamwe nibikorwa byubwenge, gushyigikira ubuzima bwubwonko muri rusange, hamwe ningaruka zishobora gutera imbaraga.
Ikibazo: Nigute inyongera 7,8-Dihydroxyflavone?
Igisubizo: Igipimo gikwiye cyinyongera 7,8-Dihydroxyflavone irashobora gutandukana bitewe nimpamvu zitandukanye, nibyiza rero gukurikiza urugero rwasabwe kurutonde rwibicuruzwa cyangwa kugisha inama inzobere mubuzima kugirango ikuyobore.
Inshingano: Iyi ngingo ni iyamakuru rusange gusa kandi ntigomba gusobanurwa nkinama zose zubuvuzi. Amwe muma poste yamakuru aturuka kuri enterineti kandi ntabwo ari umwuga. Uru rubuga rufite inshingano zo gutondeka, gutunganya no guhindura ingingo. Intego yo gutanga amakuru menshi ntabwo bivuze ko wemera ibitekerezo byayo cyangwa kwemeza ukuri kwibirimo. Buri gihe ujye ubaza inzobere mu buzima mbere yo gukoresha inyongeramusaruro cyangwa guhindura ibintu byubuzima bwawe.
Igihe cyo kohereza: Gashyantare-20-2024
