Squalene ni iki kandi ni ukubera iki ukwiye kubyitaho?

Mugihe abantu barushijeho guhangayikishwa nubuzima bwabo, Squalene iragenda ikundwa cyane nubushuhe buhebuje ndetse na antioxydeant. Nkibintu bisanzwe bibaho, Squalene ikoreshwa cyane mubicuruzwa byita kuruhu, kwisiga hamwe ninyongera zimirire. Mugihe abaguzi bakeneye ibintu bisanzwe bikomeje kwiyongera, niko no gukenera ifu nziza ya squalene nziza ku isoko.

Squalene (CAS: 111-02-4) ni amavuta atagira ibara. Nibintu byose byitwa triterpene byuzuye hamwe na isoprene kandi ni ikintu cyingenzi muburyo bwa cholesterol metabolism yumuntu. Urufunguzo rwibanze, terpenoide ikunze kuboneka mubitunga umubiri no kwisiga. Squalene ikekwa ko ifite inyungu nyinshi kumubiri wumuntu, harimo kugabanya lipide yamaraso, antioxydeant, anti-inflammatory ningaruka zongera ubudahangarwa. Squalene irashobora kugira uruhare muri metabolism nkibibanziriza synthesis ya steroid, kandi ikagira uruhare runini muburyo bwo guhuza inzira ya β-karotene, coenzyme Q10, vitamine D, vitamine E na vitamine K1.

Squalene iboneka cyane mu nyamaswa, ibimera na mikorobe. Ihinduranya muri endoplasmic reticulum ikabikwa muri vicles cyangwa ikoherezwa muri selile ikoresheje imitsi. Kubera ibikorwa bikomeye byibinyabuzima, bikoreshwa cyane mubiribwa no kwisiga. Inganda. Squalene iboneka mu biribwa byinshi, muri byo harimo amavuta y’umwijima y’umwijima arimo urugero rwo hejuru, kandi amavuta y’ibimera nkamavuta ya elayo hamwe n amavuta yumuceri wumuceri nabyo birimo urugero rwa squalene.

Squalene ifite ingaruka nyinshi za bioactive, harimo kunoza kwihanganira hypoxia, kubuza imikurire ya mikorobe, antibacterial na anti-inflammatory, no kugenzura metabolism ya cholesterol. Byongeye kandi, ifite ubushobozi bwo kuzimya ogisijeni imwe rukumbi, irinda neza uruhu kwirinda lipide peroxidisation no kurinda selile kwangirika kwa ADN. Iyi ngingo kandi yerekana ibikorwa bitandukanye byingenzi byumubiri nko kwirinda indwara zifata umutima ndetse no kongera ubudahangarwa bwabantu.

Intangiriro kumikorere ya squalene

1. Igikorwa cyo kurwanya antioxydeant

Squalene irashobora gukumira neza reaction ya radicals yubusa mumubiri wumuntu kandi ikagira uruhare rwa antioxydeant. Molekile ya squalene igizwe na 6 idahujwe hamwe idahuza inshuro ebyiri kandi ifite antioxydeant ikomeye.

2. Ingaruka za Antibacterial na anti-inflammatory

Squalene ifite antibacterial, anti-inflammatory na bactericidal kandi irashobora gukoreshwa mu kwandura indwara zo mu myanya y'ubuhumekero n'indwara z'uruhu ziterwa na bagiteri, ndetse no gutwikwa, ibisebe by'uruhu n'indwara ziterwa na aphite. Ubushakashatsi bwerekana ko squalene ishobora kwihutisha inzira yo gukira ibikomere no gukata. Kurwanya anti-inflammatory na antioxydeant bifasha mugukiza byihuse, bigatuma byongerwaho agaciro mubikoresho byose byubufasha bwambere

3. Ubuntu bwa radical scavenger, kongera ubudahangarwa

Squalene ifite imbaraga zikomeye zo gukata radical kandi ifite uruhare runini mugutezimbere metabolism yabantu. Mugukoresha metabolisme, squalene ifasha kunoza imitekerereze yumubiri no gukoresha neza intungamubiri, bityo bigateza imbere ubuzima. Nkibintu byongera ibiryo bikora, squalene ikoreshwa mubicuruzwa bitandukanye byubuzima, nkibiryo byongera imirire, ibiryo byubuzima, nibinyobwa bikora. Ubushakashatsi nogukoresha squalene nabyo bigenda byiyongera, biha abantu amahirwe menshi yo kubona inyungu zubuzima binyuze mubiryo.

4. Kuvomera no kurwanya antioxydeant

Squalene ifite inyungu nyinshi zubuzima bwuruhu, harimo kurinda imirasire ya UV na antioxydeant. Itezimbere uruhu, igabanya imyenge n’iminkanyari, kandi igahindura uruhu idateye uburakari. Ubushakashatsi bwakorewe ku bagore barengeje imyaka 50 bwerekanye ko gufata squalene bishobora kugabanya cyane iminkanyari zo mu maso kandi bigatera uburibwe bwo mu maso hamwe na pigmentation. Byongeye kandi, squalene irashobora kongera ibikorwa bya enzyme ya antioxydeant yuruhu, kandi ingaruka ni nziza cyane kuruta vitamine E. Bitewe ningaruka nziza za emollient, ibirango bimwe na bimwe bizwi cyane byo kwisiga byakoresheje mubicuruzwa byuruhu no kumisatsi nka hydrated serumu no kwita kuruhu. amavuta.

3. Gusaba inganda za squalene

1). Squalene nibicuruzwa byayo bya hydrogène irazwi cyane mubikorwa byinshi byo kwisiga. Squalene ifite inyungu nyinshi zubuzima bwuruhu, harimo kurinda imirasire ya UV na antioxydeant. Itezimbere uruhu, igabanya imyenge n’iminkanyari, kandi igahindura uruhu idateye uburakari.

2). Nka mavuta karemano, squalene ikoreshwa cyane nkumutwaro wa biocompatible ibiyobyabwenge kugirango urekure ibiyobyabwenge. Imiti ya Emulsion irimo squalene irashobora kongera igice cyubuzima bwibiyobyabwenge.

3). Squalene yerekanye ubushobozi bwinshi bwo gukoresha mubushakashatsi bwubuvuzi: muri selile HepG2, irashakisha uburyo bwo kugabanya cholesterol mukurinda ikwirakwizwa rya selile no kongera imvugo ya LDLR; icya kabiri, ubushakashatsi bwa docking bwerekana ko squalene ishobora kugira uruhare mukuvura kanseri y'uruhu kugira uruhare; amaherezo, mugukusanyirizwa muri PLGA NPs, gufata neza selile mumavuta ya elayo biratera imbere, kandi bifite ubushobozi bwo kubungabunga ubuzima bwimikorere no kurwanya stress ya okiside.

4). Nkibintu byongera ibiryo bikora, squalene yakunze abantu benshi kandi yizwe cyane kubera uruhare rwayo mukurinda indwara zifata umutima, kanseri nizindi ndwara.

Kugura Squalene?

Ibintu by'ingenzi muguhitamo utanga isoko

1. Ubwiza bwibicuruzwa

Iyo uhisemo utanga isoko, ikintu cya mbere ugomba gusuzuma ni ubwiza bwibicuruzwa. Ifu yuzuye ya squalene ifata ibikorwa byibinyabuzima no gukora neza. Ifu ya Squalene itangwa na Suzhou Myland yakorewe ibizamini byujuje ubuziranenge kugira ngo buri cyiciro cyibicuruzwa cyujuje ubuziranenge mpuzamahanga kandi cyemeza ubuziranenge.

2. Ubushobozi bwo gukora

Ubushobozi bwumusaruro bugira ingaruka muburyo butaziguye no kugemura. Suzhou Myland ifite ibikoresho byubuhanga n’ikoranabuhanga bigezweho bishobora guhuza ibikenerwa n’umusaruro rusange, byemeza ko abakiriya bashobora kubona ibicuruzwa bakeneye mugihe babikeneye.

3. Ubushobozi bwa R&D

Isoko ryiza cyane mubusanzwe rifite itsinda rikomeye R&D rishobora gukomeza kunoza ibicuruzwa no guteza imbere ibicuruzwa bishya. Suzhou Myland yakusanyije uburambe bukomeye mubushakashatsi no gushyira mu bikorwa Squalene kandi ibasha guha abakiriya inkunga ya tekiniki yumwuga nibisubizo.

4. Serivise y'abakiriya

Serivise nziza yabakiriya nikintu kidashobora kwirengagizwa muguhitamo uwaguhaye isoko. Suzhou Myland yibanda ku itumanaho n’abakiriya kandi irashobora gutanga serivisi yihariye ukurikije abakiriya bakeneye kugirango abakiriya babone uburambe bwiza mugihe cyo kugura.

5. Icyemezo no kubahiriza

Kugenzura niba abatanga isoko bafite ibyemezo bijyanye kandi kubahiriza ni ingingo zingenzi zo guhitamo. Suzhou Myland yemewe na ISO kandi yubahiriza ibipimo bya GMP (Good Manufacturing Practice), byemeza ko ibicuruzwa byayo bikurikiza uburyo bunoze bwo gucunga neza mugihe cyibikorwa.

Mu gusoza

Guhitamo neza isoko ya Squalene ni urufunguzo rwo kwemeza ubuziranenge n'umutekano. Suzhou Myland yahindutse amahitamo yizewe mu nganda n'ibicuruzwa byayo bifite isuku nyinshi, kugenzura ubuziranenge na serivisi z'umwuga. Waba uri uruganda rukora ibicuruzwa byuruhu, uruganda rwo kwisiga cyangwa abandi basaba inganda, Suzhou Myland irashobora kuguha ifu nziza ya squalene nziza kugirango ifashe ubuzima bwawe niterambere ryumwuga. Kubindi bisobanuro, nyamuneka sura urubuga rwemewe rwa Suzhou Mailun Biology.