Trigonelline HCl Niki kandi Kuki Ukwiye Kwitaho?

Mwisi yubuzima nubuzima bwiza, hakunze kwibandwaho kubintu bitandukanye bifite inyungu zitandukanye. Ikintu kimwe cyashimishije abantu mumyaka yashize ni Trigonelline HCl. Trigonelline hydrochloride ni alkaloide isanzwe iboneka mu bimera bitandukanye, cyane cyane imbuto za fenugreek n'ibishyimbo bya kawa. Nibikomoka kuri aside amine acide niacin kandi izwiho imiterere yihariye yimiti ituma ishobora gukorana na sisitemu zitandukanye yibinyabuzima mumubiri. "HCl" mu izina ryayo yerekeza ku miterere ya hydrochloride, yongerera imbaraga imbaraga za bioavailability, bigatuma umubiri woroha.

Kumenyekanisha ibicuruzwa

Trigonelline HCl(CAS: 6138-41-6) ni ifu yera-yera. Trigonelline HCl ni umunyu wakozwe nyuma ya reaction ya trigonelline na aside hydrochloric. Ibicuruzwa, imiterere yumunyu mubisanzwe ifite imbaraga zo gukomera no gutuza. Trigonelline, izwi kandi ku izina rya niacin betaine, kandi izina ryayo rya siyansi ni trimethylxanthine, ni azote irimo azote irimo alkaline igaragara nk'ifu ya kristaline yera kandi igashonga muri methanol n'amazi. Trigonelline nigice kinini cya alkaloide ya fenugreek kandi ifite ibikorwa bitandukanye byibinyabuzima, harimo antioxydeant, anti-inflammatory, hamwe no kugenzura isukari mu maraso. Hydrochloride ya Trigonelline nayo igaragaza ingaruka zisa mubijyanye na bioactivite, ariko irashobora kugira akarusho muri bioavailable bitewe nubushake bwayo bwiza.

Porogaramu

Isukari yo mu maraso

Ubushakashatsi bwerekanye ko mu mbeba ya diyabete yo mu bwoko bwa 2, trigonelline ishobora kugabanya isukari yo mu maraso hamwe n’urwego rwa insuline, ikongera igipimo cy’imikorere ya insuline, kandi ikongera uburemere bw’igifu, igipimo cy’uburemere bw’umubiri, hamwe n’uburemere bwa pancreas mu guteza imbere ingirabuzimafatizo ya beta no kugabanya insuline. . Ibirimo insuline, bityo bigabanye urugero rwisukari mu maraso.

Kurwanya gusaza

Ubushakashatsi bwerekana ko inyongera ya trigonelline ishobora kongera urwego rwa NAD + no kongera ibikorwa bya mito-iyambere, bityo bigafasha kunoza gusaza. Kurugero, muri nematode, trigonelline irashobora kugabanya umuvuduko wimitsi bitewe nimyaka kandi ikongerera igihe; imbeba, trigonelline irashobora kongera imbaraga mumitsi no kugabanya umunaniro mugihe cyo gusaza.

Kunoza imikorere yubwenge

Ubushakashatsi bwerekanye ko trigonelline ishobora kunoza imitekerereze y’imbeba zishaje mu guhagarika umusaruro w’ibintu bitera imbaraga no guteza imbere irekurwa rya neurotransmitter. Byongeye kandi, trigonelline irashobora kandi gutera imikurire yimikorere ya selile yumuntu neuroblastoma SK-N-SH, ishobora kuba ifitanye isano nuburyo bwayo bwo kunoza kwibuka.

Lipide yo mu maraso

Muri GK ubwoko bwa 2 imbeba za diyabete, trigonelline yagabanije serumu na hepatike triglyceride ya hepatike, igabanya ibikorwa bya synthase ya hepatike ya hepatike, kandi byongera hepatike karnitine palmitoyltransferase nibikorwa bya glucokinase.

Gukoresha inganda za Trigonelline HCl

Trigonelline ifite imirimo itandukanye ya physiologique, harimo antioxydeant, kugabanya isukari yamaraso, kwikuramo radicals yubusa, kunoza imikorere ya mitochondial, kongera imbaraga zimitsi, kugabanya kwangirika kwingirabuzimafatizo, kunoza imikorere yubwenge, nibindi. Ukurikije ibi, Trigonelline HCl ikoreshwa cyane Muri farumasi inganda, ikoreshwa nkibintu bikora mubiyobyabwenge.

Kugura Trigonelline HCl?

Mw'isi yimirire nubuzima bugezweho, Trigonelline HCl iragenda yitabwaho cyane kubwinyungu nyinshi zubuzima. Nka alkaloide isanzwe iboneka, Trigonelline HCl ikurwa cyane mubinyamisogwe n'ibimera bimwe na bimwe kandi ikoreshwa cyane mubicuruzwa byubuzima nibiribwa bikora. Hamwe n’abaguzi biyongera kubintu bisanzwe, isabwa ryifu ya Trigonelline HCl yo mu rwego rwo hejuru nayo iriyongera ku isoko,

Iyo uguze Trigonelline HCl, ubuziranenge nibyingenzi cyane. Ugomba kwemeza ko ugura kubatanga isoko bazwi batanga ibicuruzwa byiza.Mugihe ushakisha "trigonelline hydrochloride," menya neza niba ugenzura ibizamini byabandi hamwe nicyemezo kugirango umenye neza ibicuruzwa nimbaraga. Gusoma ibyasuzumwe byabakiriya birashobora kandi gutanga ubushishozi mubikorwa byibicuruzwa no kwizerwa kubagurisha.

1. Ubwiza bwibicuruzwa

Iyo uhisemo utanga isoko, ikintu cya mbere ugomba gusuzuma ni ubwiza bwibicuruzwa. Ifu yuzuye ya Trigonelline HCl ifata ibikorwa byibinyabuzima no gukora neza. Ifu ya Trigonelline HCl yatanzwe na Suzhou Myland yakorewe ibizamini byujuje ubuziranenge kugirango buri cyiciro cyibicuruzwa cyujuje ubuziranenge mpuzamahanga kandi cyemeza ubuziranenge.

2. Ubushobozi bwo gukora

Ubushobozi bwumusaruro bugira ingaruka muburyo butaziguye no kugemura. Suzhou Myland ifite ibikoresho byubuhanga n’ikoranabuhanga bigezweho bishobora guhuza ibikenerwa n’umusaruro rusange, byemeza ko abakiriya bashobora kubona ibicuruzwa bakeneye mugihe babikeneye.

3. Ubushobozi bwa R&D

Isoko ryiza cyane mubusanzwe rifite itsinda rikomeye R&D rishobora gukomeza kunoza ibicuruzwa no guteza imbere ibicuruzwa bishya. Suzhou Myland yakusanyije ubunararibonye mu bushakashatsi no gushyira mu bikorwa Trigonelline HCl kandi ibasha guha abakiriya inkunga ya tekinike yumwuga nibisubizo.

4. Serivise y'abakiriya

Serivise nziza yabakiriya nikintu kidashobora kwirengagizwa muguhitamo uwaguhaye isoko. Suzhou Myland yibanda ku itumanaho n’abakiriya kandi irashobora gutanga serivisi yihariye ukurikije abakiriya bakeneye kugirango abakiriya babone uburambe bwiza mugihe cyo kugura.

5. Icyemezo no kubahiriza

Kugenzura niba abatanga isoko bafite ibyemezo bijyanye kandi kubahiriza ni ingingo zingenzi zo guhitamo. Suzhou Myland yemewe na ISO kandi yubahiriza ibipimo bya GMP (Good Manufacturing Practice), byemeza ko ibicuruzwa byayo bikurikiza uburyo bunoze bwo gucunga neza mugihe cyibikorwa.

Nkumushinga wifu ya Trigonelline HCl, Suzhou Myland yatsindiye abakiriya benshi ibicuruzwa byayo bifite isuku nyinshi no kugenzura ubuziranenge. Isosiyete yiyemeje guha abakiriya ibikoresho byiza byo mu rwego rwo hejuru no kubafasha gutsinda mu nganda zabo.

Guhitamo neza Trigonelline HCl itanga ni urufunguzo rwo kwemeza ubuziranenge n'umutekano. Suzhou Myland yahindutse amahitamo yizewe mu nganda n'ibicuruzwa byayo bifite isuku nyinshi, kugenzura ubuziranenge na serivisi z'umwuga. Waba uri uruganda rukora ibicuruzwa byubuzima cyangwa uruganda rwibiryo, Suzhou Myland irashobora kuguha ifu nziza ya Trigonelline HCl ifasha ubuzima bwawe niterambere ryumwuga. Kubindi bisobanuro, nyamuneka sura urubuga rwemewe rwa Suzhou Myland.