Mwisi yisi ikura yinyongera, ifu ya magnesium alpha-ketoglutarate ifata abantu inyungu zayo. Alpha-ketoglutarate (AKG) nikintu gisanzwe kibaho mumubiri kigira uruhare runini mukuzenguruka kwa Krebs, ningirakamaro mukubyara ingufu. Iyo uhujwe na magnesium, minerval yingenzi izwiho inyungu nyinshi zubuzima, iyi fu iba inyongera ikomeye. Magnesium igira uruhare mu mibereho irenga 300 ya biohimiki mu mubiri, harimo imikorere yimitsi, neurotransmission nubuzima bwamagufwa.
Alpha-ketoglutarate (AKG mu magambo ahinnye), izwi kandi ku izina rya 2-oxoglutarate (2-OG), igira uruhare runini mu mikorere y'ibinyabuzima ya metabolisme y'ingufu na synthesis ya amino. Ntabwo igira uruhare runini mubikorwa bya okiside ya aside irike, aside amine na glucose, ahubwo ni nigicuruzwa cyibanze hagati ya acide tricarboxylic (TCA) cyinzira zubuhumekero, kikaba ari ngombwa kugirango ingufu zibanze zitange ubuzima. ibikorwa.
Mu myaka yashize, ubushakashatsi bwa siyansi bwerekanye ko AKG ari ikintu gikomeye cyo kurwanya gusaza metabolike. Ifite ingaruka zikomeye mu kwagura ubuzima no guteza imbere ubuzima mu kugenzura neza imikorere itandukanye ya fiyologiki yibinyabuzima.
AKG ntabwo ari isoko yingenzi yingirabuzimafatizo ya gastrointestinal kugirango ikore adenine nucleoside triphosphate (ATP), ariko kandi igira uruhare runini nkibibanziriza acide amine nka glutamate, glutamine na arginine.
Ubushakashatsi bwa siyansi bwerekana neza ko AKG ishobora guteza imbere mu buryo butaziguye cyangwa butaziguye uburyo bwo guhuza aside aside amine kandi ikagira uruhare rukomeye mu gukomeza kuringaniza aside amine mu mubiri. Nyamara, ingano ya AKG yakozwe mugihe cya metabolisme karemano yingirabuzimafatizo kugirango ihuze aside amine ikenewe akenshi biragoye guhaza ibyo umubiri ukeneye. Kubwibyo, ni ngombwa cyane kuzuza AKG binyuze muburyo bwo kurya.
Nigute alpha-ketoglutarate (AKG) yongerera ubuzima?
Alpha-ketoglutarate ifasha guhuza imitsi, gukiza ibikomere, kugabanya umuriro, nubundi buryo bwinshi bwo gutinza gusaza:
α-Ketoglutarate ni molekile ndende irashobora kwongerera igihe cyibinyabuzima bitandukanye (nka Caenorhabditis elegans, Drosophila melanogaster, nimbeba). α-Ketoglutarate (AKG) igira ingaruka zitandukanye muburyo butandukanye bwo gusaza (nka Table Epigenetics na mitochondrial dysfunction) bifite akamaro.
Nibintu bisanzwe biboneka mumubiri, ariko, urwego rwayo rugabanuka uko imyaka igenda ishira. Ifasha umubiri kwangiza no gufasha umubiri kurandura ammonia, nigicuruzwa cyimyanda ikorwa na protein metabolism kandi gishobora kwirundanya byoroshye mumubiri (uko urya proteine nyinshi, niko amoniya ikorwa).
Mugihe tugenda dusaza, biragoye cyane kumubiri gukuraho ammonia. Ammonia nyinshi yangiza umubiri. Alpha-ketoglutarate ifasha umubiri kwangiza no kurandura ibintu byangiza.
Itezimbere ubuzima bwa mitochondial kandi irashobora kuba amavuta ya mitochondria
Iyi ngingo kandi nimwe mumasoko yingufu za mitochondria kandi irashobora gukora AMPK, metabolism ikomeye ijyanye no kuramba.
Itanga kandi imbaraga nyinshi no kwihangana, niyo mpamvu bamwe mubakinnyi ndetse nabubaka umubiri bafata inyongera ya alpha-ketoglutarate igihe kirekire.
Ikiruta byose ni umutekano cyane, AKG ni igice cyinzira ya metabolike ingirabuzimafatizo zacu zibona imbaraga zibyo kurya.
Igenga intungamubiri za poroteyine no gukura kw'amagufwa
Alpha-ketoglutarate nayo igira uruhare mukubungabunga ubuzima bwingirangingo, hamwe namagufa yo munda. Muri metabolism selile, AKG nisoko yingenzi ya glutamine na glutamate, itera intungamubiri za poroteyine, ikabuza kwangirika kwa poroteyine mu mitsi, kandi ikagira amavuta akomeye ya metabolike ya selile gastrointestinal.
Glutamine ni isoko yingufu zubwoko bwose bwingirabuzimafatizo mu binyabuzima, bingana na 60% bya pisine yose ya aside amine. Kubwibyo, AKG, nkibibanziriza glutamine, nisoko nyamukuru yingufu za enterocytes hamwe na substrate ikunzwe kuri enterocytes.
Magnesium
Magnesium ni imyunyu ngugu ifite uruhare runini mu mubiri. Ifite uruhare mu myitwarire irenga 300, harimo ibijyanye no gutanga ingufu, synthesis ya protein, n'imikorere y'imitsi. Magnesium kandi ifasha kugumana imikorere isanzwe yimitsi, urugero rwisukari rwamaraso, no kugenzura umuvuduko wamaraso. Nubwo akamaro ka magnesium, abantu benshi ntibujuje ibyifuzo bya buri munsi bya magnesium, bigatuma habaho kubura magnesium bigira ingaruka kubuzima muri rusange.
Alpha-ketoglutarate
Alpha-ketoglutarate (AKG) nikintu gisanzwe kibaho kigira uruhare runini mukuzenguruka kwa Krebs, kikaba ari ngombwa mu guhumeka selile no kubyara ingufu. Ifite kandi uruhare muri metabolism ya aside amine na synthesis ya neurotransmitter. AKG yakozweho ubushakashatsi ku nyungu zishobora kubaho mu buzima butandukanye, harimo n'uruhare rwayo mu kuzamura imitsi, kunoza imikorere ya siporo, no gushyigikira ubuzima bwa metabolike.
Ingaruka ya synergiste ya magnesium na alpha-ketoglutarate
Magnesium alpha-ketoglutarate ni uruvange ruhuza magnesium na alpha-ketoglutarate, urufunguzo rwingenzi hagati yizunguruka ya Krebs (ruzwi kandi nka citric acide cycle), rukenewe kugirango ingirabuzimafatizo zitangwe ningirakamaro.
Iyo magnesium ihujwe na alpha-ketoglutarate, ibivuyemomagnesium alpha-ketoglutarate ifite umubare wibyiza bidasanzwe. Ingaruka ikomatanya hagati ya magnesium na AKG yongerera bioavailable yibintu byombi, byorohereza umubiri kubyakira no kubikoresha neza. Uku guhuza gukurura cyane cyane abakinnyi nabantu bashaka kunoza imikorere yumubiri no gukira.
Magnesium alpha-ketoglutarate isanzwe ikoreshwa nk'inyongera y'ibiryo, cyane cyane kubantu bashaka kongera ingufu, kuzamura ubuzima, cyangwa gushyigikira ubuzima muri rusange.
1. Kurema
Incamake: Creatine nimwe mubyongeweho ubushakashatsi cyane mubikorwa bya fitness, bizwiho ubushobozi bwo kubaka imbaraga nubwinshi bwimitsi.
Kugereranya: Mugihe creine yibanda cyane cyane kongera imbaraga zimitsi nubunini, ifu ya magnesium alpha ketoglutarate itanga inyungu nini za metabolike, harimo kubyara ingufu no gukira. Ku bakinnyi bashaka imbaraga ziturika, creine irashobora kuba ihitamo ryambere, ariko kubakinnyi bashaka inkunga ya metabolike muri rusange, AKG hamwe na magnesium irashobora kuba ingirakamaro.
2. BCAA (acide amashami aminide acide)
Incamake: Amashami ya aminide aciriritse arazwi cyane mubakinnyi kubera uruhare rwabo mugukiza imitsi no kugabanya ububabare bwimitsi iterwa na siporo.
Kugereranya: Amashami-aminide acide amashami afite akamaro mukugarura imitsi, ariko ntutange inkunga ya metabolike nka AKG. Mugihe amashami ya aminide acide amashami afasha mugusana imitsi, ifu ya magnesium alpha ketoglutarate yongerera ingufu ingufu no gukira muri rusange, bigatuma ihitamo neza kubantu bashaka kunoza imikorere no gukira.
3. L-karnitine
Incamake: L-karnitine ikoreshwa cyane mukugabanya ibinure no kunoza imikorere ya siporo mugutezimbere aside irike muri mitochondriya kugirango itange ingufu.
Kugereranya: L-Carnitine na AKG Magnesium Powder byombi bishyigikira imbaraga za metabolism, ariko babikora binyuze muburyo butandukanye. L-Carnitine yibanda cyane kuri okiside yibinure, mugihe AKG itanga inyungu nini zirimo gukira imitsi hamwe nubufasha bwubwenge. Kubashaka kongera ibinure mugihe bashyigikira ubuzima bwimitsi, guhuza byombi birashobora kuba byiza.
4.Omega-3 amavuta acide
Incamake: Omega-3s izwiho kurwanya anti-inflammatory nibyiza kumutima.
Kugereranya: Omega-3 yibanda ku kugabanya gucana no gushyigikira ubuzima bwimitsi yumutima, mugihe ifu ya Magnesium Alpha Ketoglutarate yibanda kubyara ingufu no kugarura imitsi. Kubantu bashaka kuzamura ubuzima bwabo muri rusange, guhuza ibi byongeweho byombi bitanga inzira yuzuye.
5.Multivitamine
Incamake: Multivitamine yagenewe kuzuza icyuho cyintungamubiri mumirire, itanga vitamine ningirakamaro.
Gereranya: Mugihe multivitamine itanga intungamubiri nyinshi, ntishobora gutanga inyungu zihariye za AKG na magnesium. Kubantu bibanda kumusaruro wingufu no kugarura imitsi, ifu ya magnesium alpha ketoglutarate irashobora kuba amahitamo menshi.
1. Kongera umusaruro w'ingufu
Imwe mu nyungu nyamukuru za Poweri ya Magnesium Alpha Ketoglutarate nuruhare rwayo mukubyara ingufu. Alpha-ketoglutarate ningirakamaro hagati yigihe cya Krebs, inzira imibiri yacu ihindura karubone, amavuta, na proteyine imbaraga. Iyo wongeyeho AKG, uzamura ubushobozi bwumubiri wawe kubyara ingufu neza. Ku rundi ruhande, Magnesium, ni imyunyu ngugu ifite uruhare runini mu myitwarire irenga 300 mu mubiri, harimo n'abagize uruhare mu guhinduranya ingufu. Iyo ikoreshejwe hamwe, AKG na magnesium bikorana hamwe kugirango hongerwe ingufu ingufu.
2. Kunoza imitsi
AKG yerekanwe gufasha kugabanya imitsi no gushyigikira intungamubiri za poroteyine, zikomeye mu gusana imitsi no gukura. Byongeye kandi, magnesium izwiho imitsi iruhura imitsi. Ifasha kwirinda kurwara no kurwara, bigatuma inzira yo gukira yoroshye. Mugushyiramo Magnesium Alpha Ketoglutarate Ifu mumikorere yawe nyuma yimyitozo, urashobora kugabanya ububabare bwimitsi hanyuma ugasubira mubikorwa byihuse.
3. Kongera imikorere yubwenge
Ubushakashatsi bwerekana ko AKG ishobora gushyigikira ubuzima bwubwonko iteza imbere umusaruro wa neurotransmitter no kongera plastike ya synaptic, ifite akamaro kanini mukwiga no kwibuka. Magnesium nayo igira uruhare runini mumikorere yo kumenya. Byahujwe no kunoza imyumvire, kugabanya amaganya, no kuzamura ubuzima bwubwonko muri rusange. Muguhuza AKG na magnesium, uburambe bwongereye ubwenge bwubwenge, kongera ibitekerezo, hamwe nubushobozi bwongerewe bwo gukemura ibibazo.
4. Shigikira gusaza neza
Mugihe tugenda dusaza, imibiri yacu igira impinduka zitandukanye zishobora kugira ingaruka kubuzima muri rusange no kumererwa neza. Alpha-ketoglutarate imaze kwitabwaho kubishobora kuba birwanya gusaza. Ubushakashatsi bumwe bwerekana ko AKG ishobora gufasha kuramba mugushigikira ubuzima bwakagari no kugabanya imbaraga za okiside. Magnesium nayo ni ngombwa mu gukomeza gusaza neza. Ifasha kugenzura imikorere itandukanye yumubiri, harimo umuvuduko wamaraso, imikorere yimitsi, nubuzima bwamagufwa. Muguhuza AKG na magnesium, urashobora gushobora gushyigikira umubiri wawe usaza, ukongera imbaraga nubuzima bwiza uko usaza.
5. Gutera amagara nubufasha bwibiryo
Ubuzima bwigifu nifatizo ryubuzima rusange, kandi ifu ya magnesium alpha ketoglutarate ifu irashobora kugira uruhare mugushigikira sisitemu nziza. AKG byagaragaye ko igira ingaruka nziza kuri mikorobe yo mu nda, igatera imbere gukura kwa bagiteri zifite akamaro mugihe zirwanya imiterere yangiza. Ibi bivamo kunoza igogora no gufata neza intungamubiri. Magnesium kandi ifasha mubuzima bwigifu ifasha kugenga amara no kwirinda kuribwa mu nda. Iruhura imitsi yinzira yigifu kandi igatera igogorwa ryoroshye.
1. Ubuziranenge nubuziranenge
Iyo uhisemo inyongera, ubuziranenge ni ngombwa. Shakisha ibicuruzwa bitarimo kuzuza, amabara yubukorikori hamwe nububiko. Ifu nziza cyane ya magnesium alpha ketoglutarate ifu igomba kuba irimo igice kinini cyibintu bikora. Reba ibyemezo byabandi-bipimisha kugirango umenye ibicuruzwa byageragejwe kubwera nimbaraga.
2. Inkomoko y'ibikoresho fatizo
Inkomoko yibigize irashobora kugira ingaruka zikomeye kumiterere yinyongera yawe. Kora ubushakashatsi kubakora kugirango umenye neza ko bakoresha ubuziranenge, bioavailable AKG na magnesium. Reba nanone niba ibiyigize biva mubisanzwe cyangwa bihujwe muri laboratoire.
3. Ingano hamwe nibitekerezo
Ibicuruzwa bitandukanye birashobora kuba birimo intumbero zitandukanye za AKG na magnesium. Witondere kugenzura buri gipimo kiri kuri label kugirango umenye neza ko cyujuje intego zubuzima. Ingano isabwa irashobora gutandukana ukurikije ibyo buri muntu akeneye, birasabwa rero kubaza inzobere mubuzima mbere yo gutangira inyongera nshya.
4. Gutegura nibindi bintu byongeweho
Ifu imwe ya magnesium alpha ketoglutarate ifu irashobora kuba irimo ibindi bintu byagenewe kongera imbaraga cyangwa gutanga inyungu zinyongera. Kurugero, amata amwe arashobora kuba arimo vitamine B6, ishobora gufasha kwinjiza magnesium. Ariko rero, witondere ibicuruzwa byongeramo ibintu byinshi kuko bishobora kugora formulaire kandi ntibishobora kuba nkenerwa kubyo ukeneye.
5. Icyamamare
Ibiranga ubushakashatsi mbere yo kugura. Ibirangantego bizwi bifite izina ryiza birashoboka cyane kubyara inyongeramusaruro nziza. Shakisha abakiriya no gutanga ubuhamya kugirango umenye uburambe bwabandi. Ibicuruzwa bisobanutse kubyerekeye isoko yabyo, uburyo bwo gukora no kugerageza muri rusange biringirwa.
6. Ingingo y'ibiciro
Mugihe igiciro kitagomba kuba ikintu cyonyine gifata umwanzuro, kubona ibicuruzwa bihuye na bije yawe ni ngombwa. Witondere amahitamo make cyane kuko ashobora guhungabanya ubuziranenge. Gereranya ibiciro biva mubirango bizwi kugirango ubone uburinganire hagati yubuziranenge kandi buhendutse.
Myland Pharm & Nutrition Inc. yatangiye gukora ubucuruzi bwongera imirire kuva mu 1992. Nisosiyete ya mbere mu Bushinwa yateje imbere kandi igacuruza imbuto zinzabibu.
Hamwe nuburambe bwimyaka 30 kandi itwarwa nubuhanga buhanitse hamwe ningamba zinoze cyane R&D, isosiyete yateje imbere ibicuruzwa bitandukanye byapiganwa kandi ihinduka ubumenyi bwa siyanse yubuzima bushya, synthesis gakondo hamwe na serivise zikora inganda.
Mubyongeyeho, Myland Pharm & Nutrition Inc nayo ikora FDA yanditswe. Ibikoresho bya R&D byikigo, ibikoresho byububiko, nibikoresho byisesengura nibigezweho kandi nibikorwa byinshi, kandi birashobora gukora imiti kuva kuri miligarama kugeza kuri toni mubipimo kandi ikubahiriza ibipimo bya ISO 9001 nibisobanuro bya GMP.
Ikibazo: Ifu ya Magnesium Alpha-Ketoglutarate ni iki?
Igisubizo: Magnesium Alpha-Ketoglutarate Ifu ninyongera yimirire ihuza magnesium na alpha-ketoglutarate, uruganda rugira uruhare mukuzenguruka kwa Krebs, rukaba rukenewe mukubyara ingufu mumubiri. Iyi nyongera ikoreshwa kenshi mugushigikira ubuzima bwimikorere, kuzamura imikorere ya siporo, no guteza imbere imibereho myiza muri rusange.
Ikibazo: Ni izihe nyungu zo gufata ifu ya Magnesium Alpha-Ketoglutarate?
Igisubizo: Inyungu zimwe zishoboka za Magnesium Alpha-Ketoglutarate Ifu irimo:
Umusaruro wongerewe ingufu: Gushyigikira inzinguzingu ya Krebs, ifasha muguhindura intungamubiri mu mbaraga.
Recovery Kugarura imitsi: Birashobora gufasha kugabanya ububabare bwimitsi no kunoza igihe cyo gukira nyuma yimyitozo.
Health Ubuzima bw'amagufa: Magnesium ni ngombwa mu kubungabunga amagufwa meza kandi irashobora gufasha kwirinda ostéoporose.
Imikorere yo kumenya: Ubushakashatsi bumwe bwerekana ko bushobora gushyigikira ubuzima bwubwonko nibikorwa byubwenge.
Support Inkunga ya Metabolic: Irashobora gufasha mugutunganya inzira ya metabolike kandi irashobora gufasha mugucunga ibiro.
Inshingano: Iyi ngingo ni iyamakuru rusange gusa kandi ntigomba gusobanurwa nkinama zose zubuvuzi. Amwe mumakuru yohereza amakuru aturuka kuri enterineti kandi ntabwo ari umwuga. Uru rubuga rufite inshingano zo gutondeka, gutunganya no guhindura ingingo. Intego yo gutanga amakuru menshi ntabwo bivuze ko wemera ibitekerezo byayo cyangwa kwemeza ukuri kwibirimo. Buri gihe ujye ubaza inzobere mu buzima mbere yo gukoresha inyongera cyangwa guhindura ibintu byubuzima bwawe.
Igihe cyo kohereza: Ukwakira-10-2024
