J-147 uruganda rukora ifu CAS No.: 1146963-51-0 99.0% isuku min. kubintu byongeweho
Ibipimo byibicuruzwa
| Izina ryibicuruzwa | 2,2,2-Trifluoroacetic aside 1- (2,4-DiMethylphenyl) -2 - [(3-Methoxyphenyl) Methylene] hydrazide] |
| Irindi zina | J-147, J147 |
| URUBANZA No. | 1146963-51-0 |
| Inzira ya molekulari | C18H17F3N2O2 |
| Uburemere bwa molekile | 350.33 |
| Isuku | 99% |
| Kugaragara | Ifu yera |
| Gupakira | 1kg kumufuka |
| Gusaba | nootropics |
Kumenyekanisha ibicuruzwa
J-147 ni imbaraga zikomeye mu kanwa zikora neuroprotectant zikomoka cyane cyane kuri curcumin, ingirakamaro muri turmeric. Bitandukanye na curcumin, irenga inzitizi yamaraso-ubwonko neza. Muri byo, J-147 ikora ihuza na ATP synthase. Umusaruro mwinshi wa ATP ujyanye no gusaza. Usibye kongera urwego rwa neurotransmitters NGF na BDNF, J-147 irashobora kugenzura ibi. Byongeye kandi, J-147 ibuza monoamine oxydease B na transport ya dopamine. Guteza imbere ubwonko bwongera urwego rwo gukura kwimitsi (NGF) hamwe nubwonko bukomoka mubwonko (BDNF). Icy'ingenzi cyane, J-147 irashobora guteza imbere imikurire yimitsi mishya, kongera ubushobozi bwubwonko bwo kwiga no kwibuka, no kunoza imikorere yubwenge.
Ikiranga
(1) Isuku ryinshi: J-147 irashobora kubona ibicuruzwa byera cyane binyuze mu gutunganya umusaruro. Isuku ryinshi risobanura bioavailable nziza hamwe na reaction nkeya.
(2) Umutekano: J-147 byagaragaye ko ifite umutekano ku mubiri w'umuntu.
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Porogaramu
J-147 nuruvange rwubukorikori rufite uburyo bwibanze bwibikorwa birimo kuzamura mitochondial, bityo bigatuma ingufu zitanga ingufu kurwego rwa selire. J-147 yashizweho kugirango yongere ubushobozi bwubwonko bwo gusana no kwirinda ibyangizwa nimyaka bitewe no kunoza imikorere ya mito-iyambere. Byongeye kandi, J-147 yerekana ibintu byingenzi birwanya anti-inflammatory na antioxydeant, bikarushaho kongera ingaruka ziterwa na neuroprotective. J-147 irashobora guteza imbere imikurire yingirabuzimafatizo nshya, kongera ubushobozi bwubwonko bwo kwiga no kwibuka, no kunoza imikorere yubwenge.
