N-Boc-O-Benzyl-D-serine yifu ya CAS No.:47173-80-8 98% isuku min. kubunzi
Ibipimo byibicuruzwa
Izina ryibicuruzwa | N-Boc-O-Benzyl-D-serine |
Irindi zina | N-Boc-O-benzyl-D-serine; Boc-O-benzyl-D-serine; O-Benzyl-N- (tert-butoxycarbonyl) -D-serine; Boc- (R) -2-amino-3-acide benzyloxypropionic; Boc-D-Ser (Bzl) -OH; Nat.-Boc-O-benzyl-D-serine; N-tert-butyloxycarbonyl-O-benzyl-D-serine; Nalpha-t-butoxycarbonyl-O-benzyl-D-serine; |
URUBANZA No. | 47173-80-8 |
Inzira ya molekulari | C15H21NO5 |
Uburemere bwa molekile | 295.33 |
Isuku | 98% |
Gupakira | 1kg / umufuka; 25kg / ingoma |
Gusaba | Abahuza |
Kumenyekanisha ibicuruzwa
N-Boc-O-Benzyl-D-serine ni uruganda rwitabiriwe cyane mubijyanye na chimie organic nubushakashatsi bwa farumasi. Uru ruganda, ruzwi kandi ku izina rya Boc-D-serine, rukomoka kuri aside amine D-serine kandi rukoreshwa cyane mu gusanisha imiti itandukanye na molekile ya bioactive. N-Boc-O-Benzyl-D-serine ni ifu yera ya kirisita yera yera kandi idashonga cyane mumazi kandi igashonga mumashanyarazi nka methanol na Ethanol. Nibikomoka kuri D-serine, ikaba ari aside amine-proteyine idafite aside igira uruhare runini muri sisitemu yo hagati y’imitsi nka co-agonist ya reseptor ya N-methyl-D-aspartate (NMDA). Amatsinda ya N-Boc (tert-butoxycarbonyl) na O-Benzyl mu kigo akora nk'itsinda ririnda, bigatuma habaho guhitamo aside amine mugihe cyo guhuza imiti.N-Boc-O-Benzyl-D-serine ikoreshwa cyane cyane nka a kubaka inyubako muri synthesis ya peptide na peptidomimetics. Peptide ni iminyururu ngufi ya aside amine igira uruhare runini mubikorwa byibinyabuzima kandi ishishikajwe cyane no kuvumbura ibiyobyabwenge niterambere. Mugushyiramo N-Boc-O-Benzyl-D-serine muburyo bwa peptide, abahanga mu bya shimi barashobora guhindura imiterere nibikorwa bya peptide bivamo, bikabigira igikoresho cyingirakamaro mugushushanya imiti yimiti mishya. Byongeye kandi, N-Boc-O-Benzyl-D-serine ikoreshwa mugutegura abahuza imiti nibikoresho bikora bya farumasi (APIs). Imyitwarire yayo itandukanye kandi ihujwe nuburyo butandukanye bwimiti ituma iba ikintu cyashakishijwe muguhuza molekile zigoye zifite ubushobozi bwo kuvura.
Ikiranga
(1) Isuku ryinshi: N-Boc-O-Benzyl-D-serine irashobora kubona ibicuruzwa bifite isuku nyinshi binyuze mu gutunganya umusaruro. Isuku ryinshi risobanura bioavailable nziza hamwe na reaction nkeya.
(2) Umutekano: Umutekano mwinshi, reaction nkeya.
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Porogaramu
Kwinjiza N-Boc-O-Benzyl-D-serine muri molekile yibiyobyabwenge byagaragaye ko bitanga imiti yifuzwa ya farumasi na farumasi. Peptidomimetics ikomoka kuri N-Boc-O-Benzyl-D-serine yerekanye ituze ryiyongera, bioavailable, hamwe nintego yihariye, bituma baba abakandida basezerana kuvura indwara zitandukanye, harimo kanseri, indwara zandura, nindwara zifata ubwonko.Ikindi kandi, ubushobozi guhitamo guhitamo guhitamo N-Boc-O-Benzyl-D-serine ituma habaho guhuza neza abakandida ibiyobyabwenge, bigahindura imikorere yabo hamwe numwirondoro wabo.