Uburyo Aniracetam ishobora kongera ubushobozi bwo kwibuka no kunoza imikorere y'ubwenge

Aniracetam ni umuti wa nootropic wo mu muryango wa piracetam ushobora kongera kwibuka, kongera kwibanda ku bintu, no kugabanya imihangayiko n'ihungabana. Hari ibihuha bivuga ko ushobora kongera guhanga udushya.

Aniracetam ni iki?

Aniracetambishobora kongera ubushobozi bwo gutekereza no kunoza amarangamutima.

Aniracetam yavumbuwe mu myaka ya 1970 n'ikigo cy'imiti cyo mu Busuwisi cyitwa Hoffman-LaRoche, ikaba igurishwa nk'umuti utangwa na muganga mu Burayi ariko ntigenzurwa muri Leta Zunze Ubumwe za Amerika, Kanada n'Ubwongereza.

Aniracetam isa na piracetam, nootropic ya mbere ya sintetike, kandi yabanje gukorwa nk'ubundi buryo bukomeye.

Aniracetam iri mu bwoko bwa nootropics bwa piracetam, ari na zo mvange z’ibinyabutabire bya sintetike bifite imiterere isa n’iya chimique n’uburyo bw’imikorere.

Kimwe n'izindi piracetam, Aniracetam ikora cyane cyane mu kugenzura ikorwa n'irekurwa ry'uturemangingo tw'ubwonko n'ibindi bintu bitera ubwonko.

Inyungu n'ingaruka bya Aniracetam

Nubwo hari ubushakashatsi buke ku bantu kuri aniracetam, imaze imyaka ibarirwa muri za mirongo yigwaho cyane, kandi ubushakashatsi butandukanye ku nyamaswa busa n’aho bushyigikira akamaro kayo nk’umuti uvura indwara zanduzanya.

Aniracetam ifite ibyiza n'ingaruka nyinshi byagaragaye.

Kongera ubushobozi bwo kwibuka no kwiga

Kuba Aniracetam ikora nk'umuti wongera ubushobozi bwo kwibuka bishyigikiwe n'ubushakashatsi bwerekana ko ishobora kunoza imikorere y'ubwonko ndetse ikanagabanya ikibazo cyo kwangirika k'ubwonko.

Ubushakashatsi bumwe bwakorewe ku bantu bazima bwagaragaje ko aniracetam yazamuye ibice bitandukanye byo kwibuka, harimo kumenya amaso, imikorere y'imitsi, n'imikorere y'ubwenge muri rusange.

Ubushakashatsi ku nyamaswa bwagaragaje ko Aniracetam ishobora kongera ubushobozi bwo kwibuka binyuze mu kugira ingaruka nziza ku rugero rwa acetylcholine, serotonin, glutamate, na dopamine mu bwonko.

Ubushakashatsi buherutse gukorwa bwagaragaje ko aniracetam itagize ingaruka nziza ku mbeba zikuze zifite ubuzima bwiza, bigaragaza ko ingaruka za aniracetam zishobora kugarukira gusa ku bafite ikibazo cyo kutamenya neza.

Kunoza uburyo bwo kwibanda no kwibanda ku bintu

Abantu benshi bafata Aniracetam nk'imwe mu miti myiza ya nootropics yo kunoza uburyo umuntu yibanda ku kintu kimwe no kwibanda ku kintu kimwe.

Nubwo nta bushakashatsi bwakozwe ku bantu kuri iki gice cy’iyi ngirabuzimafatizo, ingaruka zayo zagaragajwe neza kuri acetylcholine, dopamine, n’izindi ngirabuzimafatizo z’ingenzi zishyigikira cyane iki gitekerezo.

Aniracetam kandi ikora nka ampakin, itera imbaraga receptors za glutamate zifasha mu gukora inyigo no mu mikorere y'ubwonko.

Gabanya imihangayiko

Imwe mu miterere igaragara ya Aniracetam ni ingaruka zayo zo guhangayika (kugabanya imihangayiko).

Ubushakashatsi ku nyamaswa bwagaragaje ko aniracetam igira akamaro mu kugabanya imihangayiko no kongera imikoranire mu mibanire y'abantu mu mbeba, bishoboka ko binyuze mu guhuza ingaruka za dopaminergic na serotonergic.

Kugeza ubu nta bushakashatsi buri gukorwa bwibanda ku ngaruka za aniracetam ku bantu ku mitekerereze mibi. Icyakora, igerageza rimwe ryakozwe ku ikoreshwa ryayo mu kuvura indwara yo kwiheba ryagaragaje ko abitabiriye gufata Aniracetam bagabanutse imihangayiko.

Abakoresha benshi bavuga ko bumva bafite impungenge nke nyuma yo gufata Aniracetam.

Imiterere y'imiti igabanya kwiheba

Aniracetam yagaragaye kandi ko ari umuti uvura indwara zo kwiheba, ugabanya cyane kudashobora kugenda bitewe n'imihangayiko ndetse n'imikorere mibi y'ubwonko ijyana no gusaza.

Kumenya niba imiterere y’imiti igabanya ubukana yabonetse mu bushakashatsi ku nyamaswa ireba abantu ntibiragaragazwa.

Imiterere ishobora gutuma aniracetam igabanya ubukana bw'indwara zo mu mutwe ishobora guterwa no kwiyongera kw'ikwirakwizwa rya dopaminergic hamwe no gukurura acetylcholine receptor.

Kuvura indwara yo kwiheba

Imwe mu nyigo nke zakozwe ku bantu kuri aniracetam igaragaza ko ishobora kuba umuti mwiza ku bantu bafite ikibazo cyo kwiheba.

Abarwayi ba dementia bavuwe na aniracetam bagaragaje ubushobozi bwo gutekereza neza, imikorere myiza, kandi bagaragaje ko amarangamutima yabo n'amarangamutima yabo byarushijeho kwiyongera.

uko bikora

Uburyo nyabwo bwo gukora kwa Aniracetam ntiburasobanuka neza. Nyamara, ubushakashatsi bwakozwe mu myaka myinshi bwagaragaje uburyo igira ingaruka ku byiyumvo no ku mitekerereze binyuze mu bikorwa byayo mu bwonko no mu bwonko bwo hagati.

Aniracetam ni ikinyabutabire gishongesha ibinure, gishyirwa mu mwijima, kikanyuzwa vuba mu mubiri wose. Bizwiho kwambuka umupaka w'amaraso n'ubwonko vuba cyane, kandi abagikoresha bakunze kuvuga ko bumva ingaruka zacyo mu minota 30 gusa.

Aniracetam yongera ikorwa ry'uturemangingo twinshi tw'ingenzi mu bwonko tujyanye n'amarangamutima, kwibuka no kumenya:

Acetylcholine – Aniracetam ishobora kunoza imikorere y’ubwonko muri rusange binyuze mu kongera imikorere muri sisitemu ya acetylcholine, igira uruhare runini mu kwibuka, kwita ku bintu, kwihuta mu kwiga, n’izindi nzira zo gutekereza. Ubushakashatsi ku nyamaswa bwerekanye ko ikora binyuze mu gufatanya na receptors za acetylcholine, ikabuza receptor desensitization, kandi ikarushaho gutuma acetylcholine irekurwa muri synaptic.

Dopamine na Serotonin – Byagaragaye ko Aniracetam yongera urugero rwa dopamine na serotonin mu bwonko, bityo ikagabanya kwiheba, yongera imbaraga, kandi ikagabanya imihangayiko. Mu gufatanya na dopamine na serotonin receptors, Aniracetam ibuza gusenyuka kw'izi neurotransmitters z'ingenzi kandi ikagarura urugero rwiza rwa byombi, bigatuma yongera amarangamutima neza kandi ikagira ingaruka ku mitekerereze.

Kohereza Glutamate – Aniracetam ishobora kugira ingaruka zidasanzwe mu kunoza ububiko bw'amakuru no kuyabika kuko yongera kohereza glutamate. Mu guhuza no gukangura AMPA na kainate receptors (receptors za glutamate zifitanye isano rya hafi no kubika amakuru no gukora ububiko bushya), Aniracetam ishobora kongera ubushobozi bwo gutera imitsi, cyane cyane imbaraga z'igihe kirekire.

Igipimo

Buri gihe ni byiza gutangirana n'umuti muto cyane kandi ukongera buhoro buhoro uko bikenewe.

Nkuko bigenda ku miti myinshi ya nootropic mu muryango wa Piracetam, imikorere ya Aniracetam ishobora kugabanuka bitewe no gukabya.

Kubera ko igihe cyayo cyo kumara igice cy’ubuzima ni gito, isaha imwe cyangwa eshatu gusa, dose zisubirwamo zishobora gukenerwa kugabanywa kugira ngo ingaruka zikomeze.

Agace

Kimwe na piracetam nyinshi, Aniracetam ikora neza yonyine cyangwa ivanze n'indi miti ya nootropic. Dore bimwe mu bikunze kugaragara kuri Aniracetam ugomba gutekerezaho.

Aniracetam na Choline Stack

Kongeraho Choline akenshi ni byiza iyo ufata piracetam nka aniracetam. Choline ni intungamubiri y'ingenzi tuvana mu mirire yacu kandi ni yo ibanziriza acetylcholine, ishinzwe imikorere itandukanye y'ubwonko nko kwibuka.

Kongeraho isoko ya choline nziza kandi iboneka mu mubiri, nka alpha-GPC cyangwa citicoline, bituma habaho ibikoresho bikenewe byo gukora acetylcholine, bityo bigatanga ingaruka zayo za nootropic.

Iyi gahunda ni ingenzi cyane cyane iyo ufata aniracetam, kuko ikora igice kimwe mu gutuma sisitemu ya cholinerike ikora neza. Kongeramo choline bituma habaho choline ihagije mu mubiri kugira ngo yongere ingaruka za aniracetam mu gihe bigabanya ingaruka mbi zishobora guterwa na acetylcholine idahagije, nko kubabara umutwe.

Agasanduku ka PAO

Uruvange rwa PAO, ari rwo ruvange rw’amagambo ahinnye ya Piracetam, Aniracetam, na Oxiracetam, ni uruvange rusanzwe rukubiyemo guhuza iyi miti itatu izwi cyane ya nootropics.

Gushyira Aniracetam hamwe na Piracetam na Oxiracetam byongera ingaruka z'ibintu byose kandi bishobora kongera igihe cyabyo. Kongeramo piracetam bishobora kandi kongera imiterere ya aniracetam yo kurwanya indwara ziterwa no guhagarika umutima no guhangayika. Nkuko byavuzwe mbere, muri rusange ni byiza gushyiramo isoko ya choline.

Mbere yo kugerageza guhuza ibintu nk'ibi, ni byiza ko ubanza kumenyera ibice bimwe na bimwe mbere yo kubihuza. Tekereza kuri ubu buryo nyuma yo kumenya ingaruka zabyo n'uko ubyitwaramo.

Wibuke ko iyo ufata Piracetam cyangwa nootropics muri rusange hamwe, ugomba gufata dose ntoya ugereranije n'iyo ufata imwe imwe, kuko imiti myinshi ya nootropics igira ingaruka nziza ku bufatanye.