Niki ukeneye kumenya kuri palmitoylethanolamide (PEA)?

Palmitoylethanolamide (PEA) ni aside isanzwe iboneka aside amide yakwegereye ibitekerezo kubuzima bwiza. Uru ruganda ruboneka mu ngingo zitandukanye mu mubiri, kandi ubushakashatsi bwerekana ko palmitamideethanol (PEA) ishobora kugabanya uburibwe, kugabanya ububabare, kandi ishobora no guteza imbere ubuzima bwo munda no gutinda gusaza. Irashobora kugira inyungu zitandukanye mubuzima. Ibikurikira bizasuzuma ibyiza byubuzima bwa palmitoylethanolamide (PEA), uko ikora kumubiri wumuntu, nuburyo bwo kubona palmitoylethanolamide nziza (PEA).

Palmitoylethanolamide (PEA) ni iki?

Palmitoylethanolamide (PEA) ni ibisanzwe bibaho endocannabinoid-imeze nkibintu bizwi kubera imiterere idakira ya analgesic na anti-inflammatory. Usibye guhuzwa n'umubiri, PEA iboneka mu biribwa bitandukanye birimo: foromaje, umuhondo w'igi, inyama, amata, ibishyimbo, soya lecithine.

wari ubizi? Iyo umubiri uhuye nibibazo, nko gukomeretsa cyangwa gutwikwa, urwego rwa PEA ruhinduka kugirango rukomeze homeostasis.

Nigute palmitoylethanolamide igira ingaruka kumubiri wumuntu?

Abahanga ntibarasobanukirwa neza nuburyo bwibikorwa bya palmitoylethanolamide. Nubwo bimeze bityo ariko, tugeze kure, tubikesha Professor Rita Levi-Montalcini, mu 1992-1996 wasobanuye uburyo rusange bwibikorwa bya palmitoylethanolamide. Kuva icyo gihe, yakomeje kwiga ku ngaruka za palmitoylethanolamide ku bubabare bwa neuropathique na allergie.

Palmitoylethanolamide irashobora kuzana inyungu enye zubuzima kubantu:

Kuraho igisubizo kibabaza.

Kugabanya ibikorwa bya mast selile (allergie).

Komeza ibikorwa bya sisitemu ya endogenous.

Kora reseptor zihariye mumubiri.

Nigute PEA ikora ingaruka zayo zo kurwanya inflammatory no analgesic?

Inyungu zubuzima bwa PEA zirimo ingaruka kumubiri urinda indwara, cyane cyane mubwonko. PEA irashobora gufasha kugabanya umusaruro wibintu bitera umuriro. Nyamara, PEA ikora cyane cyane kubyakira kuri selile, bigenzura ibintu bitandukanye byimikorere ya selile. Aba reseptors bita PPARs. PEA nibindi bikoresho bifasha gukora PPAR birashobora kugabanya ububabare kandi birashobora no kongera metabolisme mu gutwika amavuta, serum triglyceride yo hasi, kongera cholesterol ya serumu HDL, kunoza isukari yamaraso, no gufasha kugabanya ibiro.

Inyungu za Palmitoylethanolamide

Bitewe n'ingaruka zacyo zo kurwanya no kurwanya inflammatory, ubushakashatsi bwerekana ko PEA ishobora gufasha mu bihe bitandukanye bijyanye n'ububabare, nka fibromyalgia, sciatica, na osteoarthritis.

1. Kuraho ububabare nigisubizo cyo gutwika

Ububabare budashira nikibazo gikomeye cyibasiye abarwayi kwisi yose, kandi uko abaturage basaza, iki kibazo kizarushaho gukomera. Imwe mumikorere ya palmitoylethanolamide nuko ishobora gufasha kugabanya ububabare no gutwikwa. palmitoylethanolamide ikorana na reseptor ya CB1 na CB2, nibintu byingenzi bigize sisitemu ya endogenous. Sisitemu ishinzwe kubungabunga homeostasis cyangwa kuringaniza mumubiri.

Iyo habaye igikomere cyangwa igisubizo kibabaje, umubiri urekura endogenous hemp compound kugirango ifashe kugenzura ubudahangarwa bw'umubiri. palmitoylethanolamide irashobora gufasha kongera urugero rwimisemburo ya endogenous mumubiri, bityo bikagabanya ububabare numuriro.

Byongeye kandi, palmitoylethanolamide irashobora kugabanya irekurwa ryimiti ikongora kandi igabanya ibisubizo byubwonko bwa neurologiya. Izi ngaruka zituma palmitoylethanolamide igikoresho gishobora gufasha kugabanya ububabare nibisubizo byumuriro. Ubushakashatsi bwerekana ko palmitoylethanolamide ishobora no kuba ingirakamaro kububabare bwa sciatica na syndrome ya carpal.

2. Fibromyalgia

Ubushakashatsi bwinshi bwerekana ko PEA ishobora gufasha kugabanya ibimenyetso bya fibromyalgia, indwara idakira y’imitsi itera ububabare bukabije. Iyo ikoreshejwe nk'umugereka w'ubuvuzi gakondo, gufata PEA bigabanya ubukana bw'ububabare kandi bikazamura ubuzima bwiza mugihe runaka. Nk’ubushakashatsi bumwe, gufata PEA amezi atatu byagabanije cyane ububabare kubantu barwaye fibromyalgia.

3. Kubabara umugongo

Ubushakashatsi bwibanze bwerekana ingaruka zishobora kuba PEA kubabara umugongo. Ubushakashatsi bwakozwe mu mwaka wa 2017 bwerekanye ko PEA yagabanije ubukana bw’abarwayi bafite syndrome yo kubaga umugongo.

Abantu barwaye sciatica, ububabare buturuka kumugongo wo hepfo ukuguru kumwe cyangwa amaguru yombi, nabo barashobora kubona ihumure nyuma yo gufata PEA. Ikigeragezo cyateganijwe, kabiri-gihumye, igenzurwa na platbo yize ku ngaruka za PEA nini- na nkeya ya PEA na placebo. Ububabare bwagabanutseho hejuru ya 50% mumatsinda menshi. Nubwo igipimo gito cya PEA kitageze ku kigero kimwe cyo kugabanya ububabare nkubunini bukabije, dosiye zombi zagize akamaro kanini kuruta umwanya wa placebo.

4. Osteoarthritis

PEA irashobora kugirira akamaro abantu barwaye osteoarthritis, indwara irangwa no kwangirika kwa karitsiye hamwe namagufwa. Abitabiriye ubushakashatsi bumwe bakiriye PEA bagize iterambere ryinshi muburengerazuba bwa Ontario na McMaster Universite Osteoarthritis Index (WOMAC) ugereranije nitsinda rya placebo. WOMAC ni ikibazo cyagenewe gusuzuma imiterere n'ibimenyetso (urugero, ububabare, gukomera, imikorere y'umubiri) ku barwayi bafite ivi n'ikibuno osteoarthritis.

Ubundi bushakashatsi bwakozwe n’abarwayi bafite ububabare bwigihe gito (TMJ) bujyanye na osteoarthritis bwerekanye ko inyongera ya PEA yazamuye cyane ububabare nyuma yiminsi 14 ugereranije na ibuprofen. Itsinda ryahaye PEA muminsi 14 ryerekanye iterambere ryinshi mugukingura umunwa ntarengwa (igipimo cyo kugabanya ububabare) kuruta itsinda rya ibuprofen.

5. Ububabare bwa Neuropathique

Ubushakashatsi bwibanze no gupima inyamaswa byerekana ko PEA ishobora gufasha mububabare bwa neuropathique (biterwa no kwangirika kwimitsi itwara ubutumwa hagati yubwonko nu mugongo), cyane cyane kubantu bafite syndrome ya carpal tunel, neuropathie diabete, chimiotherapie Abantu bafite neuropathie periferique, karande ububabare bwa pelvic, nububabare bujyanye nubwonko na sclerose nyinshi. Ibindi bigeragezo byamavuriro birakenewe kugirango hamenyekane imikorere ya PEA mugukemura ububabare bwa neuropathique.

6. Gusaza neza

Gutinda gusaza nintego yagaciro keza gakurikiranwa nabahanga benshi kwisi. Palmitoylethanolamide ifatwa nk'inyongera irwanya gusaza ishobora gufasha kurinda selile kwangirika kwa okiside, niyo mpamvu nyamukuru yo gusaza.

Iyo selile zihuye nibikorwa byubusa bikabije, reaction ya okiside irashobora kubaho, biganisha ku rupfu rutaragera. Gufata ibiryo bitameze neza, kunywa itabi, nibindi byangiza ibidukikije nko guhumana kwikirere nabyo byongera kwangiza okiside.Palmitoylethanolamide irashobora gukumira ibyo byangiza ikuraho radicals yubusa kandi bikagabanya ingaruka zose ziterwa numubiri.

Byongeye kandi, palmitoylethanolamide Ethanol yerekanwe ko ishobora kuzamura umusaruro wa kolagene nizindi poroteyine zuruhu zingenzi. Kubwibyo, irashobora kugabanya isura yiminkanyari nimirongo myiza, ikora nkurinda imbere muri selile.

Suzhou Myland Pharm & Nutrition Inc ni uruganda rwanditswe na FDA rutanga ifu nziza kandi nziza cyane ya Palmitoylethanolamide (PEA).

Muri Pharm ya Suzhou Myland twiyemeje gutanga ibicuruzwa byiza cyane kubiciro byiza. Ifu yacu ya Palmitoylethanolamide (PEA) irageragezwa cyane kugirango isukure nimbaraga, ikwemeza ko uzabona inyongera nziza-nziza ushobora kwizera. Waba ushaka gushyigikira ubuzima bwa selile, kongera imbaraga z'umubiri wawe, cyangwa kuzamura ubuzima muri rusange, ifu yacu ya Palmitoylethanolamide (PEA) niyo guhitamo neza.

Hamwe nuburambe bwimyaka 30 kandi itwarwa nubuhanga buhanitse hamwe nuburyo bunoze bwa R&D, Pharm ya Suzhou Myland Pharm yateje imbere ibicuruzwa bitandukanye byapiganiwe kandi ihinduka ubuzima bushya bwa siyanse yubuzima, synthèse progaramu na sosiyete ikora serivise.

Mubyongeyeho, Suzhou Myland Pharm nayo ikora FDA yemewe. Ibikoresho bya sosiyete R&D, ibikoresho byububiko, nibikoresho byisesengura nibigezweho kandi bikora byinshi, kandi birashobora gukora imiti kuva kuri miligarama kugeza kuri toni mubipimo, kandi ikubahiriza ibipimo bya ISO 9001 nibisobanuro byakozwe na GMP.