Ni iki ukeneye kumenya kuri palmitoylethanolamide (PEA)?

Palmitoylethanolamide (PEA) ni aside irike isanzwe ikurura abantu benshi kubera akamaro kayo ku buzima. Iyi mvange iboneka mu ngingo zitandukanye z'umubiri, kandi ubushakashatsi bwerekana ko palmitamideethanol (PEA) ishobora kugabanya ububyimbirwe, ikagabanya ububabare, kandi ishobora no guteza imbere ubuzima bwiza bw'amara no gutinda gusaza. Ishobora kugira inyungu zitandukanye ku buzima. Ibikubiye muri iyi nyandiko bizareba akamaro ka palmitoylethanolamide (PEA) ku buzima, uko ikora ku mubiri w'umuntu, n'uburyo bwo kubona palmitoylethanolamide (PEA) nziza cyane.

Palmitoylethanolamide (PEA) ni iki?

Palmitoylethanolamide (PEA) ni ikintu kimeze nk'ingirabuzimafatizo kizwiho kugira ubushobozi bwo kugabanya ububabare no kurwanya ububyimbirwe buhoraho. Uretse kuba umubiri ubikora, PEA iboneka mu biribwa bitandukanye birimo: foromaje, umuhondo w'igi, inyama, amata, ubunyobwa, soya lecithin.

Wari ubizi? Iyo umubiri uhuye n'ibintu bigutera stress, nko gukomereka cyangwa kubyimba, urugero rwa PEA rurahinduka kugira ngo rukomeze kugira ubuzima bwiza.

Palmitoylethanolamide igira izihe ngaruka ku mubiri w'umuntu?

Abahanga mu bya siyansi ntibarasobanukirwa neza uburyo palmitoylethanolamide ikora. Nyamara, twageze kure, tubikesha Porofeseri Rita Levi-Montalcini, wasobanuye muri rusange uburyo palmitoylethanolamide ikora. Kuva icyo gihe, yakomeje kwiga ingaruka za palmitoylethanolamide ku bubabare bw'imitsi n'ubwivumbure.

Palmitoylethanolamide ishobora kuzanira abantu inyungu enye z'ingenzi ku buzima:

●Kugabanya ingaruka z'ububyimbirwe.

●Gabanya gukora kwa mast cells (allergie).

● Kongera imbaraga mu mikorere y'urumogi rw'ibimera bikomoka ku bimera.

●Kora ibikoresho byihariye bya elegitoroniki mu mubiri.

Ni gute PEA igira ingaruka zo kurwanya ububyimbirwe no kugabanya ububabare?

Ibyiza bya PEA ku buzima birimo ingaruka ku turemangingo tw’umubiri tugenzura ububyimbirwe, cyane cyane mu bwonko. PEA ishobora gufasha kugabanya umusaruro w’ibintu bitera ububyimbirwe. Ariko, PEA ikora cyane cyane ku turemangingo, tugenzura imikorere itandukanye y’uturemangingo. Izi receptor zitwa PPAR. PEA n’ibindi bintu bifasha gukora PPAR bishobora kugabanya ububabare kandi bishobora no kongera imikorere y’umubiri binyuze mu gutwika ibinure, kugabanya triglycerides mu maraso, kongera cholesterol ya HDL mu maraso, kunoza uburyo isukari igenzurwa mu maraso, no gufasha kugabanya ibiro.

Ibyiza bya Palmitoylethanolamide

Bitewe n’ingaruka zayo zo kugabanya ububabare no kugabanya ububyimbirwe, ubushakashatsi bwerekana ko PEA ishobora gufasha mu ndwara zitandukanye ziterwa n’ububabare, nka fibromyalgia, sciatica, na osteoarthritis.

1. Kugabanya ububabare n'ingaruka z'ububyimbirwe

Ububabare budakira ni ikibazo gikomeye gihangayikishije abarwayi hirya no hino ku isi, kandi uko abaturage bagenda bakura, iki kibazo kizarushaho kuba gikomeye. Imwe mu nshingano za palmitoylethanolamide ni uko ishobora gufasha kugabanya ububabare n'ububyimbirwe. Palmitoylethanolamide ikorana na CB1 na CB2 receptors, ari byo bintu by'ingenzi bigize sisitemu y'uturemangingo tw'umubiri. Iyi sisitemu ishinzwe kubungabunga homeostasis cyangwa kuringaniza umubiri.

Iyo habayeho imvune cyangwa ububyimbirwe, umubiri urekura ibintu bya hemp byo mu bwoko bwa endogenous kugira ngo bifashe mu kugenzura uburyo ubudahangarwa bw'umubiri bwitwara. Palmitoylethanolamide ishobora gufasha kongera urugero rw'hemp yo mu bwoko bwa endogenous mu mubiri, bityo ikagabanya ububabare n'ububyimbirwe.

Byongeye kandi, palmitoylethanolamide ishobora kugabanya irekurwa ry’imiti itera ububabare no kugabanya ingaruka zose z’ububabare mu mitsi. Izi ngaruka zituma palmitoylethanolamide iba igikoresho gishobora gufasha mu kugenzura ububabare n’ingaruka z’ububabare. Ubushakashatsi bwerekana ko palmitoylethanolamide ishobora no kugira akamaro mu kuvura ububabare bwa sciatica na carpal tunnel syndrome.

2. Fibromyalgie

Ubushakashatsi butandukanye bwerekana ko PEA ishobora gufasha kugabanya ibimenyetso bya fibromyalgia, indwara idakira yo mu bwonko itera ububabare bukabije. Iyo ikoreshejwe nk'inyongera ku buvuzi gakondo, kuyinywa bigabanya ububabare kandi bikanoza ubuzima uko igihe kigenda gihita. Nk'uko ubushakashatsi bumwe bwabigaragaje, gufata PEA mu gihe cy'amezi atatu bigabanya cyane ububabare ku bantu barwaye fibromyalgia.

3. Kubabara umugongo

Ubushakashatsi bw’ibanze bwerekana ko PEA ishobora kugira akamaro mu kuvura ububabare bw’umugongo. Inyigo yo mu 2017 yerekanye ko PEA yagabanije ububabare ku barwayi bafite indwara yo kubagwa umugongo yananiwe.

Abantu barwaye sciatica, ububabare buhera mu mugongo wo hasi ugana hasi ku kaguru kamwe cyangwa yombi, bashobora no kuruhuka nyuma yo gufata PEA. Igerageza ryakozwe ku buryo butaziguye, ritagaragara ku mpande zombi, ryagenzuwe na placebo ryize ku ngaruka za PEA ku gipimo kinini n'icya placebo. Ububabare bwagabanutseho ibirenze 50% mu itsinda ryahawe dose nyinshi. Nubwo PEA ku gipimo gito itageze ku rugero rumwe rwo kugabanya ububabare nk'uko yahabwaga dose nyinshi, dose zombi zari zifite akamaro kanini kurusha placebo.

4. Osteoarthritis

PEA ishobora kuba ingirakamaro ku bantu barwaye osteoarthritis, indwara irangwa no kwangirika kw'ingingo n'amagufwa. Abitabiriye ubushakashatsi bwa PEA bagaragaje iterambere rikomeye mu manota ya Western Ontario na McMaster Universities Osteoarthritis Index (WOMAC) ugereranije n'itsinda rya placebo. WOMAC ni urutonde rw'ibibazo rwagenewe gusuzuma imiterere n'ibimenyetso (urugero: ububabare, gukomera, imikorere y'umubiri) ku barwayi ba osteoarthritis yo mu ivi no mu kibuno.

Ubundi bushakashatsi bwakorewe ku barwayi bafite ububabare bwa temporomandibular arthritis (TMJ) bujyanye na osteoarthritis bwagaragaje ko inyongera ya PEA yongereye ububabare cyane nyuma y'iminsi 14 ugereranije na ibuprofen. Itsinda ryahawe PEA mu minsi 14 ryagaragaje iterambere rikomeye mu gufungura umunwa cyane (igipimo cyo kugabanya ububabare) ugereranije n'itsinda rya ibuprofen.

5. Ububabare bw'imitsi

Inyigo z’ibanze n’ibizamini by’inyamaswa bigaragaza ko PEA ishobora gufasha ku bubabare bw’imitsi (buterwa no kwangirika kw’imitsi ijyana ubutumwa hagati y’ubwonko n’umugongo), cyane cyane ku bantu bafite indwara ya carpal tunnel syndrome, diyabete neuropathy, chimiotherapie Abantu bafite peripheral neuropathy, ububabare budakira bwo mu kibuno, n’ububabare bujyanye no gucika intege kw’imitsi na multiple sclerosis. Hakenewe izindi geragezwa zo kwa muganga kugira ngo hamenyekane akamaro ka PEA mu gukemura ububabare bw’imitsi.

6. Kugera mu zabukuru neza

Gutinza gusaza ni intego y'ingirakamaro ikurikiranwa n'abahanga benshi ku isi. Palmitoylethanolamide ifatwa nk'inyongeramusaruro irwanya gusaza ishobora gufasha kurinda uturemangingo kwangirika kwa ogisijeni, ari nayo mpamvu nyamukuru itera gusaza.

Iyo uturemangingo tugize uturemangingo duhura n’ibikorwa byinshi bya free radicals, oxidative reactions zishobora kubaho, bigatera urupfu rw’uturemangingo imburagihe. Kurya ibiryo bitameze neza, kunywa itabi, n’ibindi bintu bishobora kwangiza ibidukikije nk’umwuka uhumanya ikirere nabyo byongera kwangirika kwa oxidative. Palmitoylethanolamide ishobora gukumira uku kwangirika ikuraho free radicals no kugabanya ingaruka z’ububyimbirwe mu mubiri muri rusange.

Byongeye kandi, palmitoylethanolamide ethanol byagaragaye ko ishobora gutera imbaraga mu gukora kolajeni n'izindi poroteyine z'ingenzi ku ruhu. Kubwibyo, ishobora kugabanya iminkanyari n'imirongo mito, ikarinda uturemangingo.

Suzhou Myland Pharm & Nutrition Inc. ni uruganda rwemewe na FDA rutanga ifu ya Palmitoylethanolamide (PEA) nziza kandi isukuye cyane.

Muri Suzhou Myland Pharm twiyemeje gutanga ibicuruzwa byiza cyane ku giciro cyiza. Ifu yacu ya Palmitoylethanolamide (PEA) irageragezwa neza kugira ngo imenyekane ko ari nziza kandi ifite imbaraga, bityo ukaba ubona inyongeramusaruro nziza ushobora kwizera. Waba ushaka gufasha ubuzima bw'uturemangingo, kongera ubudahangarwa bw'umubiri wawe, cyangwa kongera ubuzima bwiza muri rusange, ifu yacu ya Palmitoylethanolamide (PEA) ni yo mahitamo meza.

Suzhou Myland Pharm ifite uburambe bw'imyaka 30 kandi iyobowe n'ikoranabuhanga rigezweho hamwe n'ingamba zo gukora ubushakashatsi n'iterambere zinoze cyane, yateje imbere ibicuruzwa bitandukanye kandi iba ikigo gishya gitanga serivisi z'inyongera ku buzima, gukora ibintu bitandukanye no gukora ibikoresho bitandukanye.

Byongeye kandi, Suzhou Myland Pharm ni uruganda rwanditswe na FDA. Imbuga z’ubushakashatsi n’iterambere by’iyi sosiyete, ibikoresho byayo byo gukora, n’ibikoresho byo gusesengura ni ibintu bigezweho kandi bifite imikorere myinshi, kandi bishobora gukora imiti kuva kuri miligarama kugeza kuri toni, kandi bikurikiza amahame ya ISO 9001 n’ibipimo bya GMP mu gukora.