Choline Alfoscerate ni iki kandi nigute ishobora gufasha ubwonko bwawe?

Nkibintu bya endogenous mumubiri wumuntu, L-α-glycerophosphocholine Irashobora kwinjira mumaraso yubwonko bwamaraso kandi ifite bioavailable cyane. Nintungamubiri zujuje ubuziranenge zingirakamaro kumubiri wumuntu. . ifite inyungu zishobora kugabanya amaganya, guhagarika umutima, no kongera imbaraga imitsi no kwihangana. "Ingaruka zintungamubiri za L-α-glycerophosphocholine zigaragarira cyane mubice 5.

Imwe ni ugutezimbere imikorere yubwonko. Umubare munini w'uturemangingo tw'ubwonko mu bwonko, niko imbaraga zazo zikomeye, nikohereza vuba ibimenyetso by'imitsi, ndetse n'imbaraga zo gutunganya ubwonko. L-α-glycerophosphocholine irashobora kunoza byimazeyo imikorere yubwonko yongerera imbaraga ingirabuzimafatizo nubushobozi bwo kwanduza ibimenyetso byimitsi. Mu rwego rwo kongera ubwonko bwa cholinergique, kwanduza ibimenyetso hagati ya selile nervice bishingiye ku kwanduza neurotransmitter, kandi acetylcholine nintumwa nyamukuru yimiti na neurotransmitter itanga ibitekerezo bikora kandi ikomeza guhuza ubwonko numubiri wose.

L-α-glycerophosphocholine irashobora kubora mo fosifate 3-glycerol na choline mu bwonko kandi niyo itanga neza cyane ya acetyloline. Irashobora kongera kwibuka no kunoza imitekerereze iteza imbere synthesis no kurekura acetylcholine mubwonko. Mu rwego rwo kongera ituze n’amazi ya selile, L-α-glycerophosphocholine irashobora guteza imbere synthesis ya fosifinositide, bityo bikazamura ituze n’amazi ya selile. Neuron ifite imiterere idahwitse irashobora kohereza amakuru neza. Kunoza imitekerereze yumubiri.

Iya kabiri ni imirire no kurinda imitsi. Ibintu bya Neurotrophique, ibintu bikura byimyanya myakura, birashobora kugenga itandukanyirizo ryingirabuzimafatizo no guteza imbere imikoranire mishya. L. Muri icyo gihe, L-α-glycerophosphocholine irashobora kandi guteza imbere imisemburo ya hormone yo gukura no gukomeza ubuzima bwumubiri byongera imisemburo ikura yumubiri.

Iya gatatu ni antioxydeant. Oxidation hamwe no gutwika nimpamvu nyamukuru zitera gusaza no gupfa kwingirangingo zubwonko. L. Kurekura ibintu bitera nka IL-6 birwanya uburibwe bwubwonko, bityo bigahindura cyane kugabanuka kwimikorere yubwenge no gukumira indwara niterambere ryindwara zifata ubwonko.

Ingaruka zingirakamaro zashyigikiwe ningaruka zamavuriro. Mu bushakashatsi "Ingaruka za L-α-glycerophosphocholine ku bijyanye no kutagira imyaka yo kwibuka", amasomo 4 yahawe umwanya, naho andi masomo 5 yatanzwe Nyuma yo gufata L-α-glycerophosphocholine (1200 mg / ku munsi) mu kanwa amezi 3 , Electrode 16 yakoreshejwe mu gufata amajwi yubwonko muminota 5 mugihe amasomo yari maso kandi aruhuka. Ibisubizo byerekanye ko ugereranije na placebo, L-alpha-glycerophosphocholine yongereye cyane igipimo cyubwonko bwihuta bwubwonko mugihe gifite imyumvire yo kugabanya umuvuduko mwinshi. Ni ukuvuga, irashobora kongera imbaraga zubwonko bwabantu bageze mu za bukuru kandi bigatinda gusaza kwumubiri.

Icya kane ni uguhuza amarangamutima. Dopamine irashobora gutuma abantu bumva bishimye, kandi serotonine na acide gamma-aminobutyric irashobora kugenga umubiri. L. irashobora kandi guteza imbere cyane endogenous Kurekura γ-aminobutyric acide mumyanya ndangagitsina ya corticale igabanya ubukana, bityo ikagira ingaruka zayo zo kurwanya depression, kugabanya amaganya no guhagarika umutima.

Icya gatanu nukuzamura imikorere ya siporo. Mugihe cy'imyitozo ngororamubiri, L-alpha-glycerophosphocholine nayo iteza imbere umubiri mu kongera imitsi no kunoza ibikorwa bya metabolike muri rusange byongera imisemburo ikura ikabije kandi ikabyara ingufu. Byongeye kandi, L-α-glycerophosphocholine irashobora kandi kwihutisha kwanduza neurotransmitter, kunoza imikorere y’imitsi iva mu mitsi, kongera ubwiyongere no kwihanganira imitsi ya skeletale, bityo bikongerera imbaraga umubiri imyitozo ngororamubiri, kurwanya umunaniro, no kugira uruhare runini mu mikurire yimitsi . Ingaruka.

None abantu bashobora gukura he intungamubiri hamwe ninyungu nyinshi zishoboka? Mubyukuri, L-α-glycerophosphocholine ikubiye mu biribwa byinshi nk'amagi, inkoko, n'umukororombya, ariko muri rusange ni bike. Dukurikije "Igitabo cya kabiri cy’ububiko rusange bw’ibiribwa muri Amerika muri rusange" cyashyizwe ahagaragara n’ishami ry’ubuhinzi muri Amerika, ibikubiye muri L-α-glycerophosphocholine mu biryo 630 byose hamwe mu byiciro 22 byerekanaga ko L-α-glycerophosphocholine kuri 100 garama y'ibiryo Ibiri muri glycerophosphocholine biri hagati ya mg 0 na 190. Kubwibyo, kugirango uhuze ibyifuzo byikura ryumubiri wumuntu, iterambere na metabolism, inyongera zinyongera zirashobora gukorwa muburyo bukwiye.

Sintezike yimiti nimwe muburyo nyamukuru bwo gukora L-α-glycerophosphocholine. Ukoresheje aside polifosifike, chorine ya choline, R-3-chloro-1,2-propanediol, hydroxide ya sodium namazi nkibikoresho fatizo, nyuma ya kondegene na esterification reaction, irahinduka amabara, umwanda ukurwaho, kwibanda, gutunganywa no gukama. L-α-glycerophosphocholine yakozwe nubundi buryo irashobora kongerwaho ibinyobwa bidasembuye, ibinyobwa bya siporo, ikawa, gummies, utubari tw’ingufu za oatmeal, nibindi, kandi birashobora kugira ingaruka zimirire muburyo bugamije guhuza ubuzima bwimirire itandukanye yabaguzi. bikenewe.

Muri Amerika, Ubuyapani, Kanada no mu bindi bihugu, L-α-glycerophosphocholine yakoreshejwe cyane mu biribwa. Ibicuruzwa bifitanye isano bikubiyemo inyongeramusaruro, ibinyobwa, gummies nibindi byiciro, kandi buri gicuruzwa gifite Imikorere isobanutse, dosiye isabwa hamwe nitsinda risabwa.

Suzhou Myland Pharm & Nutrition Inc.ni uruganda rwanditswe na FDA rutanga ifu ya Alpha GPC nziza kandi nziza.

Muri Pharm ya Suzhou Myland twiyemeje gutanga ibicuruzwa byiza cyane kubiciro byiza. Ifu yacu ya Alpha GPC irageragezwa cyane kugirango isukure nimbaraga, ikwemeza ko uzabona inyongera nziza-nziza ushobora kwizera. Waba ushaka gushyigikira ubuzima bwimikorere, kuzamura sisitemu yumubiri cyangwa kuzamura ubuzima muri rusange, ifu ya Alpha GPC niyo ihitamo neza.

Hamwe nuburambe bwimyaka 30 kandi itwarwa nubuhanga buhanitse hamwe nuburyo bunoze bwa R&D, Pharm ya Suzhou Myland Pharm yateje imbere ibicuruzwa bitandukanye byapiganiwe kandi ihinduka ubuzima bushya bwa siyanse yubuzima, synthèse progaramu na sosiyete ikora serivise.

Mubyongeyeho, Suzhou Myland Pharm nayo ikora FDA yemewe. Ibikoresho bya sosiyete R&D, ibikoresho byo kubyaza umusaruro, nibikoresho byisesengura nibigezweho kandi byinshi, kandi birashobora gukora imiti kuva kuri miligarama kugeza kuri toni mubipimo, kandi ikubahiriza ibipimo bya ISO 9001 nibisobanuro bya GMP.