Choline Alfoscerate ni iki kandi yafasha ite ubwonko bwawe?

Nk'ikintu cy'umwimerere mu mubiri w'umuntu, L-α-glycerophospholine ishobora kwinjira mu ruzitiro rw'amaraso n'ubwonko kandi ifite ubushobozi bwo kubaho bwinshi cyane. Ni intungamubiri nziza cyane kandi ifitiye akamaro umubiri w'umuntu. "Uruzitiro rw'amaraso n'ubwonko ni imiterere ikomeye, isa n'urukuta hagati y'imitsi y'ubwonko. L-α-glycerophosphocholine ishobora kwinjira mu ruzitiro rw'amaraso n'ubwonko byoroshye kandi ikagira uruhare mu kongera kwibuka, kunoza imitekerereze, kandi Ifite akamaro gashoboka mu kugabanya imihangayiko, gutuza, no kongera imbaraga z'imitsi no kwihangana." Ingaruka z'imirire za L-α-glycerophosphocholine zigaragarira ahanini mu bintu 5.

Kimwe muri byo ni ukunoza imikorere y'ubwonko. Uko uturemangingo tw'imitsi tuba twinshi mu bwonko, ni ko imbaraga zatwo zirushaho gukomera, ni ko twohereza vuba ibimenyetso by'imitsi, kandi ni ko imbaraga z'ubwonko zo gutunganya zirushaho kwiyongera. L-α-glycerophosphocholine ishobora kunoza imikorere y'ubwonko mu buryo bwuzuye binyuze mu kongera imbaraga z'uturemangingo tw'imitsi n'ubushobozi bwo kohereza ibimenyetso by'imitsi. Mu bijyanye no kongera uburyo bwo kohereza ibimenyetso mu bwonko bwa cholinergic, kohereza ibimenyetso hagati y'uturemangingo tw'imitsi bishingiye ku kohereza kwa neurotransmitters, kandi acetylcholine ni igikoresho cy'ingenzi cyo kohereza no kohereza neurotransmitter gituma umuntu atekereza neza kandi kigakomeza guhuza ubwonko n'umubiri wose.

L-α-glycerophosphocholine ishobora guhindurwamo phosphate ya 3-glycerol na choline mu bwonko kandi ni yo acetylcholine ikora neza cyane. Ishobora kongera kwibuka no kunoza imitekerereze binyuze mu guteza imbere imikorere no kurekura acetylcholine mu bwonko. Mu rwego rwo kongera ituze n'uburyo membranes z'uturemangingo zihamye, L-α-glycerophosphocholine ishobora guteza imbere imikorere ya phosphoinositide, bityo ikongera ituze n'uburyo membranes z'uturemangingo zihamye. Uturemangingo dufite imiterere ihamye dushobora kohereza amakuru neza. Kunoza ubushobozi bwo gutekereza bw'umubiri.

Icya kabiri ni imirire n'uburinzi bw'imitsi. Ibintu bitera uburwayi bw'imitsi, ibintu bitera uburwayi bw'imitsi, bishobora kugenzura ihinduka ry'uturemangingo tw'umubiri no guteza imbere ishingwa ry'imitsi mishya. L-α-glycerophosphocholine ishobora guteza imbere isohoka ry'ibintu bitandukanye bitera uburwayi bw'imitsi no gukora inzira z'ibimenyetso zijyanye no kubaho kw'uturemangingo, bityo ikagira ingaruka nziza ku mikorere y'ubwonko kandi ikanoza urwego rw'ubwenge bw'umubiri. Muri icyo gihe, L-α-glycerophosphocholine ishobora kandi guteza imbere isohoka ry'imisemburo itera uburwayi bw'imitsi no kubungabunga ubuzima bw'umubiri binyuze mu kongera urugero rw'imisemburo itera uburwayi bw'imitsi.

Icya gatatu ni antioxydant. Oxidation no kubyimba ni byo bintu by'ingenzi bituma uturemangingo tw'ubwonko dusaza kandi tugapfa. L-α-glycerophosphocholine ishobora gukuraho uturemangingo tw’ubuntu mu mubiri, ikarwanya stress ya oxidative, kandi ishobora no kugabanya NF-κB, tumor necrosis factor TNF-α, na interleukins. Irekurwa ry’ibintu bitera ubushyuhe nka IL-6 rirwanya ubushyuhe mu bwonko, bityo bigasubiza inyuma cyane igabanuka ry’imikorere y’ubwonko no gukumira indwara zitera ubushyuhe mu bwonko.

Ingaruka zifatika zashimangiwe n’ingaruka z’ubuvuzi. Mu bushakashatsi bwakozwe ku "Ingaruka za L-α-glycerophosphocholine ku kugabanuka k’ubwonko bushingiye ku gusaza", abantu 4 bahawe placebo, abandi bantu 5 bahabwa. Nyuma yo gufata L-α-glycerophosphocholine (1200 mg / ku munsi) mu kanwa mu gihe cy’amezi 3, electrode 16 zakoreshejwe mu kwandika imiraba y’ubwonko mu gihe cy’iminota 5 mu gihe abantu bari maso kandi baruhutse. Ibisubizo byagaragaje ko ugereranije na placebo, L-alpha-glycerophosphocholine yongereye cyane igipimo cy’imiraba y’ubwonko yihuta mu gihe ifite ubushake bwo kugabanya inshuro zigenda buhoro. Ni ukuvuga ko ishobora kongera imbaraga z’ubwonko bw’abantu bari mu kigero cyo hagati no gutinda gusaza kw’umubiri.

Icya kane ni ukugenzura amarangamutima. Dopamine ishobora gutuma abantu bumva bishimye, naho serotonin na aside gamma-aminobutyric bishobora kugenzura ibyiyumvo by'umubiri. L-α-glycerophosphocholine ishobora guteza imbere irekurwa rya dopamine, kongera uburyo dopamine ikora, kunoza uburyo dopamine itwara mu bwonko, no kongera urugero rwa serotonin muri striatum na prefrontal cortex; ishobora kandi guteza imbere cyane imikorere y'umubiri. Irekurwa rya aside γ-aminobutyric mu ngingo z'igitsina rigabanya ububabare, bityo rikagira ingaruka zo kurwanya kwiheba, kugabanya imihangayiko no gutuza amarangamutima.

Icya gatanu ni ukunoza imikorere ya siporo. Mu gihe cy'imyitozo ngororamubiri, L-alpha-glycerophosphocholine inanoza imiterere y'umubiri binyuze mu kongera imitsi no kunoza imikorere y'imikorere y'umubiri muri rusange binyuze mu kongera imisemburo ikura neza n'umusaruro w'imbaraga. Byongeye kandi, L-α-glycerophosphocholine ishobora kandi kwihutisha ihererekanya ry'imitsi mu bwonko, kunoza imikorere y'imitsi yo mu bwonko, kongera ubushobozi bwo gufunga no kwihangana kw'imitsi yo mu bwonko, bityo yongera imbaraga z'imyitozo ngororamubiri, kurwanya umunaniro, no kugira ingaruka nziza ku mikurire y'imitsi.

None se abantu bashobora kubona he iyi ntungamubiri ifite inyungu nyinshi? Mu by’ukuri, L-α-glycerophosphocholine iboneka mu biribwa byinshi nk'amagi, inkoko, na rainbow trout, ariko muri rusange ibikubiye muri yo ni bike. Dukurikije "Igitabo cya kabiri cya US General Food Choline Content Database" cyasohotse na Minisiteri y'Ubuhinzi ya Leta Zunze Ubumwe za Amerika, ibikubiye muri L-α-glycerophosphocholine mu biribwa 630 mu byiciro 22 byagaragaje ko L-α-glycerophosphocholine kuri garama 100 z'ibiribwa Ibikubiye muri glycerophosphocholine biri hagati ya 0 na 190 mg. Kubwibyo, kugira ngo habeho ibyifuzo by'imikurire y'umubiri w'umuntu, iterambere rye n'imikorere y'umubiri, hashobora gukorwa inyongeramusaruro zikwiye.

Gutunganya imiti ni bumwe mu buryo bw'ingenzi bwa L-α-glycerophosphocholine. Hakoreshejwe aside polyphosphoric, choline chloride, R-3-chloro-1,2-propanediol, sodium hydroxide n'amazi nk'ibikoresho fatizo, nyuma yo gushonga no gusya, birahinduka ibara, umwanda ukurwaho, bigashyirwamo imbaraga nyinshi, bigatunganywa kandi byumye. L-α-glycerophosphocholine ikorwa n'izindi nzira ishobora kongerwa ku binyobwa bidasembuye, ibinyobwa bya siporo, ikawa, gummies, oatmeal energy bar, nibindi, kandi ishobora kugira ingaruka nziza ku mirire mu buryo bugamije guhaza ubuzima butandukanye bw'imirire bw'abaguzi.

Muri Leta Zunze Ubumwe za Amerika, mu Buyapani, muri Kanada no mu bindi bihugu, L-α-glycerophosphocholine yakoreshejwe cyane mu biribwa. Ibikoresho bifitanye isano bikubiyemo inyongeramusaruro, ibinyobwa, gummy n'ibindi byiciro, kandi buri gicuruzwa gifite imikorere isobanutse, ingano isabwa n'amatsinda asabwa.

Suzhou Myland Pharm & Nutrition Inc. ni uruganda rwemewe na FDA rutanga ifu ya Alpha GPC nziza kandi isukuye cyane.

Muri Suzhou Myland Pharm twiyemeje gutanga ibicuruzwa byiza cyane ku giciro cyiza. Ifu yacu ya Alpha GPC irageragezwa cyane kugira ngo imenyekane ko ari nziza kandi ifite imbaraga, bityo ukaba wabona inyongeramusaruro nziza ushobora kwizera. Waba ushaka gufasha ubuzima bw'uturemangingo, kongera ubudahangarwa bw'umubiri wawe cyangwa kongera ubuzima bwiza muri rusange, ifu yacu ya Alpha GPC ni yo mahitamo meza.

Suzhou Myland Pharm ifite uburambe bw'imyaka 30 kandi iyobowe n'ikoranabuhanga rigezweho hamwe n'ingamba zo gukora ubushakashatsi n'iterambere zinoze cyane, yateje imbere ibicuruzwa bitandukanye kandi iba ikigo gishya gitanga serivisi z'inyongera ku buzima, gukora ibintu bitandukanye no gukora ibikoresho bitandukanye.

Byongeye kandi, Suzhou Myland Pharm ni uruganda rwanditswe na FDA. Imbuga z’ubushakashatsi n’iterambere by’iyi sosiyete, ibikoresho byayo byo gukora, n’ibikoresho byo gusesengura ni ibintu bigezweho kandi bifite imikorere myinshi, kandi bishobora gukora imiti kuva kuri miligarama kugeza kuri toni, kandi bikurikiza amahame ya ISO 9001 n’ibipimo bya GMP mu gukora.