Salidroside ni iki kandi nigute ishobora kugufasha?

Salidroside izwi kandi nka (4-hydroxy-phenyl) -β-D-glucopyranoside, izwi kandi nka salidroside na rhodiola. Irashobora gukurwa muri Rhodiola rose cyangwa ikomatanya. Salidroside ni antioxydants isanzwe irinda ingirangingo zogosha ROS no kubuza apoptose selile.

Rhodiola rose ni igihingwa cyatsi kimera cyane gikura mubice bifite ubukonje bwinshi, bwumutse, anoxia, imirasire ikomeye ya ultraviolet, hamwe nubushyuhe butandukanye hagati yumunsi nijoro ku butumburuke bwa metero 1.600 kugeza 4000. Ifite imbaraga zikomeye zo kurwanya ibidukikije no kubaho.

Salidroside - Antioxydeant

Salidroside ni antioxydants isanzwe ishobora gukuramo ubwoko bwa ogisijeni ikora (ROS), ikabuza apoptose, kandi ikarinda ingirabuzimafatizo. Irashobora kunoza ubushobozi bwokwirinda antioxydeant yuruhu mugukoresha sisitemu yo mu bwoko bwa antioxydeant ya antioxydeant, nka superoxide dismutase (SOD), glutathione peroxidase (GSH-Px), nibindi.

Indwara ya calcium irenze urugero ni imwe mu mpamvu nyamukuru zitera apoptose ya neuronal. Rhodiola rosea ikuramo na salidroside irashobora kugabanya kwiyongera kurwego rwa calcium yubusa ya calcium iterwa na stress ya okiside kandi ikarinda selile cortique yabantu glutamate. na hydrogen peroxide iterwa na apoptose. Salidroside irashobora guhagarika lipopolysaccharide iterwa na microglial activation, ikabuza NTA musaruro, ikabuza ibikorwa bya nitric okiside synthase (iNOS), kandi bikagabanya TNF-α na IL-1β. Urwego rwa IL-6.

Salidroside ibuza okiside ya NADPH 2 / ROS / mitogen-ikora protein kinase (MAPK) hamwe nigisubizo cyo kwiteza imbere no kwangiza ADN 1 (REDD1) / inyamaswa z’inyamabere za rapamycin (mTOR) / p70 ribosome Poroteyine S6 kinase yerekana inzira ikora AMP iterwa na AMP protein kinase / gucecekesha amakuru agenga 1, RAS homologous gene mumuryango A / MAPK na PI3K / Akt yerekana inzira.

Inyungu za Salidroside

1. Ingaruka yuburyo bubiri: Rhodiola rosea ikusanya ibintu byose byiza mumubiri kandi ifite uburyo bubiri bwo kugenzura ibyuzuye no kugabanya ibirenze. Mugutunganya imikorere ya sisitemu ya nervice, sisitemu ya endocrine na sisitemu ya metabolike, isukari yamaraso, lipide yamaraso, umuvuduko wamaraso hamwe nimikorere yumutima nimiyoboro yubwonko nubwonko bishobora gusubira kurwego rusanzwe.

2.Gutegeka neza sisitemu yimitsi: kurandura neza impagarara zabantu, kuringaniza sisitemu yo hagati, kunoza ibitotsi no kurakara, kwishima cyangwa kwiheba; kunoza ibitekerezo no kongera kwibuka. Kuvugurura ubwonko, kugabanya igipimo cyamakosa, kunoza akazi no gukora neza, kandi wirinde indwara ya Alzheimer.

3. Kurwanya umunaniro: Rhodiola rosea ifite ingaruka z'umutima, zishobora kongera igihe cyibikorwa bisanzwe byubwonko numubiri kandi bikongerera ubushobozi imitwaro yubwonko nubwonko bwumubiri. Ifite ingaruka zikomeye mukurinda no kuvura syndrome yumunaniro no gukomeza imbaraga nubuzima igihe kirekire.

4. Ifite ingaruka nziza cyane zo gusubiza mu buzima busanzwe abafite intege nke kumubiri nyuma yuburwayi.

5. .

6. Ingaruka kumitsi yoroshye yumuntu: Asima iterwa no kunanuka kwimitsi. Rhodiola rose irashobora kugabanya cyane imitsi yimitsi kandi ikagenga imitsi igenda neza. Ifite ingaruka zigaragara kuri asima, bronchite, flegm, impatwe, nibindi

7. Ingaruka kuri rubagimpande ya rubagimpande: Arthrite iterwa nibibi bitatu byumuyaga, ubukonje, nubushuhe. Umubare munini wibigereranyo byamavuriro wagaragaje ko Rhodiola rose ishobora kwirukana umuyaga, kurwanya ubukonje, no gukuraho ububabare. Ifite cyane cyane ingaruka zigaragara kubyimba. Ingaruka zo kubyimba no kubuza.

8. Kongera metabolisme selile hamwe na synthesis kandi utezimbere ubuzima bwimikorere. Mubyongeyeho, ifite kandi ubwiza n'ingaruka zo kwita ku ruhu.

Salidroside & Umwanya wo Kwitaho Uruhu

Mu rwego rwo kwita ku ruhu, salidroside irashobora kurwanya kwangirika kwa ultraviolet no gukuraho radicals yubusa ikorwa na mitochondria. Ingaruka za antioxydeant na anti-inflammatory zirashobora kunoza imiterere yuruhu, kugabanya iminkanyari, no gutuma uruhu rusa nkumuto.

Rhodiola rose irashobora kugabanya ibikorwa bya fosifata ya acide nibicuruzwa byanyuma byangirika bya lipide peroxide (LPO) mukongera ibikorwa byimisemburo ifitanye isano na antioxydeant (SOD superoxide dismutase, GSH-Px glutathione peroxidase na CAT) nibirimo MDA, bityo bikazamura ubushobozi bwumubiri. gusibanganya radicals yubuntu, kugabanya urugero rwa peroxidisation ya biofilm, no kurinda ingirabuzimafatizo hamwe nuduce twumubiri kwangirika kwubusa.

Irinde gufotora uruhu

Salidroside irashobora kugabanya iyangirika rya matrice idasanzwe nka kolagen kandi igatera imikurire ya fibroblast, bityo bikazamura ubworoherane bwuruhu, gutinda kubaho kwinkari zuruhu, no kugera kumigambi yo kurwanya ifoto.

Kwera

Salidroside irashobora kugabanya synthesis ya melanin muguhagarika ibikorwa bya tyrosinase. Tyrosinase ni enzyme yingenzi ya synthesis ya melanin. Salidroside irashobora guhuza tyrosinase no kugabanya ibikorwa byayo, bityo bikagabanya umusaruro wa melanin.

Salidroside irashobora kandi kubuza synthesis ya melanin muguhuza inzira yerekana ibimenyetso muri melanocytes, nka MITF yerekana inzira. MITF ni ikintu cyingenzi cyo kwandukura muri melanocytes, igenga imvugo ya melanin synthesis ifitanye isano na enzymes nka tyrosinase. Salidroside irashobora kugabanya imvugo ya MITF, bityo igabanya synthesis ya melanin.

Kurwanya inflammatory

Salidroside irashobora kugabanya igisubizo cyatewe nimirasire ya ultraviolet, gusana ingirangingo zuruhu zangiritse, no guteza imbere uruhu no gusana.

Imiterere yumusaruro wa salidroside

1) Ahanini gushingira ku gukuramo ibimera

Rhodiola rosea nibikoresho fatizo bya salidroside. Nkubwoko bwibimera bimera, Rhodiola rose ikura cyane mubice bifite ubukonje bwinshi, anoxia, akuma nubushyuhe butandukanye hagati yumunsi nijoro ku butumburuke bwa metero 1600-4000. Ni kimwe mu bimera byo mu gasozi. Ubushinwa ni kamwe mu turere tw’ibanze twa Rhodiola roza ku isi, ariko ingeso zo kubaho za Rhodiola roza zirihariye. Ntabwo bigoye guhinga gusa, ariko umusaruro wubwoko bwishyamba ni muto cyane. Kugeza ubu, icyuho gisabwa buri mwaka kuri Rhodiola rose ni hejuru ya toni 2200.

2) Synthesis ya chimique na fermentation ya biologiya

Bitewe nibirimo bike hamwe nigiciro kinini cyumusaruro mubihingwa, usibye uburyo bwo kuvoma bisanzwe, uburyo bwo gukora salidroside burimo nuburyo bwo guhuza imiti, uburyo bwo gusembura ibinyabuzima, nibindi. Muri byo, uko ikoranabuhanga rikomeje gukura, fermentation yibinyabuzima yabaye inzira nyamukuru inzira yikoranabuhanga kubushakashatsi niterambere no gutanga umusaruro wa salidroside. Kugeza ubu, Suzhou Mailun yageze ku bushakashatsi n’iterambere kandi yageze ku nganda.

Imirasire nigice kidashobora kwirindwa mubuzima bwacu bwa buri munsi kandi ikoreshwa kenshi mugupima no kuvura. Ariko, ibyangiritse biterwa nimirasire yumubiri ningirabuzimafatizo byabantu ntibishobora kwirengagizwa. Kubwibyo, kubona ibikoresho bikora neza, bifite ubumara buke cyangwa bidafite ubumara bwangiza imirasire yamye nubushakashatsi.

Suzhou Myland Nutraceuticals Inc. ni uruganda rwanditswe na FDA rutanga ifu ya Salidroside nziza kandi nziza.

Kuri Suzhou Myland twiyemeje gutanga ibicuruzwa byiza cyane kubiciro byiza. Ifu ya Salidroside irageragezwa cyane kugirango isukure nimbaraga, ikwemeza ko uzabona inyongeramusaruro nziza ushobora kwizera. Waba ushaka gushyigikira ubuzima bwimikorere, kuzamura sisitemu yumubiri cyangwa kuzamura ubuzima muri rusange, ifu ya Salidroside niyo ihitamo neza.

Hamwe nuburambe bwimyaka 30 kandi itwarwa nubuhanga buhanitse hamwe nuburyo bunoze bwa R&D, Suzhou Myland yateje imbere ibicuruzwa bitandukanye byapiganwa kandi ihinduka ubumenyi bushya bwa siyanse yubuzima, synthesis gakondo hamwe nisosiyete ikora serivise.

Mubyongeyeho, Suzhou Myland nayo ikora FDA yemewe. Ibikoresho bya sosiyete R&D, ibikoresho byo kubyaza umusaruro, nibikoresho byisesengura nibigezweho kandi byinshi, kandi birashobora gukora imiti kuva kuri miligarama kugeza kuri toni mubipimo, kandi ikubahiriza ibipimo bya ISO 9001 nibisobanuro bya GMP.