Salidroside ni iki kandi yagufasha ite?

Salidroside izwi kandi nka (4-hydroxy-phenyl)-β-D-glucopyranoside, izwi kandi nka salidroside na rhodiola extract. Ishobora gukurwa muri Rhodiola rosea cyangwa igakoranywe ubuhanga. Salidroside ni antioxydant karemano irinda uturemangingo tw'imitsi binyuze mu gukuraho ROS no gukumira apoptosis y'uturemangingo.

Rhodiola rosea ni ikimera cy’ibyatsi kiramba gikurira cyane cyane mu turere dufite ubukonje bwinshi, ubwumye, anoxia, imirasire ikomeye ya ultraviolet, n’itandukaniro rikomeye ry’ubushyuhe hagati y’amanywa na nijoro ku butumburuke bwa metero 1.600 kugeza 4.000. Gifite ubushobozi bwo guhangana n’ibidukikije kandi gifite imbaraga nyinshi.

Salidroside--Antioxydant

Salidroside ni antioxydant karemano ishobora gukuraho ubwoko bwa ogisijeni (ROS), ikabuza apoptosis, kandi ikarinda uturemangingo tw’imitsi. Ishobora kongera ubushobozi bwo kurinda antioxydant y’uruhu binyuze mu gukora sisitemu za antioxydant mu ngirabuzimafatizo, nka superoxide dismutase (SOD), glutathione peroxidase (GSH-Px), nibindi.

Kurenza urugero rwa kalisiyumu mu turemangingo ni imwe mu mpamvu zikomeye zitera apoptosis y’imitsi y’ubwonko. Isosi ya Rhodiola rosea na salidroside bishobora kugabanya ubwiyongere bw’urugero rwa kalisiyumu yigenga mu turemangingo iterwa n’umuvuduko wa oxidative no kurinda uturemangingo tw’umubiri w’umuntu glutamate. Na apoptosis iterwa na hydrogen peroxide. Salidroside ishobora kubuza gukora kwa microglial iterwa na lipopolysaccharide, ikabuza ikorwa rya NO, ikabuza imikorere ya nitric oxide synthase (iNOS), kandi ikagabanya urugero rwa TNF-α na IL-1β., IL-6.

Salidroside ibuza NADPH oxidase 2/ROS/mitogen-activated protein kinase (MAPK) hamwe n’umugenzuzi w’iterambere n’iyangirika rya ADN 1 (REDD1)/intego ya mammalian ya rapamycin (mTOR)/p70 ribosome. Inzira yo gutanga ibimenyetso bya poroteyine S6 kinase ikora ku muyobozi wa poroteyine kinase/amakuru adacecetse 1, RAS homologous gene family member A/MAPK na PI3K/Akt signaling pathways.

Ibyiza bya Salidroside

1. Ingaruka zo kugenzura mu buryo bubiri: Rhodiola rosea ikora ibintu byose byiza mu mubiri kandi ikagira ingaruka zo kugenzura mu buryo bubiri zo gukosora ibitagenda neza no kugabanya ibirenze urugero. Mu kugenzura imikorere y'imitsi, imikorere y'imisemburo n'imikorere y'imisemburo, isukari mu maraso, umuvuduko w'amaraso n'imikorere y'umutima n'imitsi yo mu bwonko bishobora kugaruka ku rwego rusanzwe.

2. Kugenzura neza uturemangingo tw’imitsi: bikuraho neza umuvuduko w’abantu, bihuza uturemangingo tw’imitsi two hagati, bikongera gusinzira no kurakara, gushimishwa cyangwa kwiheba; bikongera ubushobozi bwo kwita ku bintu no kongera kwibuka. Bitera imbaraga ubwonko, bigabanya amakosa, bikongera ubushobozi bwo gukora no kwiga, kandi bikumire indwara ya Alzheimer.

3. Kurwanya umunaniro: Rhodiola rosea ifite ingaruka zo kuvura umutima, ishobora kongera igihe cy'imirimo isanzwe y'ubwonko n'umubiri ndetse no kongera ubushobozi bw'imitsi n'imitsi y'umubiri. Igira ingaruka zikomeye mu gukumira no kuvura indwara y'umunaniro no kugumana imbaraga n'imbaraga nyinshi igihe kirekire.

4. Kurwanya imirasire no kurwanya ikibyimba: Salidroside ishobora kongera neza igipimo cy’impinduka za lymphocytes T n’imikorere ya phagocytes, kongera ubudahangarwa bw’umubiri, kubuza gukura kwa kanseri, kongera uturemangingo tw’amaraso twera, kurwanya imirasire ya microwave, no kuvura abarwayi ba kanseri nyuma yo kuvurwa hakoreshejwe imirasire n’ibindi. Ifite akamaro keza cyane ko kuvura abananiwe nyuma yo kurwara.

5. Kurwanya hypoxia: Rhodiola rosea ishobora kugabanya umuvuduko w’umubiri wo gukoresha ogisijeni muri rusange, ikongera ubushobozi bw’ubwonko bwo kwihanganira hypoxia, kandi icyarimwe yongera ubushobozi bw’amaraso bwo gutwara ogisijeni, yongera ubudahangarwa bw’umubiri ku ndwara, kandi igasubiza vuba ingingo zirwaye.

6. Ingaruka ku mitsi yoroshye y'umuntu: Asima iterwa no kubabara kw'imitsi. Rhodiola rosea ishobora kugabanya cyane kubabara kw'imitsi no kugenzura imitsi yoroshye y'amara. Igira ingaruka zigaragara kuri asima, bronchitis, phlegm, impatwe, n'ibindi.

7. Ingaruka ku ndwara ya rubagimpande: Indwara ya rubagimpande iterwa n'ibibi bitatu by'umuyaga, ubukonje n'ubushuhe. Igerageza ryinshi ryagaragaje ko Rhodiola rosea ishobora kwirukana umuyaga, kurwanya ubukonje, no gukuraho ububabare. By'umwihariko igira ingaruka zigaragara ku kubyimba kw'ingingo. Kubyimba no gukumira indwara.

8. Kurwanya gusaza: Rhodiola rosea ishobora gutinza gusaza kw'uturemangingo, kongera imikorere ya SOD mu mubiri, no kubuza ikorwa rya lipofuscin mu turemangingo n'ubwoko bwa ogisijeni bukora neza. Yongera imikorere y'uturemangingo no gukora neza, inanoza ubuzima bw'uturemangingo. Byongeye kandi, ifite ubwiza n'ingaruka nziza ku ruhu.

Salidroside n'Ishami ryita ku Ruhu

Mu rwego rwo kwita ku ruhu, salidroside ishobora kurwanya kwangirika kwa ultraviolet no gukuraho uturemangingo tw’ubudahangarwa twakozwe na mitochondria. Ingaruka zayo zo kurwanya uburozi n’ubushyuhe zishobora kunoza imiterere y’uruhu, kugabanya iminkanyari, no gutuma uruhu rusa n’urukiri rukiri rushya.

Rhodiola rosea ishobora kugabanya imikorere ya aside phosphatase n'ibikomoka ku ibora rya nyuma rya lipid peroxide (LPO) binyuze mu kongera imikorere ya enzymes zifitanye isano na antioxydants (SOD superoxide dismutase, GSH-Px glutathione peroxidase na CAT) hamwe n'ingano ya MDA, bityo bikongera ubushobozi bw'umubiri bwo gukuraho radicals free, bigabanya urwego rwa peroxidation ya biofilms, kandi bikarinda uturemangingo n'ingingo z'umubiri kwangirika kwa radicals free.

Irinde gufata amashusho y'uruhu

Salidroside ishobora kugabanya kwangirika kwa matrix yo hanze y'umubiri nka kolajeni no guteza imbere ukwiyongera kwa fibroblast, bityo ikarushaho gukomera k'uruhu, igatinza iminkanyari y'uruhu, kandi ikagera ku ntego yo kurwanya fotoaging.

Kweza

Salidroside ishobora kugabanya ikorwa rya melanin ibuza imikorere ya tyrosinase. Tyrosinase ni enzyme y'ingenzi mu ikorwa rya melanin. Salidroside ishobora gufatana na tyrosinase ikagabanya imikorere yayo, bityo ikagabanya ikorwa rya melanin.

Salidroside ishobora kandi kubuza imikorere ya melanin igenzura inzira zo gutanga ibimenyetso muri melanocytes, nk'inzira yo gutanga ibimenyetso muri MITF. MITF ni ikintu cy'ingenzi mu kwandika melanocytes, kigenzura imikorere ya enzymes zijyanye na melanin nka tyrosinase. Salidroside ishobora kugabanya imikorere ya MITF, bityo ikagabanya imikorere ya melanin.

Irwanya ububyimbirwe

Salidroside ishobora kugabanya ingaruka z'ububyimbirwe buterwa n'imirasire ya ultraviolet, igasana uturemangingo tw'uruhu twangiritse, kandi igatuma uruhu rusubirana kandi rugasanwa.

Uko umusaruro wa salidroside uhagaze ubu

1) Bishingira ahanini ku gukura ibimera

Rhodiola rosea ni umwimerere wa salidroside. Nk'ubwoko bw'igihingwa cy'ibyatsi bihoraho, Rhodiola rosea ikura cyane cyane mu turere dufite ubukonje bwinshi, anoxia, ubwumye n'ubushyuhe bwinshi hagati y'amanywa na nijoro ku butumburuke bwa metero 1600-4000. Ni kimwe mu bimera byo mu gasozi. Ubushinwa ni kimwe mu bice by'ingenzi byera Rhodiola rosea ku isi, ariko imibereho ya Rhodiola rosea ni yihariye cyane. Ntabwo bigoye kuyihinga mu buryo bw'ubukorikori gusa, ahubwo n'umusaruro w'ubwoko bw'ibimera byo mu gasozi ni muto cyane. Kuri ubu, icyuho cy'ubukene bwa Rhodiola rosea buri mwaka ni toni 2.200.

2) Gutunganya imiti no kuyitunganya mu buryo bw'ibinyabuzima

Bitewe n'uko ibimera bifite ingano nto n'igiciro kinini cyo gukora, uretse uburyo bwo gukuramo ibinyabutabire mu buryo bw'umwimerere, uburyo bwo gukora salidroside burimo kandi uburyo bwo gukora imiti, uburyo bwo gukora fermentation mu buryo bw'ibinyabuzima, n'ibindi. Muri byo, uko ikoranabuhanga rikomeza gukura, fermentation mu buryo bw'ibinyabuzima yabaye inzira y'ikoranabuhanga ikoreshwa mu bushakashatsi no guteza imbere no gukora salidroside. Kuri ubu, Suzhou Mailun yageze ku musaruro w'ubushakashatsi n'iterambere kandi yageze ku nganda.

Imirasire ni igice cy’ubuzima bwacu bwa buri munsi kidasubirwaho kandi gikunze gukoreshwa mu gusuzuma no kuvura indwara. Ariko, ibyangiritse biterwa n’imirasire ku ngingo n’uturemangingo tw’abantu ntibishobora kwirengagizwa. Kubwibyo, gushaka imiti irinda imirasire neza, ifite uburozi buke cyangwa idafite uburozi byagiye biba ingenzi cyane mu bushakashatsi.

Suzhou Myland Nutraceuticals Inc. ni uruganda rwemewe na FDA rutanga ifu ya Salidroside nziza kandi isukuye cyane.

Muri Suzhou Myland twiyemeje gutanga ibicuruzwa byiza cyane ku giciro cyiza. Ifu yacu ya Salidroside irageragezwa neza kugira ngo imenyekane ko ari nziza kandi ifite imbaraga, bityo ukaba wabona inyongeramusaruro nziza ushobora kwizera. Waba ushaka gufasha ubuzima bw'uturemangingo, kongera ubudahangarwa bw'umubiri wawe cyangwa kongera ubuzima bwiza muri rusange, ifu yacu ya Salidroside ni yo mahitamo meza.

Suzhou Myland ifite uburambe bw'imyaka 30 kandi iyobowe n'ikoranabuhanga rigezweho n'ingamba zo gukora ubushakashatsi n'iterambere zinoze cyane, yateje imbere ibicuruzwa bitandukanye bihiganwa kandi iba ikigo gishya gitanga serivisi z'inyongera ku buzima, gukora ibintu bitandukanye no gukora ibikoresho bitandukanye.

Byongeye kandi, Suzhou Myland ni uruganda rwanditswe na FDA. Imbuga z’ubushakashatsi n’iterambere by’iyi sosiyete, ibikoresho byayo byo gukora, n’ibikoresho byo gusesengura ni ibintu bigezweho kandi bifite imikorere myinshi, kandi bishobora gukora imiti kuva kuri miligarama kugeza kuri toni, kandi bikurikiza amahame ya ISO 9001 n’ibipimo bya GMP mu gukora.