Ibyo ukeneye kumenya bijyanye no gusaza nuburyo ki ushobora gufata kugirango ubitindeho

Mugihe abantu basaza, benshi barimo gushakisha uburyo bwo kugabanya umuvuduko no gukomeza isura yubusore nubuzima. Hariho ingamba zitandukanye nubuhanga bushobora gukoreshwa mu gufasha gutinda gusaza no guteza imbere ubuzima rusange n'imibereho myiza.

Ubushakashatsi buheruka kwerekana bwerekana ko gusaza bitabaho buhoro buhoro, ahubwo binatangira mugihe runaka hagati yimyaka 44 na 60.

Guhera mu myaka ya za 40, lipid na alcool metabolisme ihinduka, mugihe imikorere yimpyiko yawe, metabolisme ya karubone, hamwe nubudahangarwa bw'umubiri itangira kugabanuka nko mu myaka 60. Abashakashatsi babonye kandi impinduka zikomeye ziterwa nuruhu, imitsi n'indwara z'umutima hagati yimyaka 40 na 60. kera.

Ubushakashatsi bwarimo Abanyakaliforniya 108 gusa bafite imyaka 25 kugeza 75, kandi harakenewe ubushakashatsi bwinshi kugirango hemezwe ibyagaragaye. Nyamara, ubu bushakashatsi bushobora kuganisha ku bizamini bishya byo gusuzuma no gufata ingamba zo gukumira indwara ziterwa no gusaza.

Kuramba ntibisobanura byanze bikunze ubuzima bwiza cyangwa bukora. Nk’uko byatangajwe n'umwanditsi mukuru w’ubwo bushakashatsi, Dr. Michael Snyder, umuyobozi w'ikigo gishinzwe ubuvuzi rusange n’ubuvuzi bwihariye muri kaminuza ya Stanford, ku bantu benshi, impuzandengo yabo "ubuzima bwabo" - igihe bamara mu buzima bwiza - ni kirekire kuruta igihe cyo kubaho kwabo ni gito Imyaka 11-15.

Ubuzima bwo hagati ni ingenzi mu gusaza neza

Ubushakashatsi bwibanze bwerekanye ko ubuzima bwawe mubuzima bwo hagati (ubusanzwe hagati yimyaka 40 na 65) bugira uruhare runini mubuzima bwawe nyuma mubuzima. Ubushakashatsi bwakozwe mu mwaka wa 2018 mu kinyamakuru Imirire bwahujije ibintu byihariye byo kubaho mu buzima bwo hagati, nk'uburemere buzira umuze, gukora cyane ku mubiri, kurya indyo nziza no kutanywa itabi, kugira ubuzima bwiza mu gihe cyo gusaza. 2

Raporo yasohotse mu kinyamakuru 2020 yerekanaga kandi ko igihe cyo hagati ari igihe gikomeye cy’ubuzima bw’ubwonko. Raporo ivuga ko kugenzura umuvuduko w'amaraso no kuguma mu mibereho, mu bwenge no ku mubiri muri iki gihe cy'ubuzima bishobora gufasha kugabanya ibyago byo guta umutwe nyuma y'ubuzima.

Ubushakashatsi bushya bwiyongereye mubushakashatsi bwubuzima kandi bugaragaza akamaro ko gutsimbataza ingeso zimwe na zimwe zubuzima hakiri kare.

Kenneth Boockvar, MD, umuyobozi w'ikigo gishinzwe ubushakashatsi bwimbitse ku gusaza muri kaminuza ya Alabama, yagize ati: "Ukuntu ufite ubuzima bwiza iyo ufite imyaka 60, 70 cyangwa 80 biterwa rwose nibyo wakoze mu myaka mirongo yakubanjirije." Birmingham. ”Ariko ntiyagize uruhare mu bushakashatsi.

Yongeyeho ko hakiri kare gutanga ibyifuzo byihariye bishingiye ku bushakashatsi bushya, ariko ko abantu bashaka gukomeza kugira ubuzima bwiza mu myaka 60 bagomba gutangira kwita ku mirire yabo ndetse n’imibereho yabo mu myaka ya za 40 na 50.

Gusaza byanze bikunze, ariko guhindura imibereho birashobora kongera ubuzima bwiza

Ubushakashatsi bushya bwerekana ko molekile na mikorobe bifitanye isano no gusaza bigabanuka mu bihe byihariye by’ubuzima, ariko ubushakashatsi burakenewe kugira ngo hamenyekane niba impinduka zimwe za molekile zibaho mu bantu batandukanye.

Snyder ati: "Turashaka gusesengura abantu benshi mu gihugu hose kugira ngo tumenye niba ibyo twabonye bireba buri wese - atari abantu bo mu karere ka Bay gusa." "Turashaka gusesengura itandukaniro riri hagati y'abagabo n'abagore. Abagore baramba kandi turashaka kumva impamvu."

Gusaza byanze bikunze, ariko impinduka zimwe mubuzima zirashobora gufasha kugabanya ibyago byindwara ziterwa no gusaza. Ariko, ibindi bintu byinshi nkibidukikije, ihungabana ry’amafaranga, ubuvuzi n’amahirwe yo kwiga nabyo bigira ingaruka ku gusaza kwiza kandi biragoye kubantu kugenzura.

Snyder yavuze ko abantu bashobora guhindura imibereho mito nko gukomeza kugira amazi kugira ngo babungabunge ubuzima bw'impyiko, kubaka imitsi hamwe n'amahugurwa y'ibiro ndetse no gufata imiti ya cholesterol niba cholesterol ya LDL yazamutse.

Yongeyeho ati: "Ibi ntibishobora guhagarika gusaza, ariko bizagabanya ibibazo tubona kandi bifashe kwagura ubuzima bwabo."

Niki cyakorwa kugirango gutinda gusaza?

Kimwe mu bintu byingenzi bidindiza gusaza ni ugukomeza ubuzima bwiza. Ibi birimo kurya indyo yuzuye ikungahaye ku mbuto, imboga, ibinyampeke byose hamwe na poroteyine yuzuye. Kwirinda ibiryo bitunganijwe, isukari irenze, hamwe namavuta atari meza birashobora gufasha kugabanya uburibwe mumubiri no gushyigikira ubuzima muri rusange. Kugumana amazi meza unywa amazi menshi nabyo ni ngombwa kugirango ubungabunge uruhu ningingo.

Imyitozo ngororangingo isanzwe nikindi kintu cyingenzi cyimibereho myiza kandi irashobora gufasha gutinda gusaza. Imyitozo ngororangingo ifasha kuzamura ubuzima bwumutima nimiyoboro yimitsi, kugumana imitsi, no gushyigikira muri rusange kugenda no guhinduka. Kwitabira ibikorwa nko kugenda, koga, yoga cyangwa imyitozo yimbaraga birashobora gufasha umubiri wawe kugaragara nkumuto kandi ufite imbaraga.

Usibye imirire n'imyitozo ngororamubiri, gucunga ibibazo ni ngombwa mugutinda gusaza. Guhangayika karande birashobora kugira ingaruka mbi kumubiri, biganisha ku gutwika no kutagabanuka k'umubiri. Kwimenyereza uburyo bwo kugabanya imihangayiko nko gutekereza, guhumeka cyane, cyangwa gutekereza birashobora gufasha guteza imbere kuruhuka no kumererwa neza muri rusange.

Ikindi kintu cyingenzi cyo gutinda gusaza ni ugusinzira bihagije. Gusinzira ni ngombwa mu gusana umubiri no kuvugurura, kandi kubura ibitotsi byiza bishobora gutera gusaza imburagihe. Gushiraho gahunda yo gusinzira bisanzwe no gukora igihe cyo kuryama kiruhura birashobora gufasha kunoza ibitotsi no gushyigikira ubuzima muri rusange.

Usibye ibintu byubuzima, hariho uburyo butandukanye bushobora gufasha gutinda gusaza. Ibi bishobora kubamo gahunda yo kwita ku ruhu, uburyo bwo kwisiga, hamwe nubuvuzi. Gukoresha izuba hamwe no gutobora uruhu rwawe birashobora gufasha kwirinda kwangirika kwizuba no gukomeza kugaragara mubusore. Uburyo bwo kwisiga nka Botox, ibyuzuza, hamwe nubuvuzi bwa laser birashobora kandi gufasha kugabanya isura yiminkanyari n'imirongo myiza.

Byongeye kandi, hari inyongera zirwanya gusaza zirahari zishobora gushyigikira ubuzima muri rusange nubuzima. Mubyongeweho nibimenyetso bya siyansi byunganira uruhare rwabo mukuzamura ubuzima bwa mitochondial no gutinda gusaza harimo NAD + preursors na urolithin A.

NAD + inyongera

Ahari mitochondriya, hari NAD + (nicotinamide adenine dinucleotide), molekile ikenewe kugirango umusaruro mwinshi ugabanuke. NAD + isanzwe igabanuka uko imyaka igenda isa, bisa nkaho bihuye no kugabanuka kwimyaka kumikorere ya mito-iyambere.

Ubushakashatsi bwerekana ko mu kuzamura NAD +, ushobora kongera ingufu za mito-iyambere kandi ukirinda guhangayikishwa nimyaka. Inyongera ya NAD + ibanziriza irashobora kunoza imikorere yimitsi, ubuzima bwubwonko, hamwe na metabolism mugihe ishobora kurwanya indwara zifata ubwonko. Byongeye kandi, bigabanya kwiyongera ibiro, kunoza insuline, no kugabanya urugero rwa lipide, nko kugabanya cholesterol ya LDL.

Coenzyme Q10

Kimwe na NAD +, coenzyme Q10 (CoQ10) igira uruhare rutaziguye kandi rukomeye mugukora ingufu za mito-iyambere. Kimwe na astaxanthin, CoQ10 igabanya imihangayiko ya okiside, ikomoka ku musaruro w’ingufu za mito-iyonona cyane iyo mitochondriya itameze neza. Kwiyongera hamwe na CoQ10 bigabanya ibyago byo kurwara umutima, ubwonko n'urupfu. Urebye ko CoQ10 igabanuka uko imyaka igenda ishira, kuzuza CoQ10 birashobora gutanga inyungu zo kuramba kubantu bakuze.

Urolithin A.

Urolithin A (UA) ikorwa na bagiteri zo mu nda nyuma yo kurya polifenole iboneka mu biribwa nk'amakomamanga, strawberry, na walnuts. Kwiyongera kwa UA mu mbeba zimaze imyaka ikora sirtuins kandi byongera NAD + ningufu zingirabuzimafatizo. Icy'ingenzi, UA yerekanwe gukuraho mitochondriya yangiritse ku mitsi y’abantu, bityo igatera imbaraga, kurwanya umunaniro, ndetse n’imikorere ya siporo. Kubwibyo, inyongera ya UA irashobora kongera igihe cyo kurwanya gusaza imitsi.

Spermidine

Kimwe na NAD + na CoQ10, spermidine ni molekile isanzwe ibaho igabanuka uko imyaka igenda ishira. Kimwe na UA, spermidine ikorwa na bagiteri zo munda kandi igatera mitofagy - kuvanaho mitochondriya itameze neza, yangiritse. Ubushakashatsi ku mbeba bwerekana ko inyongera ya spermidine ishobora kurinda indwara z'umutima no gusaza kw'imyororokere y'abagore. Byongeye kandi, spermidine yimirire (iboneka mubiribwa bitandukanye birimo soya nintete) byongera kwibuka mumbeba. Harakenewe ubushakashatsi bwinshi kugirango hamenyekane niba ibyo byagaragaye bishobora kwigana abantu.

Suzhou Myland Pharm & Nutrition Inc ni uruganda rwanditswe na FDA rutanga urolithine nziza kandi nziza cyane.

Muri Pharm ya Suzhou Myland twiyemeje gutanga ibicuruzwa byiza cyane kubiciro byiza. Urolithin Yacu Ifu irageragezwa cyane kugirango isukure nimbaraga, ikwemeza ko ubona inyongera nziza-nziza ushobora kwizera. Waba ushaka gushyigikira ubuzima bwimikorere, kuzamura sisitemu yumubiri cyangwa kuzamura ubuzima muri rusange, ifu ya Urolithin Ifu niyo ihitamo neza.

Hamwe nuburambe bwimyaka 30 kandi itwarwa nubuhanga buhanitse hamwe nuburyo bunoze bwa R&D, Pharm ya Suzhou Myland Pharm yateje imbere ibicuruzwa bitandukanye byapiganiwe kandi ihinduka ubuzima bushya bwa siyanse yubuzima, synthèse progaramu na sosiyete ikora serivise.

Mubyongeyeho, Suzhou Myland Pharm nayo ikora FDA yemewe. Ibikoresho bya sosiyete R&D, ibikoresho byububiko, nibikoresho byisesengura nibigezweho kandi bikora byinshi, kandi birashobora gukora imiti kuva kuri miligarama kugeza kuri toni mubipimo, kandi ikubahiriza ibipimo bya ISO 9001 nibisobanuro byakozwe na GMP.