YDL223C (HBT1) ikora ifu Nomero ya CAS: 489408-02-8 Isuku ya 99% ku bikoresho by'inyongera
Videwo y'ibicuruzwa
Ibipimo by'ibicuruzwa
| Izina ry'igicuruzwa | HBT1 |
| Irindi zina | YDL223C |
| Nimero ya CAS | 489408-02-8 |
| Ifishi y'ingirabuzimafatizo | C16H17F3N4O2S |
| Uburemere bwa molekile | 386.40 |
| Ubwiza | 99.0% |
| Isura | Igiti cy'umuhondo woroshye |
| Gupakira | 1kg kuri buri gafuka 25kg kuri buri ngoma |
| Porogaramu | imiti ya nootropic |
Intangiriro y'ibicuruzwa
HBT1 ifatana n'agace gahuza ligand ka α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMPA-R) mu buryo bushingiye kuri glutamate. Ibi bivuze ko HBT1 ari molekile ishobora gufatana gusa n'ahantu runaka kuri poroteyine ya AMPA-R iyo glutamate ihari, kandi uku gufatana bifasha kugenzura imikorere ya poroteyine. Receptors za AMPA zigaragara mu buryo bwose bw'imitsi kandi zigira uruhare runini mu itumanaho ry'imitsi, gutunganya ibyumviro, kwiga, kwibuka, no gukora neza kwa synapse. Receptors za AMPA zigira uruhare runini mu gutumanaho kw'imitsi, zikora vuba kandi vuba mu gutumanaho kw'imitsi myinshi, kandi zigira uruhare mu gusubiza glutamate mu ntangiriro mu duce twa synapse. Receptors za AMPA zikunze guhurira hamwe na receptors za NMDA kuri synapse, kandi hamwe hamwe ziteza imbere inzira za synapse plasticity zigize uruhare mu kwiga, kwibuka, uburozi, no kurinda ubwonko. Brain-derived neurotrophic factor (BDNF) ni neurotrophic factor igira uruhare runini mu kubungabunga no kwagura neuron, kandi igira ingaruka zikomeye kandi nyinshi ku kwiyongera, gutandukanya, kubaho no gupfa kw'uturemangingo tw'imitsi n'ututari two mu mitsi. , igikoresho cy'imitsi gituma neurotransmitter ikora neza mu kwiga no kwibuka. Kubwibyo, ni ingenzi ku buzima n'imibereho myiza y'uturemangingo tw'imitsi.
Ikiranga
(1) Ubuziranenge bukabije: HBT1 ishobora kubona ibicuruzwa bifite ubuziranenge buhanitse binyuze mu gutunganya umusaruro. Ubuziranenge buhanitse busobanura ko binyabuzima biboneka neza kandi ingaruka mbi zikaba nke.
(2) Umutekano: Byagaragaye ko HBT1 ari nziza ku mubiri w'umuntu.
(3) Gutuza: HBT1 ifite ugutuza gukomeye kandi ishobora gukomeza imikorere yayo n'ingaruka zayo mu bidukikije bitandukanye no mu buryo butandukanye bwo kubika.
Porogaramu
HBT1 ni umuti ushya wa AMPA receptor enhancer ufite agonism nke, utera gukora neurotrophic factor (BDNF) ikomoka ku bwonko kandi ugira ingaruka nke ku mitsi y’ibanze. HBT1 ifatana n’urwego rwa AMPA-R ruhuza ligand mu buryo bushingiye kuri glutamate. Hamwe na hamwe, bateza imbere inzira za synaptic plasticity zigize uruhare mu kwiga, kwibuka, gushyuha, no kurinda ubwonko. Bishobora kunoza ubushobozi bw’ubwonko bwo gutekereza no kwibuka, no kongera ubushobozi bw’abantu bwo kwiga. Akenshi yongerwa mu ndyo ya buri munsi mu buryo bw’inyongera mu mirire.
