1,4-DihydronicotinaMide Riboside ifu ikora Nomero ya CAS: 19132-12-8 98% ubuziranenge bw'ibicuruzwa by'inyongera
Ibipimo by'ibicuruzwa
| Izina ry'igicuruzwa | 1,4-DihydronicotinaMide Riboside |
| Irindi zina | 1,4-DIHYDRONICOTINAMIDE RIBOSIDE1-[(3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,4-dihydropyridine-3-carboxamideSCHEMBL188493711-[(3R,4S,5R)-3,4-DIHYDROXY-5-(HYDROXYMETHYL)OXOLAN-2-YL]-4H-PYRIDINE-3-CARBOXAMIDE |
| Nimero ya CAS | 19132-12-8 |
| Ifishi y'ingirabuzimafatizo | C11H16N2O5 |
| Uburemere bwa molekile | 256.26 |
| Ubwiza | 98% |
| Isura | Ifu y'umweru |
| Gupakira | 1kg/umufuka; 25kg/ingoma |
| Porogaramu | Ibikoresho fatizo by'inyongeramusaruro ku mirire |
Intangiriro y'ibicuruzwa
1,4-dihydronicotinamide riboside, izwi kandi nka NRH.Uburyo bwa NRH bwagabanutse ni ikintu gikomeye cya NAD+ gifasha kongera ingano yacyo mu turemangingo.
Mbere na mbere, ni ngombwa gusobanukirwa uruhare rwa NAD+ mu mubiri. NAD+ ni coenzyme igira uruhare mu mikorere myinshi y’uturemangingo, harimo imikorere y’ingufu, gusana ADN, no kugaragaza ingirabuzima fatizo. Uko tugenda dusaza, urugero rwa NAD+ rugabanuka, ibyo bikaba byaragaragaye mu gusaza no mu ndwara ziterwa no gusaza. Ibi byatumye abantu benshi bashishikazwa no kumenya molekile zishobora kongera urugero rwa NAD+ mu mubiri, kandi 1,4-dihydronicotinamide riboside ni imwe muri izo molekile.
1,4-dihydronicotinamide riboside ni igikoresho gikomeye cya NAD+, kandi ubushakashatsi bwagaragaje ko gishobora kuzamura neza urugero rwa NAD+ mu turemangingo. Ibi byatumye havugwa ko inyongera ya 1,4-dihydronicotinamide riboside ishobora kugira ubushobozi bwo kuvura indwara zitandukanye z’ubuzima, harimo indwara ziterwa n’imikorere y’umubiri, indwara ziterwa n’ubwonko, ndetse no kugabanuka kw’izabukuru.
Mu by’ukuri, hari ibimenyetso bigaragaza ko 1,4-dihydronicotinamide riboside ishobora kuba ifite akamaro kurusha molekile yayo nyamukuru, nicotinamide riboside, mu kongera urugero rwa NAD+. Ibi biterwa nuko 1,4-dihydronicotinamide riboside ari ikintu kigabanya imbaraga cyane, bivuze ko ari cyo cyiza mu gutanga electron mu nzira ya NAD+. Kubera iyo mpamvu, ifite ubushobozi bwo gutera imbaraga mu gukora NAD+ mu turemangingo.
Uretse uruhare rwayo mu gukora NAD+ biosynthesis, 1,4-dihydronicotinamide riboside ifite kandi imiterere ya antioxydant. Umuvuduko wa oxidative, ukomoka ku kutumvikana hagati ya free radicals na antioxydants mu mubiri, uterwa n'indwara nyinshi, zirimo kanseri, indwara z'umutima n'imitsi, ndetse n'indwara zo kwangirika kw'imitsi. Mu gukuraho free radicals no kugabanya kwangirika kwa oxidative, 1,4-dihydronicotinamide riboside ishobora gutanga inyungu z'inyongera ku buzima uretse uruhare rwayo nk'intangiriro ya NAD+.
Ikiranga
(1) Ubuziranenge bukabije: 1,4-dihydronicotinamide riboside ishobora kubona ibicuruzwa bifite ubuziranenge buhanitse binyuze mu nganda zitunganijwe neza. Ubuziranenge buhanitse busobanura ko binyabuzima biboneka neza kandi ingaruka mbi zikaba nke.
(2) Umutekano: 1,4-dihydronicotinamide riboside ni ikintu karemano cyagaragaye ko gifite umutekano ku mubiri w'umuntu.
(3) Gutuza: 1,4-dihydronicotinamide riboside ifite ubutuza bwiza kandi ishobora gukomeza imikorere n'ingaruka zayo mu bidukikije bitandukanye no mu buryo butandukanye bwo kubika.
Porogaramu
1,4-Dihydronicotinamide ni ubwoko bwa nicotinamide riboside bugabanutse. Ishobora kubaho haba mu buryo bwa oxidized cyangwa bugabanutse kandi ni icyerekezo cya NAD nshya yavumbuwe (nicotinamide adenine dinucleotide), iboneka nk'inyongera, aho NRH ari yo nkomoko ya NAD+ ikomeye kandi yihuta kurusha NR.
