7,8-Dihydroxyflavone nikintu gisanzwe kiboneka mu bimera cyitabiriwe cyane ninyungu zishobora kuba kumikorere yubwonko no kwibuka. Uru ruganda rwa flavone ni urwego rwimiti yitwa flavonoide, izwiho kurwanya antioxydeant na anti-inflammatory. Ubushakashatsi bwerekanye ko 7,8-dihydroxyflavone ishobora kugira ingaruka nziza mubwonko.
7,8-Dihydroxyflavone ni uruganda rukomeye kandi rutandukanye rwumuryango wa flavonoid. Flavonoide ni ibintu bisanzwe bikwirakwizwa cyane mu bimera kandi bigira uruhare runini muburyo butandukanye bwibinyabuzima. Imwe mu mico idasanzwe ya 7,8-dihydroxyflavone nubushobozi bwayo bwo gukorana no kugenzura poroteyine na enzymes mu mubiri, byatumye abantu bashishikazwa n’ubumenyi.
Ubushakashatsi bwerekanye ko ibice 7,8-dihydroxyflavone bifite akamaro kanini ku buzima, bifite antioxydants, anti-inflammatory na neuroprotective. Muri byo, ibikorwa bikomeye bya antioxydeant ya 7.8-dihydroxyflavone ituma ikuraho radicals yangiza mu mubiri kandi ikarinda guhagarika okiside itera kwangirika kwindwara nindwara zitandukanye. Ubushakashatsi bwakozwe kugeza ubu kuri 7.8-dihydroxyflavone burashimishije, ariko harakenewe ubushakashatsi bwinshi kugirango hamenyekane imikorere n’umutekano bya 7.8-dihydroxyflavone yo gukoresha mu bantu. Nubwo bimeze bityo, iyi flavonoid compound ifite amasezerano akomeye nkumuntu ushobora kuzuza ibiryo cyangwa umukandida wibiyobyabwenge mugihe kizaza.
7,8-Dihydroxyflavone ni uruganda rusanzwe, ruzwi kandi nka 7,8-DHF, rwitabiriwe cyane mumyaka yashize kubera inyungu zishobora kugirira ubuzima bwabantu.
Iyi mvange isanzwe iboneka mumuryango wa flavonoid kandi iboneka mubihingwa bitandukanye, harimo umuzi wa Scutellaria baicalensis.
1. Kunoza imikorere yubwenge
Ubushakashatsi bwerekana ko iyi compound ikora nka TrkB agonist, bivuze ko ikora reseptor ya TrkB mubwonko. Izi reseptors zifite inshingano zo guteza imbere imikurire no kubaho kwa neuron, ndetse no kongera plastike ya synaptic - ubwonko bwo guhuza no guhinduka. Mugukangura reseptor ya TrkB, 7,8-dihydroxyflavone yerekanwe kunoza kwibuka no kumenya. Ibi bituma ishobora kuvura imiti ivura indwara zifata ubwonko nkindwara ya Alzheimer.
2. Ingaruka zo kurwanya imiti
Mugukoresha reseptor ya TrkB, urugimbu ruteza imbere imikurire ya neuron nshya muri hippocampus, agace k'ubwonko bugira uruhare mukugenzura imyumvire. Ubushakashatsi bw’inyamanswa bwerekanye ko 7,8-dihydroxyflavone ishobora kugabanya ibimenyetso byo kwiheba no kongera imbaraga zo kurwanya imihangayiko. Ubu bushakashatsi bwerekana ko iyi nteruro ishobora gukoreshwa nkuburyo busanzwe bwa antidepressants gakondo.
3. Kurwanya inflammatory nubushobozi bwa antioxydeant
7,8-Dihydroxyflavone ni antioxydants ikomeye ifasha kurinda selile imbaraga za okiside iterwa na radicals yubuntu. Uku kurinda kugabanya ibyago byindwara zidakira kandi bidindiza gusaza.
Gutwika ubwonko birashobora kugira uruhare mu iterambere no gutera imbere kwindwara zitandukanye zifata ubwonko, harimo indwara ya Parkinson na sclerose nyinshi. Ubushakashatsi bwerekana ko 7,8-DHF ifite imiti igabanya ubukana ifasha kugabanya ubwonko mu bwonko no kwirinda neurodegeneration. Muguhagarika umusaruro wa molekile ziterwa na inflammatory, uruganda rushobora kugira ubushobozi bwo kugabanya ibimenyetso no gutinda kwiterambere kwizi ndwara zica intege.
4. Ifite ubushobozi bwo kuvura ibibazo byo guhangayika
Ubushakashatsi bw’inyamaswa bwerekanye ko uruganda rushobora kugabanya imyitwarire isa n’amaganya ukoresheje reseptor ya TrkB muri amygdala, agace k'ubwonko kagira uruhare mu gutinya no gukemura ibibazo. Muguhindura ibikorwa byaba reseptors, 7,8-dihydroxyflavone irashobora gutanga inzira karemano kandi nziza yo gucunga amaganya nta ngaruka mbi zijyanye n'imiti gakondo yo kurwanya amaganya.
Mbere yo gucengera mubiribwa, reka twumve icyo 7,8-dihydroxyflavone aricyo. Nibisanzwe biboneka flavonoide iri mubyiciro bya flavonoide. Flavonoide ni ibimera bishingiye ku bimera bizwiho kurwanya antioxydeant, bifasha kurinda ingirabuzimafatizo zangiza.
Noneho, reka dusuzume ibiryo bimwe na bimwe birimo 7.8-dihydroxyflavone:
1. Imbuto za Citrusi
Imwe mu masoko meza ya 7,8-dihydroxyflavone ni imbuto za citrusi nk'amacunga, indimu, imizabibu n'indimu. Izi mbuto ntizikungahaye kuri vitamine C gusa, ahubwo zirimo na flavonoide zitandukanye, harimo 7,8-dihydroxyflavone.
2. Imbuto
Imbuto nka blueberries, strawberry, raspberries, na blackberries zizwiho kuba zifite antioxydants nyinshi. Izi mbuto ziryoshye nazo nisoko ikomeye ya 7,8-dihydroxyflavone, iguha inyungu zubuzima kabiri.
Shokora yijimye
Amakuru meza kubakunzi ba shokora! Shokora yijimye, cyane cyane ifite kakao nyinshi, irimo urugero rwa 7.8-dihydroxyflavonoide. Ariko, hitamo ubwoko butandukanye hamwe nisukari nkeya yongeyeho isukari kugirango ubone inyungu zuzuye.
4. Icyayi kibisi
Usibye kuba ikinyobwa gikunzwe, icyayi kibisi gikungahaye kuri flavonoide, harimo 7,8-dihydroxyflavone. Kunywa icyayi kibisi buri gihe birashobora kugufasha kongera antioxydeant kandi bigafasha ubuzima muri rusange.
5. Soya
Niba ushaka isoko y'ibimera ya 7,8-dihydroxyflavone, soya ni amahitamo meza. Ntabwo ari nyinshi kuri poroteyine gusa, ahubwo zirimo na flavonoide zitandukanye zigira uruhare mu nyungu zazo.
6. Imboga rwatsi
Imboga nka kale, epinari, na broccoli ntabwo ziri munsi ya karori gusa, ahubwo zikungahaye kuri antioxydants. Icyatsi kibabi ni isoko nziza ya 7,8-dihydroxyflavone, hamwe nintungamubiri zingenzi.
7. Divayi itukura
Muraho! Kunywa mu rugero rwa vino itukura birimo ubwoko bwa flavonoide bita resveratrol, irimo 7,8-dihydroxyflavone. Uru ruganda rutekereza ko ruzagira uruhare mu nyungu z'umutima-damura zijyanye no kunywa vino itukura.
Kwinjiza ibyo biryo mumirire yawe birashobora kuguha inyungu nyinshi zijyanye na 7,8-dihydroxyflavone.
7,8-Dihydroxyflavone, izwi kandi nka DHF cyangwa baicalein, ni flavonoide isanzwe iboneka mu bimera bitandukanye, harimo n'umuzi wa Scutellaria baicalensis. Uru ruganda rwitabiriwe cyane mumyaka yashize kubera inyungu zishobora guteza ubuzima hamwe nubuvuzi. Ariko, iyo usuzumye umutekano wibintu byose, ni ngombwa gusuzuma ibimenyetso bya siyansi bihari. None, 7,8-dihydroxyflavone ifite umutekano?
Ku bijyanye n’umutekano wacyo, ubushakashatsi buke bwakozwe ku bijyanye no kurya abantu 7.8-dihydroxyflavone. Kubwibyo, kuvuga byimazeyo kubyerekeye umutekano wacyo biragoye. Nyamara, ubushakashatsi bwinyamanswa bwatanze ubushishozi bwingirakamaro muburozi bwabwo. Ubwoko butandukanye bwinyamanswa bwatangaje ko nta ngaruka zikomeye zikurikira ubuyobozi bwa DHF, ndetse no kuri dosiye nyinshi. Ibi birerekana ko 7,8-dihydroxyflavone ishobora kwihanganira neza, byibuze mubipimo byizwe.
Ariko, ugomba kwitonda mugihe ufata imyanzuro ishingiye gusa kubushakashatsi bwinyamaswa. Ingaruka zibintu zirashobora gutandukana cyane hagati yubwoko, kubwibyo, birasabwa kwitonda mugihe cyohereza ibisubizo kubantu. Byongeye kandi, kubura ubushakashatsi bwigihe kirekire bwabantu bwabujije gusuzuma neza umutekano wabwo.
7,8-Dihydroxyflavone (7,8-DHF) ni flavonoide isanzwe ibaho yitabiriwe cyane ninyungu zishobora guteza ubuzima, icyakora, ni ngombwa cyane kumenya ibipimo byasabwe hamwe nibyifuzo mugihe ukoresheje 7,8-DHF ngombwa.
Ni ngombwa kugisha inama inzobere mu by'ubuzima ku bijyanye na dosiye ya 7,8-DHF, kuko urugero rukwiye rushobora gutandukana bitewe n'impamvu nyinshi nk'imyaka, ibiro ndetse n'ubuvuzi bwihariye. Ubu bushakashatsi burerekana uburyo butandukanye bwa dosiye, mubisanzwe 20 kugeza kuri 60 mg kumunsi. Ariko, twakagombye kumenya ko ibyo byifuzo bidashyizwe mumabuye kandi birashobora guhinduka mugihe ibimenyetso byinshi bya siyansi byakusanyijwe.
Mugihe uguze 7,8-DHF yinyongera yimirire, nibyingenzi guhitamo uruganda ruzwi kandi rwizewe kugirango umutekano wibikorwa nibicuruzwa. Gusoma ibyasuzumwe byabakiriya no kugenzura ibizamini bya laboratoire birashobora kandi kugufasha kumenya ibicuruzwa byizewe. Ni ngombwa cyane gukurikiza inama zinzobere mu buvuzi. Bazashobora gutanga ubuyobozi bwihariye ukurikije amateka yawe yubuvuzi nubuzima bwubu. Buri gihe birasabwa gutangirana nigipimo gito cyane kandi kigenda cyiyongera buhoro buhoro nkuko bikenewe iyobowe ninzobere mubuzima.
Mbere yo kwinjiza 7,8-DHF muburyo bwawe bwa buri munsi, ni ngombwa kumenya ingaruka zose zishobora gutera cyangwa ibiyobyabwenge. Nubwo muri rusange 7,8-DHF yihanganirwa neza, abantu bamwe bashobora guhura nibibazo byoroheje byigifu cyangwa allergie. Kandi, menyesha kumenyesha inzobere mu buvuzi imiti iyo ari yo yose cyangwa inyongera urimo gufata kugirango wirinde imikoranire ishobora kuba. Wibuke ko gufata inyongeramusaruro zose zigomba guhora ziyobowe ninzobere mubuzima kugirango ubuzima bwawe bugerweho.
Ikibazo: Bitwara igihe kingana iki kugirango 7.8-dihydroxyflavoneor ikore?
Igisubizo: Umuvuduko 7,8-dihydroxyflavone (7,8-DHF) utangira gukurikizwa urashobora gutandukana bitewe nibintu byinshi. Mu bushakashatsi bwa siyansi, 7,8-DHF yerekanye ko ifite ingaruka zitandukanye, nko guteza imbere irekurwa rya neurotrophique na neuroprotection. Igihe bifata kugirango izi ngaruka zigaragare zirashobora kuva kumasaha kugeza kumunsi cyangwa ndetse birebire, bitewe nuburyo bwihariye bwibikorwa nintego yikigo.
Inshingano: Iyi ngingo igamije amakuru gusa kandi ntigomba gufatwa nkinama zubuvuzi. Buri gihe ujye ubaza inzobere mu by'ubuzima mbere yo gukoresha inyongera cyangwa guhindura gahunda z'ubuzima.
Igihe cyo kohereza: Nyakanga-04-2023
