7,8-Dihydroxyflavone (7,8-DHF) ikora ifu Nomero ya CAS: 38183-03-8 98.0% ubuziranenge bw'ibicuruzwa by'inyongera
Videwo y'ibicuruzwa
Ibipimo by'ibicuruzwa
| Izina ry'igicuruzwa | 7,8-Dihydroxyflavone |
| Irindi zina | 7,8-DIHYDROXYFLAVONE; 7,8-dihydroxy-2-phenyl-4-benzopyrone; DIHYDROXYFLAVONE, 7,8- (RG); 7,8-Dihydroxyflavone hydrate; 7,8-dihydroxy-2-phenyl-1-benzopyran-4-imwe |
| Nimero ya CAS | 38183-03-8 |
| Ifishi y'ingirabuzimafatizo | C15H10O4 |
| Uburemere bwa molekile | 254.24 |
| Ubwiza | 98.0% |
| Isura | Ifu y'umuhondo |
| Porogaramu | Inyongeramusaruro ku biribwa |
Intangiriro y'ibicuruzwa
7,8-Dihydroxyflavone, izwi kandi nka 7,8-DHF, ni flavonoide isanzwe iboneka mu bimera bitandukanye, harimo na Tridacna tridacna. Izwiho ubushobozi bwayo bwo kurwanya antioxidant no gutuma ubwonko bukora neza, kimwe mu bintu bishimishije kuri 7,8-dihydroxyflavone ni ubushobozi bwayo bwo gushyigikira ubuzima bw'ubwonko no kunoza imikorere y'ubwonko. Ubushakashatsi bwerekana ko iyi nyunganiramirire ikora nk'inyunganiramirire ikomeye, ikangura imikurire n'ubuzima bw'uturemangingo tw'ubwonko. Ubushakashatsi bwakorewe ku nyamaswa zo muri laboratwari bwagaragaje ko 7,8-DHF irushaho kunoza ubushobozi bwo kwibuka no kwiga. Mu guteza imbere ishingwa ry'imibanire mishya ya synaptic no kongera itumanaho hagati y'uturemangingo tw'ubwonko, iyi nyunganiramirire isezeranya gufungura ubushobozi bwacu bwo gutekereza. Byongeye kandi, 7,8-dihydroxyflavone ikorana na serotonin receptors zo mu bwonko, zigira uruhare mu kugenga amarangamutima. Mu guhindura izi nyunganiramirire, ishobora kugabanya ibimenyetso by'imihangayiko n'ihungabana.
Ikiranga
(1) Ubuziranenge bwinshi: 7,8-Dihydroxyflavone ishobora kubona ibintu bifite ubuziranenge bwinshi binyuze mu gukuramo ibintu mu buryo bw’umwimerere no mu buryo bwo gukora neza. Ubuziranenge bwinshi busobanura ko binyabuzima biboneka neza kandi ingaruka mbi nke zikaba nke.
(2) Umutekano: 7,8-Dihydroxyflavone ni ikintu karemano cyagaragaye ko gifite umutekano ku bantu. Mu rugero rw'igipimo, nta burozi cyangwa ingaruka mbi bigira.
(3) Gutuza: 7,8-Dihydroxyflavone ifite ubutuza bwiza kandi ishobora gukomeza imikorere yayo n'ingaruka zayo mu bihe bitandukanye by'ibidukikije n'ububiko.
(4) Byoroshye kwinjiza: 7,8-Dihydroxyflavone ishobora kwinjiza vuba umubiri w'umuntu, ikinjira mu maraso binyuze mu nzira y'amara, igakwirakwira mu ngingo n'ibice bitandukanye by'umubiri.
Porogaramu
7, 8-DHF, nk'ikintu gifasha cyane mu kurinda imikorere y'uturemangingo twa TrkB, gishobora kugira uruhare mu kurinda imikorere y'uturemangingo, kuvugurura imikorere y'uturemangingo, kugenzura uburyo imikorere y'uturemangingo ihinduka, nibindi binyuze mu kwigana uburyo BDNF ihurira na TrkB no gukora inzira z'amajwi zo hasi, kugira ngo birusheho kunoza ibimenyetso by'uburyo umuntu yiga amarangamutima n'uburyo yibuka ibintu, kugabanuka k'ubushobozi bwo gutekereza, kugabanuka k'imikorere y'imitsi n'ibindi bimenyetso by'indwara z'imitsi nk'indwara ya Alzheimer cyangwa inyamaswa zishaje, no kugabanya imiterere y'indwara zo mu mutwe n'inyamaswa zibyibushye cyane. Hagati aho, kugeza ubu, nta ngaruka mbi zikomeye za 7,8-DHF zabonetse mu nyamaswa zakorewe igerageza. 7,8-DHF ifite ubushobozi n'agaciro gakomeye mu gukumira no kuvura ibibazo bijyanye na BDNF/TrkB.
