NRC CAS No.: 23111-00-4 98.0% isuku min.Kurwanya gusaza
Ibipimo byibicuruzwa
| Izina RY'IGICURUZWA | Nikotinamide Riboside Chloride |
| Irindi zina | NicotinamideB-DRibosideChloride (WX900111); NikotinamideRiboside.Cl; Nicotimideribosidechloride; Pyridinium, 3- (aminocarbonyl) -1-β-D-ribofuranosyl-, chloride (1: 1); 3-karbamoyl-1 - ((2R, 3R, 4S, 5R) -3,4-dihydroxy-5- (hydroxymethyl) tetrahydrofuran-2-yl) pyridin-1-iumchloride; 3-Carbamoyl-1- (β-D-ribofuranosyl) pyridiniumchloride; 3-Carbamoyl-1-beta-D-ribofuranosylpyridiniumchloride |
| URUBANZA No. | 23111-00-4 |
| Inzira ya molekulari | C11H15ClN2O5 |
| Uburemere bwa molekile | 290.7 |
| Isuku | 98.0% |
| Kugaragara | Ifu yera kugeza yera |
| Gusaba | Ibyokurya byongera ibiryo |
Kumenyekanisha ibicuruzwa
Nikotinamide Riboside Chloride ni biomolecule kandi ikomoka kuri vitamine B3 ishobora kwinjizwa no guhinduranya umubiri wumuntu kugirango ibe intangiriro ya coenzyme NAD + (nicotinamide adenine dinucleotide).Coenzyme NAD + igira uruhare runini mumubiri wumuntu, harimo imbaraga za metabolisme yingirabuzimafatizo, gusana ADN, na apoptose selile.
Ingaruka zibinyabuzima za Nikotinamide Riboside Chloride zakozweho ubushakashatsi bwimbitse.Irashobora guteza imbere imikorere ya mito-iyambere, bityo igahindura imbaraga za selile metabolism.Uku kwiyongera kwingufu za metabolisme birashobora kugirira akamaro ubuzima bwumutima nimiyoboro y'amaraso, kwihanganira imitsi, hamwe n'indwara ya metabolike.Byongeye kandi, Nicotinamide Riboside Chloride ikekwa ko iteza imbere gusana ADN na apoptose selile, bityo bigafasha kwirinda kanseri n'izindi ndwara.
Nikotinamide Riboside Chloride irashobora kandi kongera imikorere yumubiri wumubiri wumuntu, igafasha kurwanya virusi na bagiteri.Ubushakashatsi bwerekanye ko Nikotinamide Riboside Chloride ishobora guteza imbere ibikorwa bya selile zimwe na zimwe z'umubiri, harimo selile zica kamere na CD8 + T.Utugingo ngengabuzima tugira uruhare runini mu kurwanya indwara n'ibibyimba.
Muri rusange, ubushakashatsi kuri Nicotinamide Riboside Chloride buracyari mu ntangiriro kandi hakenewe ubushakashatsi bw’amavuriro kugira ngo bugaragaze ko bukora neza n'umutekano.Nyamara, ingaruka z’ibinyabuzima zakozweho ubushakashatsi cyane kandi bizera ko bifite akamaro kanini kubuzima no kuvura.
Ikiranga
.Mugutanga isoko ya NAD +, Nicotinamide Riboside Chloride irashobora gufasha kunoza ibyo bikorwa no guteza imbere ubuzima muri rusange.
.Ubushakashatsi bwerekana ko inyongera ya Nikotinamide Riboside Chloride ishobora kongera urwego rwa NAD + kandi ikongera mikorobe ya mitochondial, ishobora gufasha kurwanya igabanuka rishingiye ku myaka mu mikorere ya selile.
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.Birasanzwe kandi mubiribwa bimwe na bimwe, nk'amata n'umusemburo, bikarushaho gushyigikira umwirondoro wacyo.
Porogaramu
Nikotinamide Riboside Chloride ni biomolecule yizwe cyane ikomoka kuri vitamine B3 kandi ikora nk'intangiriro ya coenzyme NAD + mu mubiri, ikagira uruhare runini mu binyabuzima.Kugeza ubu, ahantu h’ingenzi muri Nikotinamide Riboside Chloride harimo indwara zifata umutima n’umutima n’ubwonko, indwara zifata ubwonko, indwara ziterwa na metabolike, ndetse no kurwanya gusaza.Kurugero, Nicotinamide Riboside Chloride irashobora gufasha kunoza indwara ziterwa na metabolisme nkindwara zifata umutima nimiyoboro yubwonko nubwonko bwubwonko, diyabete, numubyibuho ukabije wongera imbaraga za metabolisme yingirabuzimafatizo no kunoza imikorere ya mito-iyambere.Byongeye kandi, Nicotinamide Riboside Chloride bemeza ko ifite ubushobozi bwo kurwanya indwara zifata ubwonko no kurwanya gusaza.Ubushakashatsi bwerekanye ko Nicotinamide Riboside Chloride ishobora kuzamura ubushobozi bwubwenge hamwe nimikorere ya sisitemu yimbeba zishaje.
Byongeye kandi, Nicotinamide Riboside Chloride yakoreshejwe mu kuvura indwara ya metabolisme ya uracil, iyi ikaba ari indwara idasanzwe ivuka.
Mugihe ubushakashatsi bwa Nicotinamide Riboside Chloride bukomeje kwiyongera, ibyifuzo byayo biragenda byiyongera.Kurugero, Nicotinamide Riboside Chloride irashobora gukoreshwa nkibiyobyabwenge bivura kanseri.Ubushakashatsi bwerekanye ko Nikotinamide Riboside Chloride ishobora guteza imbere ADN no gusana apoptose, bityo bigafasha kwirinda kanseri n'izindi ndwara.Byongeye kandi, Nicotinamide Riboside Chloride irashobora kongera imikorere yumubiri wumubiri wumuntu, igafasha kurwanya virusi na bagiteri.Izi porogaramu zishobora gutuma Nicotinamide Riboside Chloride imwe mubushakashatsi bugezweho.
Byongeye kandi, uburyo bwa synthesis ya chimique ya Nikotinamide Riboside Chloride ihora itera imbere, kandi nigiciro cyumusaruro uragabanuka, ibyo bikaba binatanga amahirwe menshi yo gukoreshwa mubuvuzi.Kubwibyo, Nicotinamide Riboside Chloride iteganijwe guhinduka biomolecule ifite ibyifuzo byinshi mugihe kizaza.
