Ifu ya Amino Tadalafil nimero ya CAS: 385769-84-6 Isuku ya 98% ku bikoresho by'inyongera
Videwo y'ibicuruzwa
Ibipimo by'ibicuruzwa
| Izina ry'igicuruzwa | Amino Tadalafil |
| Irindi zina | (6R,12aR)-2-Amino-6-(1,3-benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione;AminoTadalafil(6R,12Ar)-2-Amino-6-(1,3-Benzodioxol-5-Yl)-2,3,6,7,12,12A-Hexahydropyrazino[1',2':1,6]Pyrido[3,4-B]Indole-1,4-Dion e;(6R,12aR)-2-Amino-6-(benzo[d][1,3]dioxol-5-yl)-2,3,6,7,12,12a-hexahydropyrazino[1',2':1,6]pyrido[3,4-b]indol-1,4-dione;(6R,12aR)-2-amino-6-(benzo[d][1,3]dioxol-5-yl)-2,3,12,12a-tetrahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4(6H,7H)-dione |
| Nimero ya CAS | 385769-84-6 |
| Ifishi y'ingirabuzimafatizo | C21H18N4O4 |
| Uburemere bwa molekile | 390.39 |
| Ubwiza | 98.0% |
| Isura | Ifu y'umweru kuva kuri umweru kugeza kuri umweru |
| Porogaramu | Inyongeramusaruro ku biribwa |
Intangiriro y'ibicuruzwa
Amino Tadalafil ni ikintu gishya, gikomoka kuri tadalafil, kirimo gukundwa cyane mu bijyanye no kudakora neza kw'igitsina (ED). Ihuza aside amine na tadalafil, irinda PDE5 yemewe na FDA ikoreshwa cyane cyane mu kuvura ED. Ikora mu kongera amaraso ajya mu gitsina, bigatuma abagabo bashobora kugera no gukomeza guhagarara. Ku rundi ruhande, aside amine zigira uruhare runini mu mikorere itandukanye y'umubiri, harimo no gukora poroteyine, ari zo ngirabuzimafatizo z'ingingo n'ingingo. Uruvange rw'ibi bintu bibiri rugamije kongera ubushobozi bwa Tadalafil mu kuvura ED. Kandi amino Tadalafil ni verisiyo nziza ifite ubushobozi budasanzwe, yongera imikorere n'ubushobozi bw'iyabanjirije. Imiterere yayo ya shimi iracyasa na Tadalafil, ariko binyuze mu kwinjiza amatsinda ya amino, igira imiterere yihariye ituma igaragara mu rwego rw'imiti. Kimwe na tadalafil, Amino Tadalafil ikora mu gukumira phosphodiesterase 5 (PDE5), enzyme ishinzwe gusenya guanosine monophosphate (cGMP) mu mubiri. cGMP ni ikintu karemano gifasha imiyoboro y'amaraso kuruhuka, bityo bigatuma amaraso atembera neza. Mu kubuza PDE5, amino Tadalafil ituma cGMP yiyongera, bityo yongera kwaguka kw'amaraso no kunoza imiyoboro y'amaraso. Byongeye kandi, abashakashatsi basuzumye ubushobozi bwayo bwo gufasha kuvura indwara ya prostatic hyperplasia (BPH) binyuze mu gutuma amaraso atembera neza muri prostate.
Ikiranga
(1) Ubuziranenge bwinshi: Amino Tadalafil ishobora kubona ibicuruzwa bifite ubuziranenge bwinshi binyuze mu gutunganya ikorwa ryayo. Ubuziranenge bwinshi busobanura ko binyabuzima biboneka neza kandi ingaruka mbi zikaba nke.
(2) Umutekano: Umutekano mwinshi, ingaruka mbi nke.
(3) Gutuza: Amino Tadalafil ifite ubutuza bwiza kandi ishobora gukomeza imikorere yayo n'ingaruka zayo mu bidukikije bitandukanye no mu buryo butandukanye bwo kubika.
Porogaramu
Amino Tadalafil ni umuti ugabanya ubukana bwa PDE5 ufite ingaruka zimwe na tadalafil. Mu guhuza aside amine na tadalafil, amino Tadalafil ifatwa nk'ifite akamaro kanini mu kuvura ikibazo cyo kuryamana kurusha tadalafil yonyine. Aside amine zishobora gufasha kongera urujya n'uruza rw'amaraso no gushyigikira imikorere myiza y'imiti muri rusange. Byongeye kandi, ishobora kunoza ibimenyetso by'ikibazo cyo kuryamana (ED) ibuza imikorere ya enzyme ya PDE5 kugira ngo amaraso atembera mu myanya ndangagitsina y'abagabo. Ugereranyije na tadalafil, amino Tadalafil igenda buhoro mu mubiri kandi ishobora gutanga ingaruka zirambye. Ibi biha amino Tadalafil ubushobozi bukomeye mu kuvura ED.
