Oleoylethanolamide (OEA) uruganda rukora ifu CAS No.: 111-58-0 98%, 85% byera min. kubintu byongeweho
Ibipimo byibicuruzwa
| Izina ryibicuruzwa | Oleoyl ethanolamide |
| Irindi zina | N-oleoyl ethanolamine; N- (2-hydroxyethyl) -, (Z) -9-Octadecenamide |
| URUBANZA No. | 111-58-0 |
| Inzira ya molekulari | C20H39NO2 |
| Uburemere bwa molekile | 325.53 |
| Isuku | 98.0% ， 85.0% |
| Kugaragara | Ifu nziza yera ya kirisiti |
| Gupakira | 1kg / igikapu ， 25kg / ingoma |
| Gusaba | Kubabara ububabare, kurwanya inflammatory |
Kumenyekanisha ibicuruzwa
Oleoylethanolamide nigice cya kabiri cya amide igizwe na acide lipophilique oleic na hydrophilique ethanolamine. Oleoylethanolamide nayo isanzwe ibaho molekile ya lipide mubindi binyabuzima n'ibimera. Iraboneka cyane mubice byinyamanswa n’ibimera nka paka ya kakao, soya, nimbuto, ariko ibiyirimo ni bike cyane. Gusa iyo ibidukikije byo hanze bihindutse cyangwa ibiryo bikanguwe, ingirangingo z'umubiri z'umubiri Gusa noneho hazakorwa byinshi muribi bintu.
Ku bushyuhe bwicyumba, Oleoylethanolamide nikintu cyera gifite aho gishonga kigera kuri 50 ° C. Irashobora gushonga byoroshye mumashanyarazi ya alcool nka methanol na Ethanol, byoroshye gushonga mumashanyarazi adafite inkingi nka n-hexane na ether, no kudashonga mumazi. OEA ni molekile ya amphifilike isanzwe ikoreshwa nka surfactant na detergent mu nganda zikora imiti. Nyamara, ubushakashatsi bwakozwe bwerekanye ko OEA ishobora gukora nka lipide yerekana molekile mu mara-ubwonko no kwerekana urukurikirane rwibikorwa byibinyabuzima mu mubiri, harimo: kugenzura ubushake bwo kurya, kunoza metabolisme ya lipide, kongera kwibuka no kumenya ndetse nindi mirimo. Muri byo, imikorere ya Oleoylethanolamide yo kugenzura ubushake bwo kurya no kunoza metabolisme ya lipide yitabiriwe cyane.
Oleoylethanolamide irashobora kugaburira ibiryo hamwe ningufu za homeostasis ukoresheje peroxisome prolifator-ikora reseptor-α. Byongeye kandi, Oleoylethanolamide yerekana ibindi bikorwa bijyanye nubuzima, harimo guhindura ibikorwa bihindura inzira ya lysosomal-to-nuclear yerekana inzira yo kuramba no kurinda imitsi igenzura imyitwarire yo kwiheba. Ubushakashatsi bwerekana kandi ko Oleoylethanolamide ishobora kugira ingaruka za neuroprotective. Mu ngero z’inyamaswa, byagaragaye ko bigabanya ibyangiritse biturutse ku bwonko no gukomeretsa ubwonko. Ingaruka ngengamikorere ya Oleoylethanolamide iterwa no guhuza na PPARα, igereranya na reseptor ya retinoide X (RXR) ikanayikora nk'impamvu ikomeye yo kwandikirana igira uruhare mu guhuza ingufu homeostasis, lipid metabolism, autophagy, hamwe no gutwika. intego zo hasi.
Ikiranga
(1) Isuku ryinshi: OEA irashobora kubona ibicuruzwa byera cyane binyuze mugutunganya umusaruro. Isuku ryinshi risobanura bioavailable nziza hamwe na reaction nkeya.
(2) Umutekano: OEA byagaragaye ko ifite umutekano kumubiri wumuntu.
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(4) Biroroshye kubyakira: OEA irashobora kwinjizwa vuba numubiri wumuntu hanyuma igakwirakwizwa mubice bitandukanye.
Porogaramu
Oleoylethanolamide ni lipide isanzwe ya Ethanolamide ikoreshwa mugutegura imirire no kugenzura ibiro byumubiri mubwoko butandukanye bwintangangabo. Ni metabolite ya acide oleic ikorwa mu mara mato y'umuntu. Oleylethanolamide (OEA) ni molekile igenga metabolisme ya lipide na homeostasis. Ifatiye kuri PPAR Alpha yakira kandi ifasha kugenzura ibintu bine: inzara, ibinure byumubiri, cholesterol nuburemere. PPAR Alpha igereranya peroxide prolifator ikoreshwa na reseptor alpha, na bioactive lipid amide oleoylethanolamide (OEA) ifite ibintu bitandukanye byihariye bya homeostatike, harimo ibikorwa byo kurwanya inflammatory, modulisiyo yo gukumira indwara, hamwe ningaruka za antioxydeant.
