Impuzandengo y'ifu ya RU58841 Nomero ya CAS: 154992-24-2 99.0% ubuziranenge bw'ibicuruzwa by'inyongera
Ibipimo by'ibicuruzwa
| Izina ry'igicuruzwa | 4-[3-(4-Hydroxybutyl)-4,4-dimethyl-2,5-dioxo-1-imidazolidinyl]-2-(trifluoromethyl)benzonitrile |
| Irindi zina | RU58841 |
| Nimero ya CAS | 154992-24-2 |
| Ifishi y'ingirabuzimafatizo | C17H18F3N3O3 |
| Uburemere bwa molekile | 369.34 |
| Ubwiza | 99.0% |
| Isura | ifu y'umweru |
| Gupakira | 1kg/umufuka |
| Porogaramu | Gukura umusatsi |
Intangiriro y'ibicuruzwa
RU58841 (izwi kandi nka RU-58841) ni imvange, RU58841 ihangana na dihydrotestosterone kugira ngo ikomeze urugero rwa DHT mu rugero rusanzwe, bityo ikagenzura uruziga rw'imikurire y'umusatsi. Itera imbaraga guhindura imisatsi mishya mu mikurire y'umusatsi ya anagen binyuze mu kwinjira mu cyiciro cya anagen. Guha imisatsi yangiritse umwanya wo gusubira mu cyiciro gisanzwe cyo gukura bifasha uturemangingo gukira. Yongera kandi amaraso ajya mu mikurire yangiritse kandi ikayifasha kongera kwiyubaka. Ku rundi ruhande, RU58841 (RU-58841) ikora ifatanye na androgen receptors mu mikurire y'umusatsi. Bityo androgens ntizigira amahirwe yo gufata no gutangira uruhererekane rw'imikurire ya androgenetic no gutangira inzira yitwa miniaturization. Byagaragaye ko ihagarika ubu butumwa bwo gutakaza umusatsi kugira ngo imikurire isanzwe y'umusatsi ikomeze.
Ikiranga
(1) Ishobora gukumira gutakaza umusatsi: RU58841 ni umuti wihariye ubuza imisemburo, ushobora gukumira uruvange rwa androgen n'uturemangingo tw'umusatsi wo mu mutwe, bityo bikagabanya ibyago byo gutakaza umusatsi.
(2) Kwinjizwa neza: RU58841 ifite uburemere buto bwa molekile, imiterere yoroshye, kandi yoroshye kuyinjizwa. Ishobora kwinjira mu mubiri vuba kandi igatangira gukora mu gihe gito.
(3) Guhitamo cyane androgen: RU58841 ishobora kubuza androgen gukora neza idakoze ku zindi misemburo.
(4) Igihe kirekire cyo gukora: RU58841 ifite igice cy'ubuzima kirekire mu mubiri, ishobora kubuza buri gihe ingaruka za androgen, kandi igihe cy'imikorere gishobora kugera ku masaha 48.
(5) Ubuziranenge buhanitse: Binyuze mu gucukura ibintu mu buryo bw’umwimerere no mu gukora ibintu byiza, iterambere rya RU58841 rishobora kubona ibicuruzwa bifite ubuziranenge buhanitse.
Porogaramu
Mu bushakashatsi n'igeragezwa ry'ubuvuzi, RU58841 byagaragaye ko yongera umuvuduko wo kwiyongera kw'uturemangingo mu turemangingo twa stromal, yongera ukwiyongera kw'uturemangingo mu turemangingo tw'inyuma tw'urupapuro rw'umuzi kandi yongera uburebure bw'umusatsi n'ubucucike, bityo RU58841 ni umuti ukorerwaho ubushakashatsi mu kuvura indwara ya androgenetic alopecia. Ihame nyamukuru ry'imikorere ni ukubuza uruvange rwa DHT na AR by'udusimba tw'umusatsi, akenshi bikoreshwa mu kuvura ibibazo byo gutakaza umusatsi no gutakaza umusatsi.
