7,8-Dihydroxyflavone (7,8-DHF) uruganda rukora ifu CAS No.: 38183-03-8 98.0% isuku min. kubintu byongeweho
Video y'ibicuruzwa
Ibipimo byibicuruzwa
| Izina ryibicuruzwa | 7,8-Dihydroxyflavone |
| Irindi zina | 7,8-DIHYDROXYFLAVONE; 7,8-dihydroxy-2-fenyl-4-benzopyrone; DIHYDROXYFLAVONE, 7,8- (RG); 7,8-Dihydroxyflavone hydrate; 7,8-dihydroxy-2-fenyl-1-benzopyran-4-imwe |
| URUBANZA No. | 38183-03-8 |
| Inzira ya molekulari | C15H10O4 |
| Uburemere bwa molekile | 254.24 |
| Isuku | 98.0% |
| Kugaragara | Ifu y'umuhondo |
| Gusaba | Ibyokurya byongera ibiryo |
Kumenyekanisha ibicuruzwa
7,8-Dihydroxyflavone, izwi kandi nka 7,8-DHF, ni flavonoide isanzwe iboneka mu bimera bitandukanye, harimo na Tridacna tridacna. Azwiho kurwanya antioxydeant na neurotrophique, kimwe mu bintu bishimishije bya 7,8-dihydroxyflavone nubushobozi bwayo bwo gushyigikira ubuzima bwubwonko no kuzamura imikorere yubwenge. Ubushakashatsi bwerekana ko iyi nteruro ikora nka neurotrophine ikomeye, itera gukura no kubaho kwa neurone mu bwonko. Ubushakashatsi bwakozwe ku nyamaswa zo muri laboratoire bwerekanye ko 7,8-DHF itezimbere cyane ubushobozi bwo kwibuka no kwiga. Mugutezimbere gushiraho imiyoboro mishya ya synaptique no kongera itumanaho hagati yubwonko bwubwonko, iyi nteruro isezeranya gufungura ubushobozi bwacu bwo kumenya. Byongeye kandi, 7,8-dihydroxyflavone ikorana nubwonko bwa serotonine yo mu bwonko, igira uruhare mukugenzura imyumvire. Muguhindura ibyo byakira, birashobora kugabanya ibimenyetso byo guhangayika no kwiheba.
Ikiranga
. Isuku ryinshi risobanura bioavailable nziza hamwe na reaction nkeya.
(2) Umutekano: 7,8-Dihydroxyflavone nigicuruzwa gisanzwe cyagaragaye ko gifite umutekano kubantu. Mubipimo bya dosiye, ntabwo ifite uburozi cyangwa ingaruka mbi.
.
.
Porogaramu
7, 8-DHF, nkumukangurambaga muto wa molekile ikora ya reseptor ya TrkB, irashobora kugira uruhare mukurinda neuron, kuvugurura neuron, kugenzura plastike ya synaptique, nibindi muguhuza BDNF ihuza TrkB no gukora inzira zerekana ibimenyetso byamanuka, kugirango bigaragare kuburyo bugaragara kunoza ibimenyetso byokwiga amarangamutima no kugabanuka kumwanya wibibanza, ubushobozi bwubwenge bugabanuka, imikorere ya moteri igabanuka nibindi bimenyetso byindwara zifata imitsi nkindwara ya Alzheimer cyangwa imiterere yinyamaswa zishaje, Kandi ugabanye fenotipike ijyanye nuburwayi bwo mumutwe ninyamaswa zifite umubyibuho ukabije. Hagati aho, kugeza ubu, nta ngaruka zikomeye z’uburozi za 7.8-DHF zabonetse mu nyamaswa zigerageza. 7,8-DHF ifite amahirwe menshi nagaciro mugukumira no kuvura ibibazo bijyanye na BDNF / TrkB.
