Uruganda rwa Mitoquinone Bromide No. CAS: 336184-91-9 Ubuziranenge bwa 25% ku gipimo cy'ibikoreshwa mu nyongeramusaruro
Ibipimo by'ibicuruzwa
| Izina ry'igicuruzwa | Mitoquinone Bromide |
| Irindi zina | mitoquinone bromide Mito-Q MitoQ mitoquinone cation ya mitoquinone (10-(4,5-Dimethoxy-2-methyl-3,6-dioxocyclohexa-1,4-dien-1-yl)decyl)trifenilphosphonium bromide DMRUQISFFVFDWGE-UHFFFAOYSA-M 10-(6'-ubiquinol)decyltrifenilfosfonium J-690299 [10-(4,5-Dimethoxy-2-methyl-3,6-dioxo-1,4-cyclohexadien-1-yl)decyl]triphenyl-phosphonium Bromide |
| Nimero ya CAS | 336184-91-9 |
| Ifishi y'ingirabuzimafatizo | C37H44O4BrP |
| Uburemere bwa molekile | 663.6 |
| Ubwiza | 25% |
| Isura | Ifu y'umuhondo cyangwa umuhondo woroshye |
| Gupakira | 1kg/umufuka, 25kg/umufuka |
| Porogaramu | Ibikoresho by'inyongera ku mirire |
Intangiriro y'ibicuruzwa
Mitoquinone bromide ni kimwe mu bigize Coenzyme Q10 byagaragaye ko bifite imbaraga zo kurwanya indwara. Mitoquinone, izwi kandi nka MitoQ, ni ubwoko bwihariye bwa Coenzyme Q10 (CoQ10) bwibasira cyane cyane mitochondria, ingufu z'uturemangingo. Bitandukanye na antioxydants zisanzwe zishobora kugorwa no kwinjira mu ruhu rw'imitochondria, Mitoquinone yakozwe kugira ngo igere kuri iyi organelle y'ingenzi aho igira ingaruka zikomeye zo kurwanya indwara. Bromide ni iyoni ifite ingufu nke ifite formula ya chemical Br⁻. Ni igice cy'ingenzi mu buryo butandukanye bwo kurwanya indwara, cyane cyane mu buryo bwa SN2 aho ishobora gukora nk'ikintu kiyitera imbaraga cyangwa ionizing radical. Mitoquinone bromide ijya muri mitochondria binyuze mu guhuza covalent na triphenylphosphine cation ya lipophilic. Bitewe n'ubushobozi bunini bwa mitochondrial membrane, cation yiyongera inshuro zigera ku 1.000 muri mitochondria kurusha antioxydants zitari zigamije nka Coenzyme Q cyangwa ibindi bimera byayo, bigatuma antioxydants zishobora gukumira lipid peroxidation no kurinda mitochondria kwangirika kwa oxidative. Mu gukumira ukwangirika kwa oxidative kwa mitochondrial mu buryo bwihariye, birinda urupfu rw'uturemangingo. Mitoquinone bromide ishobora kuba umuhuza w'ingirakamaro mu gukoresha ogisijeni ya mitochondrial.
Ikiranga
(1) Ubuziranenge bwinshi: Mitoquinone bromide ishobora kubona ibicuruzwa bifite ubuziranenge bwinshi binyuze mu gutunganya ikorwa ryayo. Ubuziranenge bwinshi busobanura ko binyabuzima biboneka neza kandi ingaruka mbi zikaba nke.
(2) Umutekano: Umutekano mwinshi, ingaruka mbi nke.
(3) Gutuza: Mitoquinone bromide ifite ubutuza bwiza kandi ishobora gukomeza imikorere yayo n'ingaruka zayo mu bidukikije bitandukanye no mu buryo butandukanye bwo kubika.
Porogaramu
Mu rwego rwo gusaza, kugabanuka k'imikorere ya mitochondrial no kwiyongera k'ibyangiritse bya ogisijeni ni ibintu by'ingenzi mu gusaza. Ingaruka za mitoquinones zigamije kurwanya ogisijeni zituma ziba abakandida bakomeye bo gufata ingamba zigamije guteza imbere gusaza neza no kuramba. Byongeye kandi, imiterere yayo yo kurinda ubwonko ishobora gutinza kugabanuka k'ubwonko bifitanye isano n'izabukuru, bigatuma dushobora kugumana imbaraga zo gutekereza mu gihe cyo gusaza. Mitoquinone kandi yakuruye ibitekerezo kubera ubushobozi bwayo bwo kurwanya ogisijeni mu rwego rwo kwita ku ruhu. Uruhu ruhora ruhura n'ibintu bibangamira ibidukikije kandi rushobora kwangirika cyane. Hamwe no gukoresha imbaraga za quinones za mitochondrial, uruhu rukiri ruto kandi rukayangana rushobora kugerwaho.
