Amino Tadalafil ikora ifu CAS No.: 385769-84-6 98% isuku min. kubintu byongeweho
Video y'ibicuruzwa
Ibipimo byibicuruzwa
| Izina ryibicuruzwa | Amino Tadalafil |
| Irindi zina | . (6R, 12aR) -2-Amino-6- 3,4-b] indole-1,4-dione; AminoTadalafil (6R, 12Ar) -2-Amino-6- (1,3-Benzodioxol-5-Yl) -2,3,6,7,12,12A -Hexahydropyrazino [1 ', 2': 1,6] Pyrido [3,4-B] Indole-1,4-Dione; (6R, 12aR) -2-Amino-6- (benzo [d] [1,3 dioxol-5-yl) -2,3,6,7,12,12a-hexahydropyrazino [1 ', 2': 1,6] pyrido [3,4-b] indol-1,4-dione; (6R , 12aR) -2-amino-6- (benzo [d] [1,3] dioxol-5-yl) -2,3,12,12a-tetrahydropyrazino [1 ', 2': 1,6] pyrido [3 , 4-b] indole-1,4 (6H, 7H) -dione |
| URUBANZA No. | 385769-84-6 |
| Inzira ya molekulari | C21H18N4O4 |
| Uburemere bwa molekile | 390.39 |
| Isuku | 98.0% |
| Kugaragara | Ifu yera-yera |
| Gusaba | Ibyokurya byongera ibiryo |
Kumenyekanisha ibicuruzwa
Amino Tadalafil nikintu gishya ugereranije, gikomoka kuri tadalafil, kigenda gikundwa cyane mubijyanye no kudakora neza (ED). Ihuza aside amine na tadalafil, inhibitor ya FDA yemewe na PDE5 ikoreshwa cyane mukuvura ED. Ikora mukwongera amaraso mumibonano mpuzabitsina, bigatuma abagabo bagera no gukomeza igitsina. Ku rundi ruhande, aside amine igira uruhare runini mu mikorere itandukanye y'umubiri, harimo no gukora poroteyine, ari zo zubaka ingirangingo n'ingingo. Ihuriro ryibi bintu byombi ryateguwe kugirango Tadalafil ikore neza mukuvura ED. Kandi amino Tadalafil ni verisiyo yatezimbere ifite ubushobozi budasanzwe, izamura imikorere nuburyo bwinshi bwabayibanjirije. Imiterere yimiti ikomeza kumera nka Tadalafil, ariko binyuze mugutangiza amatsinda ya amino, ibona imico idasanzwe ituma igaragara mumiti yimiti. Kimwe na tadalafil, Amino Tadalafil ikora ibuza fosifodiyesterase 5 (PDE5), enzyme ishinzwe kumena cyclic guanosine monophosphate (cGMP) mumubiri. cGMP nikintu gisanzwe gitera kuruhura imiyoboro yamaraso, bityo bikongera umuvuduko wamaraso. Muguhagarika PDE5, amino Tadalafil ituma kwirundanya kwa cGMP, bityo bikongerera vasodilasiyo no kunoza amaraso. Byongeye kandi, abashakashatsi bakoze ubushakashatsi ku bushobozi bwayo bwo gufasha kuvura hyperplasia nziza ya prostate (BPH) mu guteza imbere amaraso muri prostate.
Ikiranga
(1) Isuku ryinshi: Amino Tadalafil irashobora kubona ibicuruzwa byera cyane binyuze mu gutunganya umusaruro. Isuku ryinshi risobanura bioavailable nziza hamwe na reaction nkeya.
(2) Umutekano: Umutekano mwinshi, reaction nkeya.
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Porogaramu
Amino Tadalafil ni inhibitor ya PDE5 ifite ingaruka za farumasi nka tadalafil. Muguhuza aside amine na tadalafil, amino Tadalafil yatekerezaga ko ifite akamaro mukuvura imikorere mibi yumugabo kuruta tadalafil yonyine. Acide Amino irashobora gufasha kongera umuvuduko wamaraso no gushyigikira imikorere rusange yimiti. Byongeye kandi, irashobora kunoza ibimenyetso byimikorere idahwitse (ED) ihagarika ibikorwa bya enzyme ya PDE5 kugirango itume amaraso atembera mumyanya myibarukiro yumugabo. Ugereranije na tadalafil, amino Tadalafil ihinduranya buhoro buhoro mumubiri kandi irashobora gutanga ingaruka zirambye. Ibi biha amino Tadalafil imbaraga zikomeye mukuvura ED.
